Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling.
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Insulin: a wonder drug in the critically ill?Is insulin an endogenous cardioprotector?The impact of glucose-insulin-potassium infusion in acute myocardial infarction on infarct size and left ventricular ejection fraction [ISRCTN56720616]Histone Deacetylases Exert Class-Specific Roles in Conditioning the Brain and Heart Against Acute Ischemic InjuryCutting through the complexities of mTOR for the treatment of strokeAspirin before reperfusion blunts the infarct size limiting effect of atorvastatinThe TSC complex is required for the benefits of dietary protein restriction on stress resistance in vivoInsulin-stimulated cytosol alkalinization facilitates optimal activation of glucose transport in cardiomyocytesThe effect of perioperative insulin treatment on cardiodepression in mild adiposity in mice.Acute hyperglycemia abolishes ischemic preconditioning by inhibiting Akt phosphorylation: normalizing blood glucose before ischemia restores ischemic preconditioning.Timing of adenosine 2A receptor stimulation relative to reperfusion has differential effects on infarct size and cardiac function as assessed in mice by MRIActivation of glycogen synthase in myocardium induced by intermittent hypoxia is much lower in fasted than in fed rats.High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells.Pivotal role of mTORC2 and involvement of ribosomal protein S6 in cardioprotective signalingMitochondrial integrity: preservation through Akt/Pim-1 kinase signaling in the cardiomyocytePI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injuryHyperglycemia-induced oxidative stress and heart disease-cardioprotective effects of rooibos flavonoids and phenylpyruvic acid-2-O-β-D-glucoside.Single dose GLP-1-Tf ameliorates myocardial ischemia/reperfusion injury.Cardioprotection by a nonerythropoietic, tissue-protective peptide mimicking the 3D structure of erythropoietinRapamycin-Induced apoptosis in HGF-stimulated lens epithelial cells by AKT/mTOR, ERK and JAK2/STAT3 pathwaysHuman catestatin peptides differentially regulate infarct size in the ischemic-reperfused rat heartPharmacologic prophylaxis for atrial fibrillation following cardiac surgery: a systematic review.Oleanolic acid: a novel cardioprotective agent that blunts hyperglycemia-induced contractile dysfunction.Role of Endothelial Cells in Myocardial Ischemia-Reperfusion Injury.Reperfusion therapy with low-dose insulin or insulin-like growth factor 2; myocardial function and infarct size in a porcine model of ischaemia and reperfusion.Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling.Ginsenoside Rd attenuates myocardial ischemia/reperfusion injury via Akt/GSK-3β signaling and inhibition of the mitochondria-dependent apoptotic pathwayLeptin, the obesity-associated hormone, exhibits direct cardioprotective effectsPhosphoinositide 3-kinase gamma/delta inhibition limits infarct size after myocardial ischemia/reperfusion injury.Mechanisms underlying acute protection from cardiac ischemia-reperfusion injuryA novel cardioprotective p38-MAPK/mTOR pathway.Diabetes and cardiovascular disease: the road to cardioprotection.Insulin Protects Cardiac Myocytes from Doxorubicin Toxicity by Sp1-Mediated Transactivation of SurvivinAKT/GSK3 signaling pathway and schizophreniaHypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling.Toll-interacting protein contributes to mortality following myocardial infarction through promoting inflammation and apoptosisHyperinsulinemic Normoglycemia Does Not Meaningfully Improve Myocardial Performance during Cardiac Surgery: A Randomized Trial.Insulin treatment before resuscitation following hemorrhagic shock improves cardiac contractility and protects the myocardium in the isolated rat heart.How does blood glucose control with insulin save lives in intensive care?Activating Akt and the brain's resources to drive cellular survival and prevent inflammatory injury
P2860
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P2860
Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Myocardial protection by insul ...... inase cell-survival signaling.
@en
Myocardial protection by insul ...... inase cell-survival signaling.
@nl
type
label
Myocardial protection by insul ...... inase cell-survival signaling.
@en
Myocardial protection by insul ...... inase cell-survival signaling.
@nl
prefLabel
Myocardial protection by insul ...... inase cell-survival signaling.
@en
Myocardial protection by insul ...... inase cell-survival signaling.
@nl
P2093
P356
P1433
P1476
Myocardial protection by insul ...... inase cell-survival signaling.
@en
P2093
P304
P356
10.1161/HH2401.101385
P577
2001-12-01T00:00:00Z