Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling. - Wikidata - wikimedia - TriplyDB

Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling.

Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling.

http://www.wikidata.org/entity/Q35840605

about

Autophagy and cardiovascular aging: lesson learned from rapamycin.Why men age faster but reproduce longer than women: mTOR and evolutionary perspectives Autophagy in health and disease. 2. Regulation of lipid metabolism and storage by autophagy: pathophysiological implications.Early endosomal antigen 1 (EEA1) is an obligate scaffold for angiotensin II-induced, PKC-alpha-dependent Akt activation in endosomes Differential effects of atorvastatin on autophagy in ischemic and nonischemic myocardium in Ossabaw swine with metabolic syndrome.Hormesis does not make sense except in the light of TOR-driven aging.Perspectives of Targeting mTORC1-S6K1 in Cardiovascular Aging Molecular damage in cancer: an argument for mTOR-driven aging mTOR complex 2 signaling and functions Transition from obesity to metabolic syndrome is associated with altered myocardial autophagy and apoptosis.CD36 protein influences myocardial Ca2+ homeostasis and phospholipid metabolism: conduction anomalies in CD36-deficient mice during fasting.Myocardial AKT: the omnipresent nexus.Aging is not programmed: genetic pseudo-program is a shadow of developmental growth.Rapamycin treatment of healthy pigs subjected to acute myocardial ischemia-reperfusion injury attenuates cardiac functions and increases myocardial necrosis.Resveratrol regulates autophagy signaling in chronically ischemic myocardium.Obesity-metabolic derangement exacerbates cardiomyocyte loss distal to moderate coronary artery stenosis in pigs without affecting global cardiac function.Autophagy in vascular disease.Hypercholesterolemia downregulates autophagy in the rat heart.Unmasking the janus faces of autophagy in obesity-associated insulin resistance and cardiac dysfunction.Autophagy, myocardial protection, and the metabolic syndrome.Strategies for the discovery of anti-aging compounds.AICAR treatment for 14 days normalizes obesity-induced dysregulation of TORC1 signaling and translational capacity in fasted skeletal muscle.Boosting autophagy in the diabetic heart: a translational perspective.Insights for Oxidative Stress and mTOR Signaling in Myocardial Ischemia/Reperfusion Injury under Diabetes.Methyl-beta-cyclodextrin suppresses hyaluronan synthesis by down-regulation of hyaluronan synthase 2 through inhibition of Akt.Cholesterol-Lowering Gene Therapy Counteracts the Development of Non-ischemic Cardiomyopathy in Mice.Tetrandrine, an Activator of Autophagy, Induces Autophagic Cell Death via PKC-α Inhibition and mTOR-Dependent Mechanisms.Rheb is a critical regulator of autophagy during myocardial ischemia: pathophysiological implications in obesity and metabolic syndrome.

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P2860

Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling.

http://www.wikidata.org/entity/Q35840605

description

2009 nî lūn-bûn

@nan

2009年の論文

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2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

2009年论文

@zh

2009年论文

@zh-cn

name

Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling.

@ast

Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling.

@en

type

label

Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling.

@ast

Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling.

@en

prefLabel

Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling.

@ast

Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling.

@en

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Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling.

@en

P2093

Cesario Bianchi

http://www.w3.org/2001/XMLSchema#string

Frank W Sellke

http://www.w3.org/2001/XMLSchema#string

Hilary P Glazer

http://www.w3.org/2001/XMLSchema#string

Richard T Clements

http://www.w3.org/2001/XMLSchema#string

Robert M Osipov

http://www.w3.org/2001/XMLSchema#string

P2860

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

Cardiac regulation by phosphoinositide 3-kinases and PTEN

REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species

Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

Phosphoinositide 3-kinase accelerates necrotic cell death during hypoxia

The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C

Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

Modulation of the protein kinase activity of mTOR.

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1738-1746

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scholarly article

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10.4161/CC.8.11.8619

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11

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8

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19395857

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hypercholesterolemia

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3308015

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