Influence of chemical stability on the activity of the antimetastasis ruthenium compound NAMI-A.
about
Redox activation of metal-based prodrugs as a strategy for drug deliveryRuthenium anticancer compounds: myths and realities of the emerging metal-based drugs.Kinetic and mechanistic studies on reactions of diruthenium(II,III) with biologically relevant reducing agents.Ru binding to RNA following treatment with the antimetastatic prodrug NAMI-A in Saccharomyces cerevisiae and in vitroArene-Ru(II)-chloroquine complexes interact with DNA, induce apoptosis on human lymphoid cell lines and display low toxicity to normal mammalian cells.Unusual DNA binding modes for metal anticancer complexes.New clues for platinum antitumor chemistry: kinetically controlled metal binding to DNA.Fighting Cancer with Transition Metal Complexes: From Naked DNA to Protein and Chromatin Targeting Strategies.Anticancer activity of metal complexes: involvement of redox processes.Current State of Metal-Based Drugs for the Efficient Therapy of Lung Cancers and Lung Metastases.Anticancer Activity Studies of Ruthenium(II) Complex Toward Human Osteosarcoma HOS Cells.Discovery of a dual-targeting organometallic ruthenium complex with high activity inducing early stage apoptosis of cancer cells.Effects of the ruthenium-based drug NAMI-A on the roles played by TGF-β1 in the metastatic process.RNA-seq analysis of the whole transcriptome of MDA-MB-231 mammary carcinoma cells exposed to the antimetastatic drug NAMI-A.Dual-targeting organometallic ruthenium(II) anticancer complexes bearing EGFR-inhibiting 4-anilinoquinazoline ligands.Influence of the binding of reduced NAMI-A to human serum albumin on the pharmacokinetics and biological activity.NAMI-A is highly cytotoxic toward leukaemia cell lines: evidence of inhibition of KCa 3.1 channels.Analysis of the cytotoxic effects of ruthenium-ketoconazole and ruthenium-clotrimazole complexes on cancer cells.Influence of ascorbic acid on the activity of the investigational anticancer drug KP1019.Functionalization of carboxylated multiwall nanotubes with imidazole derivatives and their toxicity investigations.Arene ruthenium complexes as anticancer agents.Synthesis, antineoplastic and cytotoxic activities of some mononuclear Ru(II) complexes.Characterization of a ruthenium(III)/NAMI-A adduct with bovine serum albumin that exhibits a high anti-metastatic activity.DNA-metallodrugs interactions signaled by electrochemical biosensors: an overview.Antinociceptive and antitumor activity of novel synthetic mononuclear Ruthenium (II) compounds.Tumor apoptosis induced by ruthenium(II)-ketoconazole is enhanced in nonsusceptible carcinoma by monoclonal antibody to EGF receptor.Protein metalation by metal-based drugs: X-ray crystallography and mass spectrometry studies.Possible Molecular Targets of Novel Ruthenium Complexes in Antiplatelet Therapy.The contrasting chemical reactivity of potent isoelectronic iminopyridine and azopyridine osmium(ii) arene anticancer complexesRu(II)/bisphosphine/diimine/amino acid complexes: diastereoisomerism, cytotoxicity, and inhibition of tumor cell adhesion to collagen type IKinetics and mechanistic investigation into the possible activation of imidazolium trans-[tetrachloridodimethylsulfoxideimidazoleruthenate(iii)], NAMI-A, by 2-mercaptoethane sulfonate
P2860
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P2860
Influence of chemical stability on the activity of the antimetastasis ruthenium compound NAMI-A.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Influence of chemical stabilit ...... sis ruthenium compound NAMI-A.
@en
Influence of chemical stabilit ...... sis ruthenium compound NAMI-A.
@nl
type
label
Influence of chemical stabilit ...... sis ruthenium compound NAMI-A.
@en
Influence of chemical stabilit ...... sis ruthenium compound NAMI-A.
@nl
prefLabel
Influence of chemical stabilit ...... sis ruthenium compound NAMI-A.
@en
Influence of chemical stabilit ...... sis ruthenium compound NAMI-A.
@nl
P2093
P1476
Influence of chemical stabilit ...... asis ruthenium compound NAMI-A
@en
P2093
G Mestroni
M Cocchietto
P304
P356
10.1016/S0959-8049(01)00389-6
P577
2002-02-01T00:00:00Z