about
DNA as a possible target for antitumor ruthenium(III) complexesNew water-soluble ruthenium(II) terpyridine complexes for anticancer activity: synthesis, characterization, activation kinetics, and interaction with guanine derivatives.The unprecedented bridging coordination mode of 1,1-cyclobutane dicarboxylate (mu-cbdc-O,O') stabilized by intramolecular hydrogen bonds in ruthenium(II) complexes.Synthesis and chemical-pharmacological characterization of the antimetastatic NAMI-A-type Ru(III) complexes (Hdmtp)[trans-RuCl4(dmso-S)(dmtp)], (Na)[trans-RuCl4(dmso-S)(dmtp)], and [mer-RuCl3(H2O)(dmso-S)(dmtp)] (dmtp = 5,7-dimethyl[1,2,4]triazolo[1Replacement of chlorides with dicarboxylate ligands in anticancer active Ru(II)-DMSO compounds: a new strategy that might lead to improved activity.1-(2-Picolyl)-substituted 1,2,3-triazole as novel chelating ligand for the preparation of ruthenium complexes with potential anticancer activity.Ruthenium antimetastatic agents.A categorization of metal anticancer compounds based on their mode of action.Water-soluble Ru(II)- and Ru(III)-halide-PTA complexes (PTA=1,3,5-triaza-7-phosphaadamantane): Chemical and biological properties.Phototoxic Activity and DNA Interactions of Water-Soluble Porphyrins and Their Rhenium(I) Conjugates.NAMI-A is highly cytotoxic toward leukaemia cell lines: evidence of inhibition of KCa 3.1 channels.New uses for old drugs: attempts to convert quinolone antibacterials into potential anticancer agents containing ruthenium.Factors that influence the antiproliferative activity of half sandwich Ru(II)-[9]aneS3 coordination compounds: activation kinetics and interaction with guanine derivatives.New half sandwich Ru(II) coordination compounds for anticancer activity.New half sandwich-type Ru(II) coordination compounds characterized by the fac-Ru(dmso-S)3 fragment: influence of the face-capping group on the chemical behavior and in vitro anticancer activity.Ruthenium-porphyrin conjugates with cytotoxic and phototoxic antitumor activity.Half-sandwich Ru II[9]aneS3 complexes structurally similar to antitumor-active organometallic piano-stool compounds: preparation, structural characterization and in vitro cytotoxic activity.Free exchange across cells, and echistatin-sensitive membrane target for the metastasis inhibitor NAMI-A (imidazolium trans-imidazole dimethyl sulfoxide tetrachlororuthenate) on KB tumor cells.Distinct effects of dinuclear ruthenium(III) complexes on cell proliferation and on cell cycle regulation in human and murine tumor cell lines.Synthetic strategies towards ruthenium-porphyrin conjugates for anticancer activity.Photophysics of pyridylporphyrin Ru(II) adducts: heavy-atom effects and intramolecular decay pathways.Influence of chemical stability on the activity of the antimetastasis ruthenium compound NAMI-A.A functionalized noncovalent macrocyclic multiporphyrin assembly from a dizinc(II) bis-porphyrin receptor and a free-base dipyridylporphyrin.Solution, solid state and biological characterization of ruthenium(III)-DMSO complexes with purine base derivatives.Novel water-soluble (99m)Tc(I)/Re(I)-porphyrin conjugates as potential multimodal agents for molecular imaging.Wavelength-dependent electron and energy transfer pathways in a side-to-face ruthenium porphyrin/perylene bisimide assembly.Structural and photophysical characterization of multichromophoric pyridylporphyrin-rhenium(i) conjugates.Pyridylporphyrin metallacycles with a slipped cofacial geometry: spectroscopic, X-ray, and photophysical characterization.Influence of the anionic ligands on the anticancer activity of Ru(II)-dmso complexes: Kinetics of aquation and in vitro cytotoxicity of new dicarboxylate compounds in comparison with their chloride precursors.Self-assembled metallacycles with pyrazine edges: a new example in which the unexpected molecular triangle prevails over the expected molecular square.New cationic and neutral Ru(II)- and Os(II)-dmso carbonyl compounds.Anti-leukaemic action of RuCl2 (DMSO)4 isomers and prevention of brain involvement on P388 leukaemia and on P388/DDP subline.Towards matched pairs of porphyrin-Re(I) /(99m) Tc(I) conjugates that combine photodynamic activity with fluorescence and radio imaging.Effects of NAMI-A and some related ruthenium complexes on cell viability after short exposure of tumor cells.Antineoplastic effect of mer-trichlorobisdimethylsulphoxideaminorutheniumIII against murine tumors: comparison with cisplatin and with ImH[RuIm2Cl4].Reaction of cis-RuII(DMSO)4Cl2 with DNA and with some of its bases in aqueous solutionThirty Years of the Drug Candidate NAMI-A and the Myths in the Field of Ruthenium Anticancer Compounds: A Personal PerspectivePhase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapySynthesis and Reactivity of Ru-, Os-, Rh-, and Ir-Halide−Sulfoxide Complexes†Water-Soluble Ruthenium(II) Carbonyls with 1,3,5-Triaza-7-phosphoadamantane
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
ricercatore
@it
հետազոտող
@hy
name
Enzo Alessio
@ast
Enzo Alessio
@en
Enzo Alessio
@es
Enzo Alessio
@nl
Enzo Alessio
@sl
type
label
Enzo Alessio
@ast
Enzo Alessio
@en
Enzo Alessio
@es
Enzo Alessio
@nl
Enzo Alessio
@sl
prefLabel
Enzo Alessio
@ast
Enzo Alessio
@en
Enzo Alessio
@es
Enzo Alessio
@nl
Enzo Alessio
@sl
P1006
P214
P244
P1006
P106
P1153
7006612139
P21
P214
P244
P31
P496
0000-0002-4908-9400
P569
1958-01-01T00:00:00Z
P735
P7859
lccn-n89107442