A clonal culture system demonstrates that IL-4 induces a subpopulation of noncytolytic T cells with low CD8, perforin, and granzyme expression.
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Interferon-gamma and interleukin-4 reciprocally regulate CD8 expression in CD8+ T cellsThe multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cellsUse of praziquantel as an adjuvant enhances protection and Tc-17 responses to killed H5N1 virus vaccine in micePraziquantel facilitates IFN-γ-producing CD8+ T cells (Tc1) and IL-17-producing CD8+ T cells (Tc17) responses to DNA vaccination in miceProspects for an influenza vaccine that induces cross-protective cytotoxic T lymphocytes.The duplicitous effects of interleukin 4 on tumour immunity: how can the same cytokine improve or impair control of tumour growth?Alternative activation of tumor-associated macrophages by IL-4: priming for protumoral functions.Single-cell perforin and granzyme expression reveals the anatomical localization of effector CD8+ T cells in influenza virus-infected mice.Profiling the CD8low phenotype, an alternative career choice for CD8 T cells during primary differentiation.Detuning CD8 T cells: down-regulation of CD8 expression, tetramer binding, and response during CTL activationTargeting IL4/IL4R for the treatment of epithelial cancer metastasis.Systemic reduction of interleukin-4 or interleukin-10 fails to reduce the frequency or severity of experimental cytomegalovirus retinitis in mice with retrovirus-induced immunosuppression.Pancreatic lipase-related protein 2 (PLRP2) induction by IL-4 in cytotoxic T lymphocytes (CTLs) and reevaluation of the negative effects of its gene ablation on cytotoxicity.Epigenetic plasticity of Cd8a locus during CD8(+) T-cell development and effector differentiation and reprogramming.Quantitative assessment of the functional plasticity of memory CD8(+) T cells.Blockade of programmed death-1/programmed death ligand pathway enhances the antitumor immunity of human invariant natural killer T cells.Malaria - how this parasitic infection aids and abets EBV-associated Burkitt lymphomagenesis.Interleukin-4-induced loss of CD8 expression and cytolytic function in effector CD8 T cells persists long term in vivo.Severe feline sporotrichosis associated with an increased population of CD8low cells and a decrease in CD4⁺ cells.IL-4: an important cytokine in determining the fate of T cells.Hydrolysis of tumor cell lipids after CTL-mediated death.Interleukin-4 impairs granzyme-mediated cytotoxicity of Simian virus 40 large tumor antigen-specific CTL in BALB/c mice.The phenotype of type 1 and type 2 CD8+ T cells activated in vitro is affected by culture conditions and correlates with effector activity.Role of Chinese herbal medicinal ingredients in secretion of cytokines by PCV2-induced endothelial cells.IL-2 and antigen dose differentially regulate perforin- and FasL-mediated cytolytic activity in antigen specific CD4+ T cells.The genes for perforin, granzymes A-C and IFN-gamma are differentially expressed in single CD8(+) T cells during primary activation.Protection, systemic IFNgamma, and antibody responses induced by an ISCOM-based vaccine against a recent equine influenza virus in its natural host.Interleukin-4 suppresses the cytotoxic potential of in vitro generated, adaptive regulatory CD4 T cells by down-regulation of granzyme B.CD8(low)CD28(-) T Cells: A Human CD8 T-Suppressor Subpopulation With Alloantigen Specificity Induced by Soluble HLA-A2 Dimer In Vitro.Autoreactive human peripheral blood CD8+ T cells with a regulatory phenotype and function.
P2860
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P2860
A clonal culture system demonstrates that IL-4 induces a subpopulation of noncytolytic T cells with low CD8, perforin, and granzyme expression.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
A clonal culture system demons ...... orin, and granzyme expression.
@en
A clonal culture system demons ...... orin, and granzyme expression.
@nl
type
label
A clonal culture system demons ...... orin, and granzyme expression.
@en
A clonal culture system demons ...... orin, and granzyme expression.
@nl
prefLabel
A clonal culture system demons ...... orin, and granzyme expression.
@en
A clonal culture system demons ...... orin, and granzyme expression.
@nl
P2093
P1476
A clonal culture system demons ...... orin, and granzyme expression.
@en
P2093
Kathy Buttigieg
Penny Groves
Tom Kawula
P304
P356
10.4049/JIMMUNOL.168.4.1672
P407
P577
2002-02-01T00:00:00Z