Participation of protease-activated receptor-1 in thrombin-induced microglial activation.
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The emergence of proteinase-activated receptor-2 as a novel target for the treatment of inflammation-related CNS disordersThe Importance of Thrombin in Cerebral Injury and DiseaseIncreased prothrombin, apolipoprotein A-IV, and haptoglobin in the cerebrospinal fluid of patients with Huntington's diseaseLearning and memory deficits in mice lacking protease activated receptor-1.Thrombin-induced, TNFR-dependent miR-181c downregulation promotes MLL1 and NF-κB target gene expression in human microglia.Critical role for PAR1 in kallikrein 6-mediated oligodendrogliopathy.Kallikrein 6 signals through PAR1 and PAR2 to promote neuron injury and exacerbate glutamate neurotoxicity.CD40 glycoforms and TNF-receptors 1 and 2 in the formation of CD40 receptor(s) in autoimmunityLipopolysaccharide is a frequent and significant contaminant in microglia-activating factors.Galectin-9 controls CD40 signaling through a Tim-3 independent mechanism and redirects the cytokine profile of pathogenic T cells in autoimmunity.Role of oxidative stress in Parkinson's disease.Role of p38 and p44/42 mitogen-activated protein kinases in microglia.Thrombin signaling in the brain: the role of protease-activated receptors.Neuroprotective effects of activated protein C on intrauterine inflammation-induced neonatal white matter injury are associated with the downregulation of fibrinogen-like protein 2/fibroleukin prothrombinase and the inhibition of pro-inflammatory cyProtease-activated receptors in neuronal development, neurodegeneration, and neuroprotection: thrombin as signaling molecule in the brain.Transient early neurotrophin release and delayed inflammatory cytokine release by microglia in response to PAR-2 stimulation.Proteinases and signalling: pathophysiological and therapeutic implications via PARs and more.Genetic elimination of prothrombin in adult mice is not compatible with survival and results in spontaneous hemorrhagic events in both heart and brain.Minocycline reduces intracerebral hemorrhage-induced brain injury.Protease-activated receptor 1-dependent neuronal damage involves NMDA receptor function.Protease-activated receptor dependent and independent signaling by kallikreins 1 and 6 in CNS neuron and astroglial cell lines.GRK5 deficiency leads to reduced hippocampal acetylcholine level via impaired presynaptic M2/M4 autoreceptor desensitization.Blood-brain barrier pathophysiology in traumatic brain injury.Microglia and neurodegeneration: the role of systemic inflammation.The Molecular Mechanisms that Promote Edema After Intracerebral Hemorrhage.Reactive gliosis and the multicellular response to CNS damage and disease.Protease-activated receptor 4: a critical participator in inflammatory response.Activation of protease activated receptor 1 increases the excitability of the dentate granule neurons of hippocampusModulatory Role of Nurr1 Activation and Thrombin Inhibition in the Neuroprotective Effects of Dabigatran Etexilate in Rotenone-Induced Parkinson's Disease in Rats.Protease-activated receptor-1 expression in rat microglia after trimethyltin treatment.Pharmacological Tools to Study the Role of Astrocytes in Neural Network Functions.The involvement of thrombin in the pathogenesis of glioblastoma.Astrocytic control of synaptic NMDA receptors.Homeostatic effects of coagulation protease-dependent signaling and protease activated receptors.Overlooked Mechanisms in Type 1 Diabetes Etiology: How Unique Costimulatory Molecules Contribute to DiabetogenesisTargeting the thrombin receptor modulates inflammation and astrogliosis to improve recovery after spinal cord injuryInterference with protease-activated receptor 1 does not reduce damage to subventricular zone cells of immature rodent brain following exposure to blood or blood plasma.Protease-activated receptor 1 (PAR1) coupling to G(q/11) but not to G(i/o) or G(12/13) is mediated by discrete amino acids within the receptor second intracellular loop.Interference with Protease-activated Receptor 1 Alleviates Neuronal Cell Death Induced by Lipopolysaccharide-Stimulated Microglial Cells through the PI3K/Akt Pathway.Persistent protease-activated receptor 4 signaling mediates thrombin-induced microglial activation.
P2860
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P2860
Participation of protease-activated receptor-1 in thrombin-induced microglial activation.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Participation of protease-activated receptor-1 in thrombin-induced microglial activation.
@en
Participation of protease-activated receptor-1 in thrombin-induced microglial activation.
@nl
type
label
Participation of protease-activated receptor-1 in thrombin-induced microglial activation.
@en
Participation of protease-activated receptor-1 in thrombin-induced microglial activation.
@nl
prefLabel
Participation of protease-activated receptor-1 in thrombin-induced microglial activation.
@en
Participation of protease-activated receptor-1 in thrombin-induced microglial activation.
@nl
P2093
P1476
Participation of protease-activated receptor-1 in thrombin-induced microglial activation.
@en
P2093
Barry W Festoff
Bruce A Citron
Heidi E Anderson
Jamie E Zoloty
Patricia Andrade-Gordon
Syed Ameenuddin
Zhiming Suo
P304
P356
10.1046/J.0022-3042.2001.00745.X
P407
P577
2002-02-01T00:00:00Z