High levels of transduction of human dendritic cells with optimized SIV vectors.
about
New insights into an X-traordinary viral proteinHuman MX2 is an interferon-induced post-entry inhibitor of HIV-1 infectionSAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphatesInhibition of the Hantavirus Fusion Process by Predicted Domain III and Stem Peptides from Glycoprotein GcImpact of age at administration, lysosomal storage, and transgene regulatory elements on AAV2/8-mediated rat liver transductionCalpain product of WT-CRMP2 reduces the amount of surface NR2B NMDA receptor subunit.An antiproliferative genetic screening identifies a peptide aptamer that targets calcineurin and up-regulates its activity.Characterization of the alpha interferon-induced postentry block to HIV-1 infection in primary human macrophages and T cells.Mouse knockout models for HIV-1 restriction factors.Interplay between HIV entry and transportin-SR2 dependencyA cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells.Induction of pluripotent stem cells from a cynomolgus monkey using a polycistronic simian immunodeficiency virus-based vector, differentiation toward functional cardiomyocytes, and generation of stably expressing reporter lines.Identification of critical regions in human SAMHD1 required for nuclear localization and Vpx-mediated degradationVpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon.HIV-1 IN/Pol recruits LEDGF/p75 into viral particlesAdult-brain-derived neural stem cells grafting into a vein bridge increases postlesional recovery and regeneration in a peripheral nerve of adult pig.Heterologous human immunodeficiency virus type 1 lentiviral vectors packaging a simian immunodeficiency virus-derived genome display a specific postentry transduction defect in dendritic cells.Globin gene transfer as a potential treatment for the beta-thalassaemias and sickle cell disease.Isolation and characterization of human cells resistant to retrovirus infectionCell cycle features of primate embryonic stem cells.Stable reduction of CCR5 by RNAi through hematopoietic stem cell transplant in non-human primates.Stem cell factor-displaying simian immunodeficiency viral vectors together with a low conditioning regimen allow for long-term engraftment of gene-marked autologous hematopoietic stem cells in macaques.Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc.Innate immune sensing of HIV-1 by dendritic cells.Reconstitution of the myeloid and lymphoid compartments after the transplantation of autologous and genetically modified CD34+ bone marrow cells, following gamma irradiation in cynomolgus macaques.Induced pluripotent stem cells derived from rabbits exhibit some characteristics of naïve pluripotency.Characterization of simian immunodeficiency virus SIVSM/human immunodeficiency virus type 2 Vpx function in human myeloid cells.Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human componentsDevelopment and use of SIV-based Integrase defective lentiviral vector for immunization.HIV type 1 infection of plasmacytoid and myeloid dendritic cells is restricted by high levels of SAMHD1 and cannot be counteracted by Vpx.Vpx rescue of HIV-1 from the antiviral state in mature dendritic cells is independent of the intracellular deoxynucleotide concentration.Design of a novel integration-deficient lentivector technology that incorporates genetic and posttranslational elements to target human dendritic cells.HIV-2 Vpx protein interacts with interferon regulatory factor 5 (IRF5) and inhibits its function.Limelight on two HIV/SIV accessory proteins in macrophage infection: is Vpx overshadowing Vpr?Hiding in plain sight: how HIV evades innate immune responses.Actin Dynamics Regulates Dendritic Cell-Mediated Transfer of HIV-1 to T Cells.A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitisInhibition of Vpx-Mediated SAMHD1 and Vpr-Mediated Host Helicase Transcription Factor Degradation by Selective Disruption of Viral CRL4 (DCAF1) E3 Ubiquitin Ligase AssemblyPreclinical safety and efficacy of an anti-HIV-1 lentiviral vector containing a short hairpin RNA to CCR5 and the C46 fusion inhibitor.Inhibition of PrPSc formation by lentiviral gene transfer of PrP containing dominant negative mutations.
P2860
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P2860
High levels of transduction of human dendritic cells with optimized SIV vectors.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
High levels of transduction of human dendritic cells with optimized SIV vectors.
@en
High levels of transduction of human dendritic cells with optimized SIV vectors.
@nl
type
label
High levels of transduction of human dendritic cells with optimized SIV vectors.
@en
High levels of transduction of human dendritic cells with optimized SIV vectors.
@nl
prefLabel
High levels of transduction of human dendritic cells with optimized SIV vectors.
@en
High levels of transduction of human dendritic cells with optimized SIV vectors.
@nl
P2093
P356
P1433
P1476
High levels of transduction of human dendritic cells with optimized SIV vectors.
@en
P2093
Bertrand Boson
Didier Nègre
Dominique Rigal
François-Loïc Cosset
Jean-Luc Darlix
Karine Duperrier
Philippe-Emmanuel Mangeot
P304
P356
10.1006/MTHE.2002.0541
P577
2002-03-01T00:00:00Z