Lithium blocks the PKB and GSK3 dephosphorylation induced by ceramide through protein phosphatase-2A.
about
GSK-3β: A Bifunctional Role in Cell Death PathwaysLithium: the pharmacodynamic actions of the amazing ionThe role of lithium in the treatment of bipolar disorder: convergent evidence for neurotrophic effects as a unifying hypothesisA systematic review of existing data on long-term lithium therapy: neuroprotective or neurotoxic?High fluence low-power laser irradiation induces apoptosis via inactivation of Akt/GSK3β signaling pathway.Altered expression of apoptotic factors and synaptic markers in postmortem brain from bipolar disorder patients.Peripheral nervous system plasmalogens regulate Schwann cell differentiation and myelination.GSK3beta promotes apoptosis after renal ischemic injury.Novel cell death signaling pathways in neurotoxicity models of dopaminergic degeneration: relevance to oxidative stress and neuroinflammation in Parkinson's disease.Cyclin-dependent kinase 5, a node protein in diminished tauopathy: a systems biology approach.Lithium enhances survival and regrowth of spinal motoneurons after ventral root avulsion.Lithium inhibits tumorigenic potential of PDA cells through targeting hedgehog-GLI signaling pathway.Human herpesvirus 8-encoded vGPCR activates nuclear factor of activated T cells and collaborates with human immunodeficiency virus type 1 Tat.Inflammation induced by infection potentiates tau pathological features in transgenic mice.The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways.Harnessing the power of yeast to elucidate the role of sphingolipids in metabolic and signaling processes pertinent to psychiatric disorders.The transcription factor SP4 is reduced in postmortem cerebellum of bipolar disorder subjects: control by depolarization and lithium.Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions.Cyclin-Dependent kinase 5 targeting prevents β-Amyloid aggregation involving glycogen synthase kinase 3β and phosphatases.Akt as a mediator of cell death.Lithium blocks ethanol-induced modulation of protein kinases in the developing brain.Downregulation of vascular endothelial growth factor receptor-2 under oxidative stress conditions is mediated by β-transduction repeat-containing protein via glycogen synthase kinase-3β signalingReview of lithium effects on brain and blood.Lithium's gene expression profile, relevance to neuroprotection A cDNA microarray study.Bone morphogenic protein (BMP) signaling up-regulates neutral sphingomyelinase 2 to suppress chondrocyte maturation via the Akt protein signaling pathway as a negative feedback mechanismIcariin protects SH-SY5Y cells from formaldehyde-induced injury through suppression of Tau phosphorylation.Glycogen synthase kinase-3 (GSK-3) inhibition attenuates hepatocyte lipoapoptosis.Glycogen synthase kinase-3 plays a central role in mediating glucocorticoid-induced apoptosis.Mechanism of activation of PKB/Akt by the protein phosphatase inhibitor Calyculin A.A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulationAntiapoptotic activity of Akt is down-regulated by Ca2+ in myocardiac H9c2 cells. Evidence of Ca(2+)-dependent regulation of protein phosphatase 2Ac.Expression of sphingosine kinase gene in the interactions between human gastric carcinoma cell and vascular endothelial cell.PI3-kinase regulates survival of chronic lymphocytic leukemia B-cells by preventing caspase 8 activation.Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation.Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells.Neuroprotective effect of chronic lithium treatment against hypoxia in specific brain regions with upregulation of cAMP response element binding protein and brain-derived neurotrophic factor but not nerve growth factor: comparison with acute lithiumThe GSK3 kinase inhibitor lithium produces unexpected hyperphosphorylation of β-catenin, a GSK3 substrate, in human glioblastoma cells.Applications of Metals for Bone Regeneration.PTEN Overexpression Cooperates With Lithium to Reduce the Malignancy and to Increase Cell Death by Apoptosis via PI3K/Akt Suppression in Colorectal Cancer Cells.
P2860
Q21285144-B2954A1D-FC86-48B3-878B-B4F749536B5EQ22241779-471F1E8E-5888-4476-B13A-BA5ED4F1FC3AQ24651407-7E8DFEFD-30D2-4B06-84BC-CBACC8768309Q33284843-B5778B5A-B4FC-4FE7-ABAB-9D427ADCF8CDQ33648923-37F2C036-2D7C-4640-BE5C-723F0D1A029CQ33664124-3E70CEA9-3D93-4974-BF1E-AA95CAA67D77Q33685924-1CE27D58-C332-44F6-B2CB-D50CF6857C29Q33711281-1E0C764C-8503-43AF-A0DA-83E782554E74Q33925236-FBF8373E-71BE-451A-93E2-C072508E4D4DQ34113857-1D7A877E-FAA4-4DC8-A89D-398C11F11EB3Q34485199-DFEF9196-5944-4EA3-9AE0-09AFFFA129DCQ34692166-3A3A8875-DEA8-42C8-AEA2-8BEB7CB8AFDEQ34976938-82090D70-E3EA-4394-9DBA-BDA22C50F3C5Q35071072-793F30BE-8CB5-4F1E-B07B-7EC6A1BF3B4DQ35103813-13B1F7DA-C099-4F4A-8339-50F238EA775DQ35149929-6DF4CDA1-F707-4A94-A009-2F8306B82855Q35451948-4E539E64-CD41-4C4E-8A25-A5CBC63A9BEBQ35748119-0A9F4251-063F-4BDF-B5EC-985D4B328620Q35772503-1C9DFD8D-FAC2-4199-AAA6-7B3C029BF462Q36161549-B70B7DB7-1597-4D01-9296-58E9080E4973Q36518042-5D9D4FB1-DDCC-432E-BB02-4665B08AFB1AQ36684301-E1EE926D-1F07-42EE-AC66-336D2D217101Q37517959-69B2D339-F158-4BD9-99E2-8FDACB9927E1Q38318462-DAFBD4B0-FB9B-4D40-BC58-162CFE5A341AQ38382977-223FA9B9-B94D-4240-A516-8B51CB419084Q38818006-586B97AD-68FD-487D-A009-ACD837B839ECQ39621569-2FFCC94B-FC96-4F31-9420-EB19DEA85D13Q39718208-09BC0BC9-1F1A-4200-8FE3-020283C3E4E2Q39862158-CE1EEE59-B838-4F86-A72F-130B28FDC735Q39972783-24275716-6F23-4EBF-8EAA-45D25B989CC3Q40514623-BBDD3F6F-6725-47F0-95DB-2093ADEE9E94Q40711290-6C34D839-E4CB-4C1E-8EAE-924A9E891719Q42467584-A8A268B3-E0DE-4403-9181-24A7DCA66FF6Q44135113-4A03849B-1C94-433E-B479-5C23D6C20E2DQ44452025-345E2070-9A15-491C-A9A9-FF306B726883Q46652532-ECD861E0-B9CC-49B4-9A94-E1003843F86AQ47322400-F643E41A-4F28-4FE5-BB85-A1EA88F8216FQ51734259-F0CDFED5-10D2-45F0-B2B0-22777B7866ABQ53401643-7D8DA014-4C8A-478B-B982-797D017DDDEA
P2860
Lithium blocks the PKB and GSK3 dephosphorylation induced by ceramide through protein phosphatase-2A.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Lithium blocks the PKB and GSK ...... hrough protein phosphatase-2A.
@en
Lithium blocks the PKB and GSK ...... hrough protein phosphatase-2A.
@nl
type
label
Lithium blocks the PKB and GSK ...... hrough protein phosphatase-2A.
@en
Lithium blocks the PKB and GSK ...... hrough protein phosphatase-2A.
@nl
prefLabel
Lithium blocks the PKB and GSK ...... hrough protein phosphatase-2A.
@en
Lithium blocks the PKB and GSK ...... hrough protein phosphatase-2A.
@nl
P2093
P50
P1433
P1476
Lithium blocks the PKB and GSK ...... through protein phosphatase-2A
@en
P2093
Ana Cuenda
Ana María Risco
Juan C Alonso
P304
P356
10.1016/S0898-6568(01)00282-0
P577
2002-06-01T00:00:00Z