Transthyretin fibrillogenesis entails the assembly of monomers: a molecular model for in vitro assembled transthyretin amyloid-like fibrils.
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Binding of epigallocatechin-3-gallate to transthyretin modulates its amyloidogenicityTissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue cultureEpigallocatechin-3-gallate as a potential therapeutic drug for TTR-related amyloidosis: "in vivo" evidence from FAP mice modelsSystematic analysis of aggregates from 38 kinds of non disease-related proteins: identifying the intrinsic propensity of polypeptides to form amyloid fibrils.Fourier transform infrared spectroscopy provides a fingerprint for the tetramer and for the aggregates of transthyretin.Amyloid structure and assembly: insights from scanning transmission electron microscopy.Quantification of quaternary structure stability in aggregation-prone proteins under physiological conditions: the transthyretin case.Distinct annular oligomers captured along the assembly and disassembly pathways of transthyretin amyloid protofibrilsEvaluation of Nanoparticle Tracking for Characterization of Fibrillar Protein AggregatesExperimentally derived structural constraints for amyloid fibrils of wild-type transthyretinEvidence for early cytotoxic aggregates in transgenic mice for human transthyretin Leu55ProMechanisms of protein fibril formation: nucleated polymerization with competing off-pathway aggregationpH Induced Conformational Transitions in the Transforming Growth Factor β-Induced Protein (TGFβIp) Associated Corneal Dystrophy Mutants.Levels of supramolecular chirality of polyglutamine aggregates revealed by vibrational circular dichroism.Structural basis of infectious and non-infectious amyloidsDenaturation and solvent effect on the conformation and fibril formation of TGFBIp.Surface characterization of insulin protofilaments and fibril polymorphs using tip-enhanced Raman spectroscopy (TERS).Is supramolecular filament chirality the underlying cause of major morphology differences in amyloid fibrils?Considerably Unfolded Transthyretin Monomers Preceed and Exchange with Dynamically Structured Amyloid Protofibrils.Force spectroscopy reveals the presence of structurally modified dimers in transthyretin amyloid annular oligomers.Clusterin overexpression and its possible protective role in transthyretin deposition in familial amyloidotic polyneuropathy.αB-crystallin (HspB5) in familial amyloidotic polyneuropathy.Amyloidogenic properties of transthyretin-like protein (TLP) from Escherichia coli.Transthyretin binding to A-Beta peptide--impact on A-Beta fibrillogenesis and toxicity.Evaluating the effect of mutations and ligand binding on transthyretin homotetramer dynamics.A structural model of an amyloid protofilament of transthyretin.Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative.Stability and fibril formation properties of human and fish transthyretin, and of the Escherichia coli transthyretin-related protein.X-ray absorption spectroscopy reveals a substantial increase of sulfur oxidation in transthyretin (TTR) upon fibrillization.Unfolding and aggregation of transthyretin by the truncation of 50 N-terminal amino acids.Diagnostic hallmarks and pitfalls in late-onset progressive transthyretin-related amyloid-neuropathy.Structure and assembly-disassembly properties of wild-type transthyretin amyloid protofibrils observed with atomic force microscopy.Familial and Senile Amyloidosis Caused by TransthyretinCharacterization of Inter- and Intramolecular Interactions of Amyloid Fibrils by AFM-Based Single-Molecule Force Spectroscopy
P2860
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P2860
Transthyretin fibrillogenesis entails the assembly of monomers: a molecular model for in vitro assembled transthyretin amyloid-like fibrils.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Transthyretin fibrillogenesis ...... thyretin amyloid-like fibrils.
@en
Transthyretin fibrillogenesis ...... thyretin amyloid-like fibrils.
@nl
type
label
Transthyretin fibrillogenesis ...... thyretin amyloid-like fibrils.
@en
Transthyretin fibrillogenesis ...... thyretin amyloid-like fibrils.
@nl
prefLabel
Transthyretin fibrillogenesis ...... thyretin amyloid-like fibrils.
@en
Transthyretin fibrillogenesis ...... thyretin amyloid-like fibrils.
@nl
P2093
P356
P1476
Transthyretin fibrillogenesis ...... thyretin amyloid-like fibrils.
@en
P2093
P304
P356
10.1006/JMBI.2002.5441
P407
P577
2002-04-01T00:00:00Z