The ClC-3 chloride channel promotes acidification of lysosomes in CHO-K1 and Huh-7 cells.
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Anion channels, including ClC-3, are required for normal neutrophil oxidative function, phagocytosis, and transendothelial migrationThe PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteinsHerpesviruses and intermediate filaments: close encounters with the third typeA C-terminally truncated mouse Best3 splice variant targets and alters the ion balance in lysosome-endosome hybrids and the endoplasmic reticulum.Discovery of CLC transport proteins: cloning, structure, function and pathophysiologyRegulation of intracellular Cl- concentration through volume-regulated ClC-3 chloride channels in A10 vascular smooth muscle cellsMimicry of a host anion channel by a Helicobacter pylori pore-forming toxin.Random mutagenesis of Helicobacter pylori vacA to identify amino acids essential for vacuolating cytotoxic activity.Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain.The ClC-3 Cl-/H+ antiporter becomes uncoupled at low extracellular pHClC-3 chloride channel mediates the role of parathyroid hormone [1-34] on osteogenic differentiation of osteoblastsMolecular interaction and functional regulation of ClC-3 by Ca2+/calmodulin-dependent protein kinase II (CaMKII) in human malignant glioma.Electrophysiology of reactive oxygen production in signaling endosomesRole of ClC-5 in renal endocytosis is unique among ClC exchangers and does not require PY-motif-dependent ubiquitylation.Phosphatidylinositol-4-kinase type II alpha is a component of adaptor protein-3-derived vesicles.Suppression of chloride channel 3 expression facilitates sensitivity of human glioma U251 cells to cisplatin through concomitant inhibition of Akt and autophagy.Gene expression and integrated stress response in HepG2/C3A cells cultured in amino acid deficient medium.Novel CLC3 transcript variants in blood eosinophils and increased CLC3 expression in nasal lavage and blood eosinophils of asthmatics.Ca(2+)-activated chloride channels go molecular.Chloride Channel 3 Channels in the Activation and Migration of Human Blood Eosinophils in Allergic Asthma.Neuronal ClC-3 Splice Variants Differ in Subcellular Localizations, but Mediate Identical Transport Functions.Restoration of lysosomal pH in RPE cells from cultured human and ABCA4(-/-) mice: pharmacologic approaches and functional recovery.Abelson tyrosine kinase controls phagosomal acidification required for killing of Mycobacterium tuberculosis in human macrophagesCLC-0 and CFTR: chloride channels evolved from transporters.Revisiting the role of cystic fibrosis transmembrane conductance regulator and counterion permeability in the pH regulation of endocytic organelles.Physiological implications of the regulation of vacuolar H+-ATPase by chloride ions.Cell biology and physiology of CLC chloride channels and transporters.Proton electrochemical gradient: Driving and regulating neurotransmitter uptake.ClC Channels and Transporters: Structure, Physiological Functions, and Implications in Human Chloride Channelopathies.Sorting motifs of the endosomal/lysosomal CLC chloride transporters.Osteogenic role of endosomal chloride channels in MC3T3-E1 cells.Involvement of ClC-3 chloride/proton exchangers in controlling glutamatergic synaptic strength in cultured hippocampal neurons.Overexpression of CLC-3 in HEK293T cells yields novel currents that are pH dependent.Characterization of a proton-activated, outwardly rectifying anion channel.Contribution of a time-dependent and hyperpolarization-activated chloride conductance to currents of resting and hypotonically shocked rat hepatocytes.Expression of novel isoforms of the CIC-1 chloride channel in astrocytic glial cells in vitro.Identification of an N-terminal amino acid of the CLC-3 chloride channel critical in phosphorylation-dependent activation of a CaMKII-activated chloride current.A cation counterflux supports lysosomal acidification.ClC-7 is a slowly voltage-gated 2Cl(-)/1H(+)-exchanger and requires Ostm1 for transport activity.The late endosomal ClC-6 mediates proton/chloride countertransport in heterologous plasma membrane expression.
P2860
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P2860
The ClC-3 chloride channel promotes acidification of lysosomes in CHO-K1 and Huh-7 cells.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
The ClC-3 chloride channel promotes acidification of lysosomes in CHO-K1 and Huh-7 cells.
@en
The ClC-3 chloride channel promotes acidification of lysosomes in CHO-K1 and Huh-7 cells.
@nl
type
label
The ClC-3 chloride channel promotes acidification of lysosomes in CHO-K1 and Huh-7 cells.
@en
The ClC-3 chloride channel promotes acidification of lysosomes in CHO-K1 and Huh-7 cells.
@nl
prefLabel
The ClC-3 chloride channel promotes acidification of lysosomes in CHO-K1 and Huh-7 cells.
@en
The ClC-3 chloride channel promotes acidification of lysosomes in CHO-K1 and Huh-7 cells.
@nl
P2093
P1476
The ClC-3 chloride channel promotes acidification of lysosomes in CHO-K1 and Huh-7 cells.
@en
P2093
Steven A Weinman
Zhifang Zhao
P304
P356
10.1152/AJPCELL.00504.2001
P577
2002-06-01T00:00:00Z