Orientational constraints of the gp130 intracellular juxtamembrane domain for signaling.
about
Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 systemPrinciples of interleukin (IL)-6-type cytokine signalling and its regulationStructural Organization of a Full-Length gp130/LIF-R Cytokine Receptor Transmembrane ComplexThe SCHOOL of nature: I. Transmembrane signaling.A ligand peptide motif selected from a cancer patient is a receptor-interacting site within human interleukin-11.Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexesThe pseudokinase domain is required for suppression of basal activity of Jak2 and Jak3 tyrosine kinases and for cytokine-inducible activation of signal transduction.Three lysine residues in the common β chain of the interleukin-5 receptor are required for Janus kinase (JAK)-dependent receptor ubiquitination, endocytosis, and signalingPerspectives for the use of structural information and chemical genetics to develop inhibitors of Janus kinasesMultifarious determinants of cytokine receptor signaling specificity.Forced homo- and heterodimerization of all gp130-type receptor complexes leads to constitutive ligand-independent signaling and cytokine-independent growth.Heteromeric MAPPIT: a novel strategy to study modification-dependent protein-protein interactions in mammalian cells.The membrane-proximal region of the thrombopoietin receptor confers its high surface expression by JAK2-dependent and -independent mechanisms.Janus kinases affect thrombopoietin receptor cell surface localization and stability.Structural requirements of the extracellular to transmembrane domain junction for erythropoietin receptor function.Signal transduction by the atopy-associated human thymic stromal lymphopoietin (TSLP) receptor depends on Janus kinase function.Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation
P2860
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P2860
Orientational constraints of the gp130 intracellular juxtamembrane domain for signaling.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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name
Orientational constraints of the gp130 intracellular juxtamembrane domain for signaling.
@en
Orientational constraints of the gp130 intracellular juxtamembrane domain for signaling.
@nl
type
label
Orientational constraints of the gp130 intracellular juxtamembrane domain for signaling.
@en
Orientational constraints of the gp130 intracellular juxtamembrane domain for signaling.
@nl
prefLabel
Orientational constraints of the gp130 intracellular juxtamembrane domain for signaling.
@en
Orientational constraints of the gp130 intracellular juxtamembrane domain for signaling.
@nl
P2093
P2860
P356
P1476
Orientational constraints of the gp130 intracellular juxtamembrane domain for signaling.
@en
P2093
Claudia Stross
Heike M Hermanns
Iris Behrmann
Jens S Greiser
Peter C Heinrich
P2860
P304
26959-26965
P356
10.1074/JBC.M204113200
P407
P577
2002-05-14T00:00:00Z