Expression of the Ikaros gene family in childhood acute lymphoblastic leukaemia.
about
MicroRNAs in B cell development and malignancyGlobal genomic characterization of acute lymphoblastic leukemiaIkaros, Aiolos and Helios: transcription regulators and lymphoid malignancies.Notch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient miceA novel, non-canonical splice variant of the Ikaros gene is aberrantly expressed in B-cell lymphoproliferative disorders.Expression of Ik6 and Ik8 Isoforms and Their Association with Relapse and Death in Mexican Children with Acute Lymphoblastic LeukemiaIkaros is required to survive positive selection and to maintain clonal diversity during T-cell development in the thymus.Genome-wide profiling of genetic alterations in acute lymphoblastic leukemia: recent insights and future directions.Ikaros and leukaemia.Signaling proteins and transcription factors in normal and malignant early B cell development.Adult T-cell leukemia cells are characterized by abnormalities of Helios expression that promote T cell growth.Expression of dominant-negative Ikaros isoforms and associated genetic alterations in Chinese adult patients with leukemia.Ikaros dominant negative isoform (Ik6) induces IL-3-independent survival of murine pro-B lymphocytes by activating JAK-STAT and up-regulating Bcl-xl levels.Expression of a non-DNA-binding isoform of Helios induces T-cell lymphoma in mice.Ikaros: master of hematopoiesis, agent of leukemia.Overexpression of the Ikaros 6 isoform is restricted to t(4;11) acute lymphoblastic leukaemia in children and infants and has a role in B-cell survival.Ikaros (IKZF1) alterations and minimal residual disease at day 15 assessed by flow cytometry predict prognosis of childhood BCR/ABL-negative acute lymphoblastic leukemia.
P2860
Q26862811-87A6E471-E0C1-4E43-B231-4813FEB02BB3Q33712187-75DC2509-006D-4FFB-B632-5A861B872D9AQ34197736-3B283280-5F8B-4A6F-B248-FA0F380CDB6CQ34233443-A0BFA5C2-1D24-4E16-9B80-59F785168D08Q34846643-D70579B2-EC24-49FD-9809-32FEBA6A1EB5Q35679720-EB29A9EC-ED72-4C84-9C72-E49E5F67045BQ37215128-A70154F5-7FB5-4E8D-A18B-7C47C8AE6192Q37401075-21CD1F39-199B-4B8F-81D8-3D71DBB92DB0Q38371003-CD2B8A9B-F933-4256-88D2-E6EB0EF08B8CQ38804856-60DFFF32-A426-42A0-A294-C5A96D374B3AQ39163794-6B5AC74D-2044-4CD6-B8B4-5645B189D735Q39398490-2B56BC69-3F71-4FD3-963C-A18B7CDF390AQ39984463-740F6DE8-329F-4282-911F-E5B6E23BA8DCQ41819249-B6FB4CB7-2F02-4920-BD04-79184AC7C805Q42057738-F7522D09-BC64-4303-9C93-E78B0C253671Q44796463-B2C454E5-CB9C-41E2-BE6B-F74479868567Q54482212-EBCFD2A4-E7F9-442E-9835-8D95156B6E45
P2860
Expression of the Ikaros gene family in childhood acute lymphoblastic leukaemia.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Expression of the Ikaros gene family in childhood acute lymphoblastic leukaemia.
@en
Expression of the Ikaros gene family in childhood acute lymphoblastic leukaemia.
@nl
type
label
Expression of the Ikaros gene family in childhood acute lymphoblastic leukaemia.
@en
Expression of the Ikaros gene family in childhood acute lymphoblastic leukaemia.
@nl
prefLabel
Expression of the Ikaros gene family in childhood acute lymphoblastic leukaemia.
@en
Expression of the Ikaros gene family in childhood acute lymphoblastic leukaemia.
@nl
P2093
P2860
P1476
Expression of the Ikaros gene family in childhood acute lymphoblastic leukaemia.
@en
P2093
Akira Morimoto
Eiichi Ishii
Mami Takanashi
Shigeyoshi Hibi
Shinsaku Imashuku
Tomohito Yagi
Toshihiko Imamura
Yasuhiro Tabata
P2860
P304
P356
10.1046/J.1365-2141.2002.03487.X
P407
P577
2002-06-01T00:00:00Z