Leucine is a direct-acting nutrient signal that regulates protein synthesis in adipose tissue.
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The Emerging Role of Branched-Chain Amino Acids in Insulin Resistance and MetabolismReviewing the Effects of L-Leucine Supplementation in the Regulation of Food Intake, Energy Balance, and Glucose HomeostasisLeucine is a major regulator of muscle protein synthesis in neonatesBranched-chain amino acids in metabolic signalling and insulin resistanceEndotoxin disrupts the leucine-signaling pathway involving phosphorylation of mTOR, 4E-BP1, and S6K1 in skeletal muscleFeatures, causes and consequences of splanchnic sequestration of amino acid in old ratsA High-Protein Diet Reduces Weight Gain, Decreases Food Intake, Decreases Liver Fat Deposition, and Improves Markers of Muscle Metabolism in Obese Zucker Rats.The role of leucine and its metabolites in protein and energy metabolism.Enteral β-hydroxy-β-methylbutyrate supplementation increases protein synthesis in skeletal muscle of neonatal pigs.Leucine and protein metabolism in obese Zucker rats.Chronic heart failure reduces Akt phosphorylation in human skeletal muscle: relationship to muscle size and functionBranched-chain amino acids enhance premature senescence through mammalian target of rapamycin complex I-mediated upregulation of p21 protein.Oral leucine supplementation is sensed by the brain but neither reduces food intake nor induces an anorectic pattern of gene expression in the hypothalamus.Differential effects of long-term leucine infusion on tissue protein synthesis in neonatal pigsDifferential effect of long-term leucine supplementation on skeletal muscle and adipose tissue in old rats: an insulin signaling pathway approach.Triennial Growth Symposium: leucine acts as a nutrient signal to stimulate protein synthesis in neonatal pigsImpact of prolonged leucine supplementation on protein synthesis and lean growth in neonatal pigs.Effects of a leucine and pyridoxine-containing nutraceutical on fat oxidation, and oxidative and inflammatory stress in overweight and obese subjects.Global deletion of BCATm increases expression of skeletal muscle genes associated with protein turnoverImportant genes in the pathogenesis of 5q- syndrome and their connection with ribosomal stress and the innate immune system pathway.Glutamine and leucine provide enhanced protective immunity against mucosal infection with herpes simplex virus type 1.Leucine supplementation of a chronically restricted protein and energy diet enhances mTOR pathway activation but not muscle protein synthesis in neonatal pigs.Leucine and protein synthesis: mTOR and beyond.The sensing of essential amino acid deficiency in the anterior piriform cortex, that requires the uncharged tRNA/GCN2 pathway, is sensitive to wortmannin but not rapamycin.Amino acids, independent of insulin, attenuate skeletal muscle autophagy in neonatal pigs during endotoxemia.Integration of hormonal and nutrient signals that regulate leptin synthesis and secretionNutritional strategies for the preservation of fat free mass at high altitude.mTOR and the differentiation of mesenchymal stem cells.Leucine nutrition in animals and humans: mTOR signaling and beyond.Effects of oral branched-chain amino acids on hepatic encephalopathy and outcome in patients with liver cirrhosis.Regulation of the proteome by amino acids.Inability to replete white adipose tissue during recovery phase of sepsis is associated with increased autophagy, apoptosis, and proteasome activity.Application of a nonradioactive method of measuring protein synthesis in industrially relevant Chinese hamster ovary cells.L-leucine supplementation worsens the adiposity of already obese rats by promoting a hypothalamic pattern of gene expression that favors fat accumulation.Supplementation of essential amino acids may reduce the occurrence of infections in rehabilitation patients with brain injury.Suppressive effects of nobiletin on hyperleptinemia and colitis-related colon carcinogenesis in male ICR mice.Decreased Whole-Body Fat Mass Produced by Chronic Alcohol Consumption is Associated with Activation of S6K1-Mediated Protein Synthesis and Increased Autophagy in Epididymal White Adipose Tissue.Leucine and alpha-ketoisocaproic acid, but not norleucine, stimulate skeletal muscle protein synthesis in neonatal pigs.Metabolite profiling of antidepressant drug action reveals novel drug targets beyond monoamine elevation.Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice.
P2860
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P2860
Leucine is a direct-acting nutrient signal that regulates protein synthesis in adipose tissue.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Leucine is a direct-acting nut ...... n synthesis in adipose tissue.
@en
Leucine is a direct-acting nut ...... n synthesis in adipose tissue.
@nl
type
label
Leucine is a direct-acting nut ...... n synthesis in adipose tissue.
@en
Leucine is a direct-acting nut ...... n synthesis in adipose tissue.
@nl
prefLabel
Leucine is a direct-acting nut ...... n synthesis in adipose tissue.
@en
Leucine is a direct-acting nut ...... n synthesis in adipose tissue.
@nl
P2093
P2860
P1476
Leucine is a direct-acting nut ...... n synthesis in adipose tissue.
@en
P2093
Alain Vaval
Brian J Patson
Christopher J Lynch
Joshua Anthony
Leonard S Jefferson
Thomas C Vary
P2860
P304
P356
10.1152/AJPENDO.00084.2002
P577
2002-09-01T00:00:00Z