Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages.
about
IAN family critically regulates survival and development of T lymphocytes.TOX provides a link between calcineurin activation and CD8 lineage commitmentPhysical dissociation of the TCR-CD3 complex accompanies receptor ligationReconstitution of the subclass-specific expression of CD4 in thymocytes and peripheral T cells of transgenic mice: identification of a human CD4 enhancerGene targeting in mice: a reviewRole of the transcription factor Bcl11b in development and lymphomagenesisSubcapsular sinus macrophage fragmentation and CD169+ bleb acquisition by closely associated IL-17-committed innate-like lymphocytesAntigen recognition by autoreactive CD4⁺ thymocytes drives homeostasis of the thymic medullaAlpha-beta T cells provide protection against lethal encephalitis in the murine model of VEEV infectionKey role of T cell defects in age-related vulnerability to West Nile virusExpression of the Bcl-2 family member A1 is developmentally regulated in T cellsGut microbiota elicits a protective immune response against malaria transmissionGamma delta T cells from tolerized alpha beta T cell receptor (TCR)-deficient mice inhibit contact sensitivity-effector T cells in vivo, and their interferon-gamma production in vitroRhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte developmentThe Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signalingMetabolites from apoptotic thymocytes inhibit thymopoiesis in adenosine deaminase-deficient fetal thymic organ culturesDeletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell developmentImpairment of T cell development in deltaEF1 mutant miceIdentification and characterization of thymus LIM protein: targeted disruption reduces thymus cellularityBcl11b is required for differentiation and survival of alphabeta T lymphocytesDisruption of epithelial gamma delta T cell repertoires by mutation of the Syk tyrosine kinaseThe Bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineageThe Syk family of protein tyrosine kinases in T-cell activation and developmentIdentification of the transgenic integration site in immunodeficient tgε26 human CD3ε transgenic miceGerminal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cellsDevelopment of CD4+CD8+ thymocytes in RAG-deficient mice through a T cell receptor beta chain-independent pathwayShcA regulates late stages of T cell development and peripheral CD4+ T cell numbers.Sphingosine-1-phosphate receptor 2 is critical for follicular helper T cell retention in germinal centers.T Lymphocytes Influence the Mineralization Process of BoneT cells in mice expressing a transgenic human TCR beta chain get positively selected but cannot be activated in the periphery by signaling through TCR.Alloantibody production is regulated by CD4+ T cells' alloreactive pathway, rather than precursor frequency or Th1/Th2 differentiation.An antibiotic-responsive mouse model of fulminant ulcerative colitisColitis in transgenic and knockout animals as models of human inflammatory bowel disease.Identification of a unique population of tissue-memory CD4+ T cells in the airways after influenza infection that is dependent on the integrin VLA-1.Mast cells limit systemic bacterial dissemination but not colitis in response to Citrobacter rodentiumInterleukin 4 promotes the development of ex-Foxp3 Th2 cells during immunity to intestinal helminthsAlphabeta versus gammadelta lineage choice at the first TCR-controlled checkpointSpontaneous chronic colitis in TCR alpha-mutant mice; an experimental model of human ulcerative colitis.Control of B cell development by Ras-mediated activation of Raf.The CD3gamma chain is essential for development of both the TCRalphabeta and TCRgammadelta lineages.
P2860
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P2860
Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh-hant
name
Mutations in T-cell antigen re ...... velopment at different stages.
@en
Mutations in T-cell antigen re ...... velopment at different stages.
@nl
type
label
Mutations in T-cell antigen re ...... velopment at different stages.
@en
Mutations in T-cell antigen re ...... velopment at different stages.
@nl
prefLabel
Mutations in T-cell antigen re ...... velopment at different stages.
@en
Mutations in T-cell antigen re ...... velopment at different stages.
@nl
P2093
P356
P1433
P1476
Mutations in T-cell antigen re ...... velopment at different stages.
@en
P2093
Iacomini J
Ichikawa Y
Jaenisch R
Lafaille JJ
Mombaerts P
Rudnicki MA
P2888
P304
P356
10.1038/360225A0
P407
P577
1992-11-01T00:00:00Z
P5875
P6179
1011545272