Altered processing of the neurotensin/neuromedin N precursor in PC2 knock down mice: a biochemical and immunohistochemical study.
about
Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR siteIn vivo evidence that furin from hepatocytes inactivates PCSK9Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice.Deficiency of prohormone convertase dPC2 (AMONTILLADO) results in impaired production of bioactive neuropeptide hormones in Drosophila.Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects.Identification of proprotein convertase substrates using genome-wide expression correlation analysis.What lies ahead for the proprotein convertases?Deletion of the gene encoding proprotein convertase 5/6 causes early embryonic lethality in the mouseThe molecular and structural characterization of two vitellogenins from the free-living nematode Oscheius tipulae.Ablation of the glucagon receptor gene increases fetal lethality and produces alterations in islet development and maturationFurin is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10.Cathepsin L and Arg/Lys aminopeptidase: a distinct prohormone processing pathway for the biosynthesis of peptide neurotransmitters and hormones.Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells.The role of neurotensin in central nervous system pathophysiology: what is the evidence?Unique neuronal functions of cathepsin L and cathepsin B in secretory vesicles: biosynthesis of peptides in neurotransmission and neurodegenerative disease.Genetics of the first seven proprotein convertase enzymes in health and disease.Proprotein convertase subtilisin/kexin type 7 (PCSK7) is essential for the zebrafish development and bioavailability of transforming growth factor β1a (TGFβ1a).Internalization of proprotein convertase PC7 from plasma membrane is mediated by a novel motif.Disruption of proprotein convertase 1/3 (PC1/3) expression in mice causes innate immune defects and uncontrolled cytokine secretion.The proprotein convertase PC7: unique zymogen activation and trafficking pathways.Proprotein convertase PC7 enhances the activation of the EGF receptor pathway through processing of the EGF precursor.Genetic deficiency for proprotein convertase subtilisin/kexin type 2 in mice is associated with decreased adiposity and protection from dietary fat-induced body weight gain.
P2860
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P2860
Altered processing of the neurotensin/neuromedin N precursor in PC2 knock down mice: a biochemical and immunohistochemical study.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年學術文章
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name
Altered processing of the neur ...... and immunohistochemical study.
@en
Altered processing of the neur ...... and immunohistochemical study.
@nl
type
label
Altered processing of the neur ...... and immunohistochemical study.
@en
Altered processing of the neur ...... and immunohistochemical study.
@nl
prefLabel
Altered processing of the neur ...... and immunohistochemical study.
@en
Altered processing of the neur ...... and immunohistochemical study.
@nl
P2093
P50
P1476
Altered processing of the neur ...... and immunohistochemical study.
@en
P2093
Alain Beaudet
Gilles Croissandeau
Patrick Kitabgi
Pierre Villeneuve
P304
P356
10.1046/J.1471-4159.2002.00988.X
P407
P577
2002-08-01T00:00:00Z