Inducible lung-specific urokinase expression reduces fibrosis and mortality after lung injury in mice. - Wikidata - wikimedia - TriplyDB

Inducible lung-specific urokinase expression reduces fibrosis and mortality after lung injury in mice.

Inducible lung-specific urokinase expression reduces fibrosis and mortality after lung injury in mice.

http://www.wikidata.org/entity/Q44176958

about

Urokinase-type plasminogen activator receptor (uPAR) ligation induces a raft-localized integrin signaling switch that mediates the hypermotile phenotype of fibrotic fibroblasts Pathogenetic mechanisms in usual interstitial pneumonia/idiopathic pulmonary fibrosis.Doxycycline attenuated pulmonary fibrosis induced by bleomycin in mice.Role of the urokinase-fibrinolytic system in epithelial-mesenchymal transition during lung injury.Thrombin-activatable fibrinolysis inhibitor deficiency attenuates bleomycin-induced lung fibrosis.The plasminogen activation system reduces fibrosis in the lung by a hepatocyte growth factor-dependent mechanism.Macrophage-specific expression of urokinase-type plasminogen activator promotes skeletal muscle regeneration Urokinase and its receptors in chronic kidney disease.Proteolytic regulation of epithelial sodium channels by urokinase plasminogen activator: cutting edge and cleavage sites.Plasminogen activator inhibitor-1 suppresses profibrotic responses in fibroblasts from fibrotic lungs Disorders of lung matrix remodeling.Reduction in fibrotic tissue formation in mice genetically deficient in plasminogen activator inhibitor-1.Role of epithelial sodium channels in the regulation of lung fluid homeostasis Epithelial-mesenchymal interactions in pulmonary fibrosis.Idiopathic pulmonary fibrosis : new concepts in pathogenesis and implications for drug therapy PAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury.Leukocyte cell surface proteinases: regulation of expression, functions, and mechanisms of surface localization.Oxidative stress, plasminogen activator inhibitor 1, and lung fibrosis Regulation of lung injury and fibrosis by p53-mediated changes in urokinase and plasminogen activator inhibitor-1.A cohort study of mortality predictors in patients with acute exacerbation of chronic fibrosing interstitial pneumonia Advances in mechanisms of repair and remodelling in acute lung injury.Expression of the reverse tetracycline-transactivator gene causes emphysema-like changes in mice.Bugs in the system.A review of pulmonary coagulopathy in acute lung injury, acute respiratory distress syndrome and pneumonia.The pathogenesis of idiopathic pulmonary fibrosis.Therapeutic modulation of coagulation and fibrinolysis in acute lung injury and the acute respiratory distress syndrome Gene expression profiling in patients with chronic obstructive pulmonary disease and lung cancer.Raised protein levels and altered cellular expression of factor VII activating protease (FSAP) in the lungs of patients with acute respiratory distress syndrome (ARDS).The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in humans and mice.Induction of tissue factor by urokinase in lung epithelial cells and in the lungs.Regulation of epithelial sodium channels in urokinase plasminogen activator deficiency Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis Glutathione restores collagen degradation in TGF-beta-treated fibroblasts by blocking plasminogen activator inhibitor-1 expression and activating plasminogen.Plasminogen-mediated activation and release of hepatocyte growth factor from extracellular matrix.Plasminogen activation induced pericellular fibronectin proteolysis promotes fibroblast apoptosis.Increased expression of protease nexin-1 in fibroblasts during idiopathic pulmonary fibrosis regulates thrombin activity and fibronectin expression.Fibrinolysis in LPS-induced chronic airway disease.p53 and miR-34a Feedback Promotes Lung Epithelial Injury and Pulmonary Fibrosis.Fibrinolytic system related to pulmonary arterial pressure and lung function of patients with idiopathic pulmonary fibrosis.Mice deficient in plasminogen activator inhibitor-1 have improved skeletal muscle regeneration.

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P2860

Inducible lung-specific urokinase expression reduces fibrosis and mortality after lung injury in mice.

http://www.wikidata.org/entity/Q44176958

description

2002 nî lūn-bûn

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

@zh-my

2002年学术文章

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2002年學術文章

@yue

2002年學術文章

@zh-hant

name

Inducible lung-specific urokin ...... ity after lung injury in mice.

@en

Inducible lung-specific urokin ...... ity after lung injury in mice.

@nl

type

label

Inducible lung-specific urokin ...... ity after lung injury in mice.

@en

Inducible lung-specific urokin ...... ity after lung injury in mice.

@nl

prefLabel

Inducible lung-specific urokin ...... ity after lung injury in mice.

@en

Inducible lung-specific urokin ...... ity after lung injury in mice.

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AJPLUNG.00049.2002

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American Journal of Physiology - Lung Cellular and Molecular Physiology

P1476

Inducible lung-specific urokin ...... ity after lung injury in mice.

@en

P2093

Anjali Patwardhan

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Kerstin E Hanson

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Natalya Subbotina

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Noboru Hattori

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Richard H Simon

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Thomas H Sisson

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P2860

The development of bleomycin-induced pulmonary fibrosis in mice deficient for components of the fibrinolytic system

Changes in procoagulant and fibrinolytic gene expression during bleomycin-induced lung injury in the mouse.

Bleomycin-induced pulmonary fibrosis in fibrinogen-null mice.

Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice.

Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene.

Regulated overexpression of interleukin 11 in the lung. Use to dissociate development-dependent and -independent phenotypes

Participation of urokinase-type plasminogen activator receptor in the clearance of fibrin from the lung.

Upregulation of fibrinolysis by adenovirus-mediated transfer of urokinase-type plasminogen activator genes to lung cells in vitro and in vivo.

Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1).

uPA/plasmin system-mediated MMP-9 activation is implicated in bronchial epithelial cell migration.

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L1023-32

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10.1152/AJPLUNG.00049.2002

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5

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11084436

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12376355

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