Protein kinase C stimulates the acid-sensing ion channel ASIC2a via the PDZ domain-containing protein PICK1. - Wikidata - wikimedia - TriplyDB

Protein kinase C stimulates the acid-sensing ion channel ASIC2a via the PDZ domain-containing protein PICK1.

Protein kinase C stimulates the acid-sensing ion channel ASIC2a via the PDZ domain-containing protein PICK1.

http://www.wikidata.org/entity/Q44193829

about

The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a cAMP-dependent protein kinase phosphorylation of the acid-sensing ion channel-1 regulates its binding to the protein interacting with C-kinase-1 Parkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channels Acid-sensing ion channels in pain and disease.Regulation of TGF-β Signal Transduction Syntabulin regulates the trafficking of PICK1-containing vesicles in neurons.A stomatin dimer modulates the activity of acid-sensing ion channels Nociceptors in cardiovascular functions: complex interplay as a result of cyclooxygenase inhibition Annexin II light chain p11 promotes functional expression of acid-sensing ion channel ASIC1a PSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+- gated current Stomatin modulates gating of acid-sensing ion channels Molecular determinants for the complex binding specificity of the PDZ domain in PICK1 ASIC2b-dependent regulation of ASIC3, an essential acid-sensing ion channel subunit in sensory neurons via the partner protein PICK-1 ASIC2 subunits target acid-sensing ion channels to the synapse via an association with PSD-95 Physical interaction between the serotonin transporter and neuronal nitric oxide synthase underlies reciprocal modulation of their activity Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/discs-large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands.ASIC2 subunits facilitate expression at the cell surface and confer regulation by PSD-95.Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1.Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1 Protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala.Extracellular acidosis activates ASIC-like channels in freshly isolated cerebral artery smooth muscle cells Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity.Acid-sensing ion channels: trafficking and synaptic function.PDZ binding to the BAR domain of PICK1 is elucidated by coarse-grained molecular dynamics.PICK1 regulates the trafficking of ASIC1a and acidotoxicity in a BAR domain lipid binding-dependent manner.A kinase-anchoring protein 150 and calcineurin are involved in regulation of acid-sensing ion channels ASIC1a and ASIC2a.Regulation of ASIC activity by ASIC4--new insights into ASIC channel function revealed by a yeast two-hybrid assay.Heteromeric acid-sensing ion channels (ASICs) composed of ASIC2b and ASIC1a display novel channel properties and contribute to acidosis-induced neuronal death Serine 77 in the PDZ domain of PICK1 is a protein kinase Cα phosphorylation site regulated by lipid membrane binding.ENaCs and ASICs as therapeutic targets.Making protein interactions druggable: targeting PDZ domains.Acid-sensing ion channels: trafficking and pathophysiology.Prokineticin 2 potentiates acid-sensing ion channel activity in rat dorsal root ganglion neurons.Down-regulation of ASICs current and the calcium transients by disrupting PICK1 protects primary cultured mouse cortical neurons from OGD-Rep insults PICK1 promotes caveolin-dependent degradation of TGF-β type I receptor.Membrane localization is critical for activation of the PICK1 BAR domain.Protein kinase C in pain: involvement of multiple isoforms Functional modulation of the glutamate transporter variant GLT1b by the PDZ domain protein PICK1.Two PKC consensus sites on human acid-sensing ion channel 1b differentially regulate its function.PICK1/calcineurin suppress ASIC1-mediated Ca2+ entry in rat pulmonary arterial smooth muscle cells.

P2860

Q24544187-44FF8B4A-0037-4450-B76D-0CB2B56C1609 Q24550782-B73213CD-0269-4157-9B99-9FBAA58EB858 Q24679424-25C08D17-CA95-446D-B0DB-CD471B8A693B Q26829975-211A0940-190B-4E5A-A664-4B79B849726E Q26996826-E0B1D366-A578-4E5E-97AB-53120EC6B4A1 Q27349717-8E5F4736-8FC0-45E7-9E02-01CDD8C57830 Q27671013-33EA96CB-428C-44BB-8186-B3225047A45B Q28200171-0FE14FC5-C0E8-48AE-BBED-FA0F29B66AC4 Q28272902-3FAF65BD-53BC-4672-B28C-3833BEFEE4AD Q28277696-85A575BE-FD1B-461F-AEAD-33975019B7D6 Q28286776-C84AD9D3-E8F8-4B9A-93EC-803D5148C6B0 Q28569924-A819CB5A-B4BD-4FA8-9F6B-87E32BBB72F7 Q28584265-884A805D-37CA-4500-ABF0-346989A3B4CE Q28592489-C5B2392E-1C34-4EE0-81CF-0CA94E25F82E Q28593956-6959A943-EB76-4A39-B24C-E6905A232907 Q30364686-9ADEEAE4-535A-4E2E-9282-1E6AFD191BC7 Q31156844-8622F86E-E475-438C-A73B-FFD1A8CFEC78 Q33313937-8CAFD6AD-AA35-43F7-93E8-CDB8B522B413 Q33644620-54D37932-2BEA-4F2C-B55A-191D66E6BB5C Q33790161-CC3F248F-BCE6-4906-BAA5-E4925A74B554 Q33840385-D18491B1-B08A-4758-AC8A-65266DF832F3 Q33969340-63518BA2-1D08-46BA-BB2E-392197DD5676 Q34320487-3AA4F06D-01F8-4F5A-87CF-7BC5034E98AF Q34432049-DAD07B04-8DDC-4917-A39E-7EA82C295E6A Q34477846-DB59FDFB-00D1-451C-BCC0-2CEEC016E893 Q34634258-A2876AD1-5181-4F16-9B1B-C517F021C743 Q34801941-43C35A0C-A9F3-4DB6-B1D5-FF7ACEB087AF Q35178328-6FEEFA0A-5853-4398-9CB8-3085F58C2C43 Q35852753-A3DC78CD-EDB7-4E9E-92B3-54F0A19E8BCC Q35900722-B06DADB6-EDC4-467F-9454-DDE11AD03843 Q35968398-51C1BC16-E956-4842-BCA4-4FCC663EA417 Q36124901-209F3415-D2EF-402F-9BBD-065B0EB8A163 Q36146292-1BF1F602-CC2E-43CF-A7E2-0F832ED2D7D1 Q36261342-3F2C00EB-5341-4FD8-8EA9-C2F83F5966C0 Q36294546-C0B50621-7EC2-4AF8-89EE-A9CDD6BF6D49 Q36755823-DDD5BAAD-FDBE-40B9-8349-F91F67E5F025 Q36840305-3471C26A-96D0-4062-81EF-FF12CE38DE77 Q37012384-4C3A5A90-D6FF-40DC-9D71-B975ED68105E Q37100006-7B58FD52-97E6-4E46-904A-A2AC2DF10549 Q37148774-F3D28F66-A638-44F6-98DD-1561AF816EDE

P2860

Protein kinase C stimulates the acid-sensing ion channel ASIC2a via the PDZ domain-containing protein PICK1.

http://www.wikidata.org/entity/Q44193829

description

2002 nî lūn-bûn

@nan

2002年の論文

@ja

2002年学术文章

@wuu

2002年学术文章

@zh

2002年学术文章

@zh-cn

2002年学术文章

@zh-hans

2002年学术文章

@zh-my

2002年学术文章

@zh-sg

2002年學術文章

@yue

2002年學術文章

@zh-hant

name

Protein kinase C stimulates th ...... main-containing protein PICK1.

@en

Protein kinase C stimulates th ...... main-containing protein PICK1.

@nl

type

label

Protein kinase C stimulates th ...... main-containing protein PICK1.

@en

Protein kinase C stimulates th ...... main-containing protein PICK1.

@nl

prefLabel

Protein kinase C stimulates th ...... main-containing protein PICK1.

@en

Protein kinase C stimulates th ...... main-containing protein PICK1.

@nl

P1433

Q44193829-46F24B32-8FF1-4A08-8A79-FE05D8994A6A

P1476

Q44193829-7632DA6D-F78D-4D7A-A072-BD3D1A214B05

P2093

Q44193829-1EB7DB86-BBAC-47B4-BAA6-FBACB1855B27

Q44193829-98F7C72D-345D-48BA-9A1B-A0A018447678

Q44193829-A3A02C54-145B-45A7-9A4C-8F52162F8861

P2860

Q44193829-051AAC54-ABEA-4308-8E03-894868E43C1A

Q44193829-0CC2ED51-3EDD-4ECD-A925-16C416B97365

Q44193829-0D1DF54C-25D5-47A8-A33D-C9AC3003B858

Q44193829-0F3502F7-83AE-46C8-99E4-9BEF24AA2BEC

Q44193829-19AB659C-80B8-471F-8E6A-84C9BE9D64E3

Q44193829-1BD2F61B-3297-48B6-951B-0660B0A58184

Q44193829-1C386626-06EC-40E9-8642-0EC2BA395F64

Q44193829-1E392D8D-9827-4EF9-A62A-3BDDF3FBD87A

Q44193829-1EC478A6-C1EA-4CAD-B528-C4372279EB6D

Q44193829-1EFF8666-565A-4A0E-91DF-5DACC426A403

P304

Q44193829-B00A4F82-DE7E-4FAC-A4DC-CB63D40B5BF4

P31

Q44193829-F7FA93CF-64DA-4E02-90CE-1EC173D4ECC7

P356

Q44193829-4E9D21DA-7789-40B5-B93F-A5D5EDEA6CEF

P407

Q44193829-7E721106-EC3D-40A3-92E4-75C2D6BCDF21

P433

Q44193829-B3354DA7-A159-4F65-AB68-4A34F7EDC29B

P478

Q44193829-0B9714D3-CD73-43C9-BBE0-C1BB4EB0AD7D

P50

Q44193829-DB93BCED-B328-45E7-B66C-FCFE962CBD6B

Q44193829-DCEA37A9-BE85-4581-AD62-A34E21DC2D64

Q44193829-F834A5BD-6E41-43B6-A18A-C35ED6002AD7

P577

Q44193829-706C3C8C-C818-4AF9-9C2E-334E9EBD2D2E

P5875

Q44193829-4B1CE6E9-3C43-4904-A230-742BED8251BB

P698

Q44193829-D3B9A62C-F4F6-4CD1-8B6A-632F2356999F

P356

P1433

Journal of Biological Chemistry

P1476

Protein kinase C stimulates th ...... omain-containing protein PICK1

@en

P2093

Anne Baron

http://www.w3.org/2001/XMLSchema#string

Michel Lazdunski

http://www.w3.org/2001/XMLSchema#string

Nicolas Voilley

http://www.w3.org/2001/XMLSchema#string

P2860

A new member of acid-sensing ion channels from pituitary gland

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1

Interaction of the synaptic protein PICK1 (protein interacting with C kinase 1) with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1) and ASIC (acid-sensing ion channel)

The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory

Cloning and expression of a novel human brain Na+ channel

Functional implications of the localization and activity of acid-sensitive channels in rat peripheral nervous system

Differential roles for NSF and GRIP/ABP in AMPA receptor cycling.

A mammalian two pore domain mechano-gated S-like K+ channel

Acid-sensing ion channel 3 matches the acid-gated current in cardiac ischemia-sensing neurons

P304

50463-50468

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M208848200

http://www.w3.org/2001/XMLSchema#string

P407

P433

52

http://www.w3.org/2001/XMLSchema#string

P478

277

http://www.w3.org/2001/XMLSchema#string

P50

Eric Lingueglia

P577

2002-10-23T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

11064988

http://www.w3.org/2001/XMLSchema#string

P698

12399460

http://www.w3.org/2001/XMLSchema#string