Repair of dihydrouracil supported by base excision repair in mNTH1 knock-out cell extracts.
about
The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activityInduction of the human oxidized base-specific DNA glycosylase NEIL1 by reactive oxygen speciesDefective repair of oxidative base lesions by the DNA glycosylase Nth1 associates with multiple telomere defects.Commentary: DNA base excision repair defects in human pathologies.Regulation of DNA glycosylases and their role in limiting disease.Stereoselective excision of thymine glycol from oxidatively damaged DNA.Increased ROS generation in subsets of OGG1 knockout fibroblast cellsOxidative DNA damage in disease--insights gained from base excision repair glycosylase-deficient mouse models.The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway.Compromised incision of oxidized pyrimidines in liver mitochondria of mice deficient in NTH1 and OGG1 glycosylases.Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas.NTH1 is a new target for ubiquitylation-dependent regulation by TRIM26 required for the cellular response to oxidative stress.
P2860
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P2860
Repair of dihydrouracil supported by base excision repair in mNTH1 knock-out cell extracts.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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name
Repair of dihydrouracil suppor ...... mNTH1 knock-out cell extracts.
@en
Repair of dihydrouracil suppor ...... mNTH1 knock-out cell extracts.
@nl
type
label
Repair of dihydrouracil suppor ...... mNTH1 knock-out cell extracts.
@en
Repair of dihydrouracil suppor ...... mNTH1 knock-out cell extracts.
@nl
prefLabel
Repair of dihydrouracil suppor ...... mNTH1 knock-out cell extracts.
@en
Repair of dihydrouracil suppor ...... mNTH1 knock-out cell extracts.
@nl
P2860
P356
P1476
Repair of dihydrouracil suppor ...... mNTH1 knock-out cell extracts
@en
P2093
Grigory L Dianov
P2860
P304
50487-50490
P356
10.1074/JBC.M208153200
P407
P577
2002-10-24T00:00:00Z