Site-specific phosphorylation differentiates active from inactive forms of the human T-cell leukemia virus type 1 Tax oncoprotein. - Wikidata - wikimedia - TriplyDB

Site-specific phosphorylation differentiates active from inactive forms of the human T-cell leukemia virus type 1 Tax oncoprotein.

Site-specific phosphorylation differentiates active from inactive forms of the human T-cell leukemia virus type 1 Tax oncoprotein.

http://www.wikidata.org/entity/Q44199158

about

The HTLV-1 Tax interactome Roles of HTLV-1 basic Zip Factor (HBZ) in Viral Chronicity and Leukemic Transformation. Potential New Therapeutic Approaches to Prevent and Treat HTLV-1-Related Diseases Tax-1 and Tax-2 similarities and differences: focus on post-translational modifications and NF-κB activation.Acetylation of the human T-cell leukemia virus type 1 Tax oncoprotein by p300 promotes activation of the NF-kappaB pathway.The viral oncoprotein tax sequesters DNA damage response factors by tethering MDC1 to chromatin.HTLV-1 tax-induced rapid senescence is driven by the transcriptional activity of NF-κB and depends on chronically activated IKKα and p65/RelA.Role of post-translational modifications of HTLV-1 Tax in NF-κB activation.Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling Human T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesis Move or die: the fate of the Tax oncoprotein of HTLV-1.Identification and characterization of HTLV-1 HBZ post-translational modifications.The Sumo-targeted ubiquitin ligase RNF4 regulates the localization and function of the HTLV-1 oncoprotein Tax.Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy.Ubiquitination of HTLV-I Tax in response to DNA damage regulates nuclear complex formation and nuclear export.Nuclear trafficking of the human cytomegalovirus pp71 (ppUL82) tegument protein.Physical and in silico approaches identify DNA-PK in a Tax DNA-damage response interactome.HTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinase Acetylation at lysine 346 controls the transforming activity of the HTLV-1 Tax oncoprotein in the Rat-1 fibroblast model Peptidylproline cis-trans-isomerase Pin1 interacts with human T-cell leukemia virus type 1 tax and modulates its activation of NF-kappaB Dimerization and a novel Tax speckled structure localization signal are required for Tax nuclear localization.Site-specific phosphorylation regulates human T-cell leukemia virus type 2 Rex function in vivo.HSP90 protects the human T-cell leukemia virus type 1 (HTLV-1) tax oncoprotein from proteasomal degradation to support NF-κB activation and HTLV-1 replication Phosphorylation regulates human T-cell leukemia virus type 1 Rex function.HTLV gene regulation: because size matters, transcription is not enough.Intracellular localization and cellular factors interaction of HTLV-1 and HTLV-2 Tax proteins: similarities and functional differences.The MHC-II transactivator CIITA, a restriction factor against oncogenic HTLV-1 and HTLV-2 retroviruses: similarities and differences in the inhibition of Tax-1 and Tax-2 viral transactivators.Human T-lymphotropic virus proteins and post-translational modification pathways Tax posttranslational modifications and interaction with calreticulin in MT-2 cells and human peripheral blood mononuclear cells of human T cell lymphotropic virus type-I-associated myelopathy/tropical spastic paraparesis patients.Group I p21-activated kinases facilitate Tax-mediated transcriptional activation of the human T-cell leukemia virus type 1 long terminal repeats.Human T-cell leukemia virus type 1 Tax oncoprotein prevents DNA damage-induced chromatin egress of hyperphosphorylated Chk2.Human T cell leukemia virus type 2 tax-mediated NF-κB activation involves a mechanism independent of Tax conjugation to ubiquitin and SUMO.

P2860

Q21093224-02B99C8D-00FC-4D56-8828-D55447702554 Q26774352-39E564E3-70CD-4DD3-BE4F-C4068C447224 Q30353061-45840950-A831-43CD-9D90-0A1280CDDA64 Q33709523-7DEA475B-8A21-41E2-A69D-401E430C5896 Q34236779-C1C47460-D2C3-4B71-AE44-E9EB5CB91D20 Q34319511-B606F3D5-BB0C-4D8C-A9BA-1D23C0E99E8F Q34878458-9BF6F17B-060D-4487-8A6B-1CADCD307041 Q35077552-1D320617-FA2F-4CB1-AED3-E58D29A7D599 Q35090534-48E2F24A-9EA4-4142-A59C-EFE1138CE806 Q35261367-9706169B-1125-449E-A412-153A46E6589A Q35412479-87B0DE3C-EDF1-4814-8DA5-A46038B15156 Q35750342-978B9A74-67B2-465E-B419-31B61C5FD96E Q36147455-FC9159B1-DD1F-4C28-83A2-07EB0377D659 Q36447062-E52A88BD-2392-40C9-8CEB-DDDDC5AFB6BC Q36766049-33AB44DF-5D3B-4E77-8757-C7A1BA27D737 Q36957291-8A2281C0-EF25-4BAE-9146-1B1902B199DF Q37021560-96CD12DC-38DD-49D2-8107-FE6796CD3E92 Q37071800-67D8FBC7-6C0F-40A4-B47D-F6681CF9BB1F Q37127860-546D6549-F35F-4B6E-AD38-C83745FE15A2 Q37191904-569F494C-61D4-4C1F-A89C-C679B68CDE07 Q37333854-933FD728-6A01-401C-A51D-5CBA1EB3B6B2 Q37336808-CBC64A83-2BDC-4FCB-9B49-0DA4F722C834 Q37429560-98634545-D191-43C6-8EEA-72D140A1328D Q37470581-46D9CADF-17A6-423A-9A44-A2A5563355B7 Q37945226-56EBEBC8-E7F8-460E-9956-2DAB7C16CE25 Q38132389-6FF06EEE-AF18-4D04-9943-72FCAC432D83 Q38156859-07E7EF32-AA28-4A48-9A07-1166B4301497 Q38623545-7D4A527F-C8C0-42C7-B41E-5BE3677A7D40 Q38937779-DC59CE2E-9507-4D4E-BD53-C5139F2AE680 Q40094179-8FF75500-BAB1-40B0-B736-76A9B99BEA2B Q41881538-21D4F506-8440-4D1B-A39A-12D23A6948F0

P2860

Site-specific phosphorylation differentiates active from inactive forms of the human T-cell leukemia virus type 1 Tax oncoprotein.

http://www.wikidata.org/entity/Q44199158

description

2006 nî lūn-bûn

@nan

2006年の論文

@ja

2006年学术文章

@wuu

2006年学术文章

@zh

2006年学术文章

@zh-cn

2006年学术文章

@zh-hans

2006年学术文章

@zh-my

2006年学术文章

@zh-sg

2006年學術文章

@yue

2006年學術文章

@zh-hant

name

Site-specific phosphorylation ...... virus type 1 Tax oncoprotein.

@en

Site-specific phosphorylation ...... virus type 1 Tax oncoprotein.

@nl

type

label

Site-specific phosphorylation ...... virus type 1 Tax oncoprotein.

@en

Site-specific phosphorylation ...... virus type 1 Tax oncoprotein.

@nl

prefLabel

Site-specific phosphorylation ...... virus type 1 Tax oncoprotein.

@en

Site-specific phosphorylation ...... virus type 1 Tax oncoprotein.

@nl

P1433

Q44199158-E59DEC5C-8A15-4FC3-B9EB-807907BEEBF4

P1476

Q44199158-2D18FDAA-2F68-4198-B083-844BD0DCE388

P2093

Q44199158-0ECEC478-E335-4712-B639-6ED92D4F3192

Q44199158-4C31DCB8-9E96-47D2-B78F-9760DB61C3AA

Q44199158-CA0D5D7C-922A-4398-8F63-CF9AE12F456D

Q44199158-CD4E1F04-972D-4878-94DA-15FF93EFFA95

P2860

Q44199158-051F305C-334B-49C9-A605-160F5FD055E6

Q44199158-0ED8AA9B-29ED-4715-B369-B5D9ECAE1F78

Q44199158-134965F8-554F-428C-9EFA-5E096F869341

Q44199158-13699B58-47B6-42FE-A830-AD93744430E3

Q44199158-13932684-088B-451A-93B3-F5FA13CE131F

Q44199158-141061E7-4CFA-44B7-BED6-A0DA051D3D4E

Q44199158-1583E5D0-62CB-4F40-B31C-2B3B2096B348

Q44199158-24B49793-66A2-44B0-B5DA-CB33315886F5

Q44199158-2B4D40E7-C652-46D7-B858-1080F346259B

Q44199158-386A551E-5925-45B9-BF63-97B1440A45E5

P304

Q44199158-ED450A73-4AD2-4769-9B94-C221520EEB3E

P31

Q44199158-779DDF00-0E89-4CD2-A37D-35DD88E2EB0C

P356

Q44199158-2480504D-B1B7-4A10-B673-29A720BCFCF8

P407

Q44199158-797716DE-A38B-42E2-ABA9-44D3E3F1E986

P433

Q44199158-AB4F32FE-D89D-4993-9AD8-A96FF85B039F

P478

Q44199158-2CF51D1A-2C99-4B8B-BE5F-BE3E41A05FA1

P577

Q44199158-4E8C594E-BD5D-41F9-A79F-EF027F4E6681

P698

Q44199158-D4C3581E-7B93-4C6E-B1D6-4F328B177BD8

P921

Q44199158-0F4113AE-DE92-4A9A-AF2E-07031F973B59

Q44199158-1836BD38-E3D0-4713-9D0E-C4FEA63207DD

P356

P1433

Journal of Biological Chemistry

P1476

Site-specific phosphorylation ...... virus type 1 Tax oncoprotein.

@en

P2093

Kimberly A Fryrear

http://www.w3.org/2001/XMLSchema#string

Michael D Ward

http://www.w3.org/2001/XMLSchema#string

O John Semmes

http://www.w3.org/2001/XMLSchema#string

Sarah S Durkin

http://www.w3.org/2001/XMLSchema#string

P2860

The C-terminus of the HTLV-1 Tax oncoprotein mediates interaction with the PDZ domain of cellular proteins

Human T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL)

Ku protein as a potential human T-cell leukemia virus type 1 (HTLV-1) Tax target in clastogenic chromosomal instability of mammalian cells

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

Human T-cell leukemia virus type 1 Tax shuttles between functionally discrete subcellular targets.

cAMP-dependent phosphorylation and inactivation of yeast transcription factor ADR1 does not affect DNA binding.

An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300

Molecular interactions involved in the transactivation of the human T-cell leukemia virus type 1 promoter mediated by Tax and CREB-2 (ATF-4).

Tax ubiquitylation and sumoylation control critical cytoplasmic and nuclear steps of NF-kappaB activation.

Regulation of transcription factor function by phosphorylation.

P304

31705-31712

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M607011200

http://www.w3.org/2001/XMLSchema#string

P407

P433

42

http://www.w3.org/2001/XMLSchema#string

P478

281

http://www.w3.org/2001/XMLSchema#string

P577

2006-08-21T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

16923801

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation