Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia.
about
The reduced folate carrier (SLC19A1) c.80G>A polymorphism is associated with red cell folate concentrations among womenPharmacogenomics in Pediatric Oncology: Review of Gene-Drug Associations for Clinical UsePharmacogenetics predictive of response and toxicity in acute lymphoblastic leukemia therapyReduced folate carrier and methylenetetrahydrofolate reductase gene polymorphisms: associations with clinical outcome in childhood acute lymphoblastic leukemiaPolymorphisms of the vincristine pathway and response to treatment in children with childhood acute lymphoblastic leukemiaPolymorphisms of selected xenobiotic genes contribute to the development of papillary thyroid cancer susceptibility in Middle Eastern populationAssociation of genetic polymorphism in the folate metabolic pathway with methotrexate pharmacokinetics and toxicity in childhood acute lymphoblastic leukaemia and malignant lymphoma.Effects of methylenetetrahydrofolate reductase gene polymorphisms on toxicities during consolidation therapy in pediatric acute lymphoblastic leukemia in a Chinese population.Polymorphisms in methotrexate transporters and their relationship to plasma methotrexate levels, toxicity of high-dose methotrexate, and outcome of pediatric acute lymphoblastic leukemia.The association of reduced folate carrier 80G>A polymorphism to outcome in childhood acute lymphoblastic leukemia interacts with chromosome 21 copy numberUrinary coproporphyrin I/(I + III) ratio as a surrogate for MRP2 or other transporter activities involved in methotrexate clearance.SLC19A1 pharmacogenomics summary.Geographical and ethnic distribution of single nucleotide polymorphisms within genes of the folate/homocysteine pathway metabolismOld drugs, old problems: where do we stand in prediction of rheumatoid arthritis responsiveness to methotrexate and other synthetic DMARDs?Influence of polymorphisms within the methotrexate pathway genes on the toxicity and efficacy of methotrexate in patients with juvenile idiopathic arthritis.Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues.PharmGKB summary: methotrexate pathway.RFC1 80G>A is a genetic determinant of methotrexate efficacy in rheumatoid arthritis: a human genome epidemiologic review and meta-analysis of observational studies.What is next in pharmacogenomics? Translating it to clinical practice.Pharmacogenetic determinants of outcome in acute lymphoblastic leukaemia.Ancestry and pharmacogenetics of antileukemic drug toxicityPharmacogenetics of methotrexate.Contribution of tumoral and host solute carriers to clinical drug response.The RFC1 80G>A, among Common One-Carbon Polymorphisms, Relates to Survival Rate According to DNA Global Methylation in Primary Liver Cancers.Sarcomas and pharmacogenetics.CCND1 G870A polymorphism is associated with toxicity of methotrexate in childhood acute lymphoblastic leukemiaPharmacogenetics of folate-related drug targets in cancer treatment.Folate during antifolate chemotherapy: what we know... and do not know.Acute lymphoblastic leukaemia: a model for the pharmacogenomics of cancer therapy.Review article: interactions between genotype and response to therapy in inflammatory bowel diseases.Influence of genetic polymorphisms in the folate pathway on toxicity after high-dose methotrexate treatment in pediatric osteosarcomaPharmacogenetics of acute lymphoblastic leukemia treatment response.The genetic architecture of methotrexate toxicity is similar in Drosophila melanogaster and humans.Association of germline genetic variants in RFC, IL15 and VDR genes with minimal residual disease in pediatric B-cell precursor ALL.An update on methotrexate pharmacogenetics in rheumatoid arthritis.Pharmacogenetics of Crohn's disease.Gene polymorphisms in folate metabolizing enzymes in adult acute lymphoblastic leukemia: effects on methotrexate-related toxicity and survival.Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects.Genetic and epigenomic footprints of folate.Pharmacogenomics in the treatment of inflammatory bowel disease.
P2860
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P2860
Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Polymorphism G80A in the reduc ...... acute lymphoblastic leukemia.
@en
Polymorphism G80A in the reduc ...... acute lymphoblastic leukemia.
@nl
type
label
Polymorphism G80A in the reduc ...... acute lymphoblastic leukemia.
@en
Polymorphism G80A in the reduc ...... acute lymphoblastic leukemia.
@nl
prefLabel
Polymorphism G80A in the reduc ...... acute lymphoblastic leukemia.
@en
Polymorphism G80A in the reduc ...... acute lymphoblastic leukemia.
@nl
P2093
P1433
P1476
Polymorphism G80A in the reduc ...... acute lymphoblastic leukemia.
@en
P2093
Albert Moghrabi
Caroline Laverdière
Irina Costea
Maja Krajinovic
Sonia Chiasson
P304
P356
10.1182/BLOOD.V100.10.3832
P407
P577
2002-11-01T00:00:00Z