Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits.
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RANK-RANKL signalling in cancerGene-Lifestyle Interactions in Complex Diseases: Design and Description of the GLACIER and VIKING StudiesLGR4 Is a Direct Target of MicroRNA-34a and Modulates the Proliferation and Migration of Retinal Pigment Epithelial ARPE-19 CellsGenome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levelsGene-based rare allele analysis identified a risk gene of Alzheimer's diseaseGenomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolateRare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancerDissecting the genetics of complex traits using summary association statisticsUsing GWAS to identify novel therapeutic targets for osteoporosis.Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.Mutations in eIF4ENIF1 are associated with primary ovarian insufficiency.Wnt-responsive cancer stem cells are located close to distorted blood vessels and not in hypoxic regions in a p53-null mouse model of human breast cancer.Efficient Bayesian mixed-model analysis increases association power in large cohorts.The impact of rare and low-frequency genetic variants in common diseaseLocal control of intestinal stem cell homeostasis by enteroendocrine cells in the adult Drosophila midgutPhenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment.Genome-wide Association Studies for Osteoporosis: A 2013 Update.Genomic variability in Mexican chicken population using copy number variants.The association between the baseline bone resorption marker CTX and incident dysglycemia after 4 yearsDistribution and medical impact of loss-of-function variants in the Finnish founder population.Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins.The revolution in human monogenic disease mapping.Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma.Analysis of LGR4 receptor distribution in human and mouse tissuesTargeted deletion of the murine Lgr4 gene decreases lens epithelial cell resistance to oxidative stress and induces age-related cataract formation.A Splice Region Variant in LDLR Lowers Non-high Density Lipoprotein Cholesterol and Protects against Coronary Artery Disease.Common and rare variants associated with kidney stones and biochemical traits.A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma.Interactions within the MHC contribute to the genetic architecture of celiac diseaseTwo-Variance-Component Model Improves Genetic Prediction in Family Datasets.Bivariate Genome-Wide Association Study Implicates ATP6V1G1 as a Novel Pleiotropic Locus Underlying Osteoporosis and Age at MenarcheSequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures.A Common Variant in CLDN14 is Associated with Primary Biliary Cirrhosis and Bone Mineral DensityCommon and rare variants associating with serum levels of creatine kinase and lactate dehydrogenase.A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.Identification of Common Genetic Variants Influencing Spontaneous Dizygotic Twinning and Female Fertility.The Tohoku Medical Megabank Project: Design and Mission.Pubertal timing and bone phenotype in early old age: findings from a British birth cohort study.HLA class II sequence variants influence tuberculosis risk in populations of European ancestry.Epigenetic and genetic components of height regulation.
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Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
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2013年學術文章
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name
Nonsense mutation in the LGR4 ...... man diseases and other traits.
@en
Nonsense mutation in the LGR4 ...... man diseases and other traits.
@nl
type
label
Nonsense mutation in the LGR4 ...... man diseases and other traits.
@en
Nonsense mutation in the LGR4 ...... man diseases and other traits.
@nl
prefLabel
Nonsense mutation in the LGR4 ...... man diseases and other traits.
@en
Nonsense mutation in the LGR4 ...... man diseases and other traits.
@nl
P2093
P2860
P50
P356
P1433
P1476
Nonsense mutation in the LGR4 ...... man diseases and other traits.
@en
P2093
Adalbjorg Jonasdottir
Agnar Helgason
Asgeir Sigurdsson
Asgeir Theodors
Aslaug Jonasdottir
Claus Christiansen
Erikur Steingrimsson
G Bragi Walters
Gisli Masson
Gudmundur I Eyjolfsson
P2860
P2888
P304
P356
10.1038/NATURE12124
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P50
P577
2013-05-05T00:00:00Z
P5875
P6179
1032844135