Opioid ligands with mixed properties from substituted enantiomeric N-phenethyl-5-phenylmorphans. Synthesis of a micro-agonist delta-antagonist and delta-inverse agonists.
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Probes for narcotic receptor mediated phenomena. 41. Unusual inverse μ-agonists and potent μ-opioid antagonists by modification of the N-substituent in enantiomeric 5-(3-hydroxyphenyl)morphansDiastereoselective one-pot synthesis of 7- and 8-substituted 5-phenylmorphans.Probes for narcotic receptor mediated phenomena. 37. Synthesis and opioid binding affinity of the final pair of oxide-bridged phenylmorphans, the ortho- and para-b-isomers and their N-phenethyl analogues, and the synthesis of the N-phenethyl analoguTranslation of structure-activity relationships from cyclic mixed efficacy opioid peptides to linear analoguesModulation of opioid receptor ligand affinity and efficacy using active and inactive state receptor models.Pentapeptides displaying mu opioid receptor agonist and delta opioid receptor partial agonist/antagonist propertiesModulation of opioid receptor affinity and efficacy via N-substitution of 9β-hydroxy-5-(3-hydroxyphenyl)morphan: Synthesis and computer simulation study.
P2860
Q34618176-31E37B2E-6334-4C29-8C5A-50832D67401FQ35958329-3139286C-B7D8-47B9-A9D8-5E967EFF4FDFQ37020421-16908F9D-A149-4140-996A-F9E8660BE25AQ39033568-0AA04173-0F1A-4D52-85A3-ADD37145B4D4Q39299621-0F014DF2-5453-4403-9812-4C608BB4BF63Q39793785-AE5902EF-110F-45FF-88C5-7EBC061A843FQ44344079-200214F5-0CA1-46D6-9ED9-989EF1AF401D
P2860
Opioid ligands with mixed properties from substituted enantiomeric N-phenethyl-5-phenylmorphans. Synthesis of a micro-agonist delta-antagonist and delta-inverse agonists.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Opioid ligands with mixed prop ...... st and delta-inverse agonists.
@en
Opioid ligands with mixed prop ...... st and delta-inverse agonists.
@nl
type
label
Opioid ligands with mixed prop ...... st and delta-inverse agonists.
@en
Opioid ligands with mixed prop ...... st and delta-inverse agonists.
@nl
prefLabel
Opioid ligands with mixed prop ...... st and delta-inverse agonists.
@en
Opioid ligands with mixed prop ...... st and delta-inverse agonists.
@nl
P2093
P2860
P356
P1476
Opioid ligands with mixed prop ...... st and delta-inverse agonists.
@en
P2093
Andrew Coop
Arthur E Jacobson
Christina M Dersch
Everette L May
In Jong Kim
Kejun Cheng
Kenner C Rice
Louis S Harris
Mario D Aceto
Mei-Jing Lee
P2860
P304
P356
10.1039/B618875C
P577
2007-03-01T00:00:00Z