Effect of the KCNQ potassium channel opener retigabine on single KCNQ2/3 channels expressed in CHO cells.
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Neural KCNQ (Kv7) channelsNew molecular targets for antiepileptic drugs: alpha(2)delta, SV2A, and K(v)7/KCNQ/M potassium channelsDiverse mechanisms of antiepileptic drugs in the development pipelineInactivation as a new regulatory mechanism for neuronal Kv7 channelsMechanisms of Action of Antiseizure Drugs and the Ketogenic DietThe acrylamide (S)-2 as a positive and negative modulator of Kv7 channels expressed in Xenopus laevis oocytesDual phosphorylations underlie modulation of unitary KCNQ K(+) channels by Src tyrosine kinaseThe KCNQ5 potassium channel mediates a component of the afterhyperpolarization current in mouse hippocampus.Hippocalcin and KCNQ channels contribute to the kinetics of the slow afterhyperpolarization.Combinatorial augmentation of voltage-gated KCNQ potassium channels by chemical openers.Contribution of near-threshold currents to intrinsic oscillatory activity in rat medial entorhinal cortex layer II stellate cells.The Sensorless Pore Module of Voltage-gated K+ Channel Family 7 Embodies the Target Site for the Anticonvulsant Retigabine.What determines the kinetics of the slow afterhyperpolarization (sAHP) in neurons?NGF inhibits M/KCNQ currents and selectively alters neuronal excitability in subsets of sympathetic neurons depending on their M/KCNQ current background.The Voltage Activation of Cortical KCNQ Channels Depends on Global PIP2 Levels.KCNQ channel openers reverse depressive symptoms via an active resilience mechanism.Kv7 channels: interaction with dopaminergic and serotonergic neurotransmission in the CNS.Potassium channels in peripheral pain pathways: expression, function and therapeutic potential.PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance.New and investigational antiepileptic drugs.Novel medications for epilepsy.The mechanism of action of retigabine (ezogabine), a first-in-class K+ channel opener for the treatment of epilepsy.Pharmacotherapy of the third-generation AEDs: lacosamide, retigabine and eslicarbazepine acetate.M-type K(+) channels in peripheral nociceptive pathways.Mechanisms underlying modulation of neuronal KCNQ2/KCNQ3 potassium channels by extracellular protonsActivation of peripheral KCNQ channels attenuates inflammatory pain.Thalamic Kv 7 channels: pharmacological properties and activity control during noxious signal processing.Retigabine: bending potassium channels to our will.Enhancing m currents: a way out for neuropathic pain?Activation of M1 muscarinic receptors triggers transmitter release from rat sympathetic neurons through an inhibition of M-type K+ channels.M channel enhancers and physiological M channel block.PIP2 mediates functional coupling and pharmacology of neuronal KCNQ channels.KCNQ/Kv7 channel regulation of hippocampal gamma-frequency firing in the absence of synaptic transmission.Pre- and postsynaptic activation of M-channels by a novel opener dampens neuronal firing and transmitter release.Angiotensin II regulates neuronal excitability via phosphatidylinositol 4,5-bisphosphate-dependent modulation of Kv7 (M-type) K+ channels.Ancient and modern anticonvulsants act synergistically in a KCNQ potassium channel binding pocket
P2860
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P2860
Effect of the KCNQ potassium channel opener retigabine on single KCNQ2/3 channels expressed in CHO cells.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Effect of the KCNQ potassium c ...... annels expressed in CHO cells.
@en
Effect of the KCNQ potassium c ...... annels expressed in CHO cells.
@nl
type
label
Effect of the KCNQ potassium c ...... annels expressed in CHO cells.
@en
Effect of the KCNQ potassium c ...... annels expressed in CHO cells.
@nl
prefLabel
Effect of the KCNQ potassium c ...... annels expressed in CHO cells.
@en
Effect of the KCNQ potassium c ...... annels expressed in CHO cells.
@nl
P2860
P1476
Effect of the KCNQ potassium c ...... annels expressed in CHO cells.
@en
P2093
P2860
P356
10.1113/JPHYSIOL.2003.039842
P407
P577
2003-04-17T00:00:00Z