Random mutagenesis of the M3 muscarinic acetylcholine receptor expressed in yeast. Identification of point mutations that "silence" a constitutively active mutant M3 receptor and greatly impair receptor/G protein coupling.
about
Cell adhesion receptor GPR133 couples to Gs proteinSignaling of the Human P2Y(1) Receptor Measured by a Yeast Growth Assay with Comparisons to Assays of Phospholipase C and Calcium Mobilization in 1321N1 Human Astrocytoma CellsRandom mutagenesis of the M3 muscarinic acetylcholine receptor expressed in yeast: identification of second-site mutations that restore function to a coupling-deficient mutant M3 receptor.The use of G-protein coupled receptor models in lead optimization.Beneficial metabolic effects caused by persistent activation of beta-cell M3 muscarinic acetylcholine receptors in transgenic mice.Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste.Novel insights into the function of β-cell M3 muscarinic acetylcholine receptors: therapeutic implications.Overexpression of membrane proteins from higher eukaryotes in yeasts.Influence of the accessory protein SET on M3 muscarinic receptor phosphorylation and G protein coupling.Constitutive activity of muscarinic acetylcholine receptors.Critical metabolic roles of β-cell M3 muscarinic acetylcholine receptorsMicrobial biosensors: engineered microorganisms as the sensing machineryThe proto-oncogene SET interacts with muscarinic receptors and attenuates receptor signaling.Minireview: Novel aspects of M3 muscarinic receptor signaling in pancreatic β-cells.Identification of an Ascaris G protein-coupled acetylcholine receptor with atypical muscarinic pharmacologyDetermination of adenosine A1 receptor agonist and antagonist pharmacology using Saccharomyces cerevisiae: implications for ligand screening and functional selectivity.A structural chemogenomics analysis of aminergic GPCRs: lessons for histamine receptor ligand design.Functional rescue of beta-adrenoceptor dimerization and trafficking by pharmacological chaperones.Muscarinic drugs regulate the PKG-II-dependent phosphorylation of M3 muscarinic acetylcholine receptors at plasma membranes from airway smooth muscle.Pronounced conformational changes following agonist activation of the M(3) muscarinic acetylcholine receptor.
P2860
Q24294618-5EFD6BCE-B56E-4072-8EF6-E0DEE99117CCQ25255546-D924054B-5B24-4246-9AED-F1C6CF3DF40BQ31133166-C5BF349A-3D68-4FA6-995E-1762031192B3Q33893103-47BA47D1-519E-4D2C-9A33-33394E808848Q34197823-080B70A5-04C0-4C7B-930B-52811FD61739Q34387670-8F379372-E450-4C65-874A-A03B048FB0B5Q34625376-417E9339-C5DF-44B1-8F6C-272AC916F38DQ35214601-EF2CCF74-6A17-4CA6-B489-E5A302B0BE13Q36057378-802EBFA0-FBC8-4007-A728-410E73E62AA7Q36440733-0939473A-8AAD-4C95-BF0A-104C8C374608Q36599383-E8F16E96-DFC3-4FB8-A596-45A11DE2BB2EQ36947952-32BB159D-258E-48B9-83F6-6F418BA95CA8Q37001177-43565744-749E-4C07-9F73-6731CBB80735Q37050369-CDCCA906-2D83-493E-9F4D-528080623D7EQ37268692-E47A1C17-8A5F-4C1A-988E-098E7EF84C4CQ37397259-35364FF7-26B3-4425-991F-8CDFAEB4482CQ39411714-E80AD425-75C5-498B-8C97-0AB2BFDD493AQ39839857-DBB918AC-2358-4D78-8785-114FCA5B8882Q42478037-3B8E04DD-0A52-4422-9590-07CBFCE70081Q46471179-E8576FB4-49B5-4417-BBD3-201D3E56B41E
P2860
Random mutagenesis of the M3 muscarinic acetylcholine receptor expressed in yeast. Identification of point mutations that "silence" a constitutively active mutant M3 receptor and greatly impair receptor/G protein coupling.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Random mutagenesis of the M3 m ...... r receptor/G protein coupling.
@en
Random mutagenesis of the M3 m ...... r receptor/G protein coupling.
@nl
type
label
Random mutagenesis of the M3 m ...... r receptor/G protein coupling.
@en
Random mutagenesis of the M3 m ...... r receptor/G protein coupling.
@nl
prefLabel
Random mutagenesis of the M3 m ...... r receptor/G protein coupling.
@en
Random mutagenesis of the M3 m ...... r receptor/G protein coupling.
@nl
P2093
P2860
P356
P1476
Random mutagenesis of the M3 m ...... r receptor/G protein coupling.
@en
P2093
Clarice Schmidt
Fu-Yue Zeng
Isolde Erlenbach
Jürgen Wess
Lanh Bloodworth
P2860
P304
30248-30260
P356
10.1074/JBC.M304991200
P407
P577
2003-05-15T00:00:00Z