Selective induction of dendritic cells using granulocyte macrophage-colony stimulating factor, but not fms-like tyrosine kinase receptor 3-ligand, activates thyroglobulin-specific CD4+/CD25+ T cells and suppresses experimental autoimmune thyroiditis
about
GM-CSF: An immune modulatory cytokine that can suppress autoimmunityNeuroantigen-specific, tolerogenic vaccines: GM-CSF is a fusion partner that facilitates tolerance rather than immunity to dominant self-epitopes of myelin in murine models of experimental autoimmune encephalomyelitis (EAE).Cure of established GL261 mouse gliomas after combined immunotherapy with GM-CSF and IFNgamma is mediated by both CD8+ and CD4+ T-cells.Endogenous CD4+ CD25+ regulatory T cells play no apparent role in the acute humoral response to intact Streptococcus pneumoniae.Dendritic cell-directed CTLA-4 engagement during pancreatic beta cell antigen presentation delays type 1 diabetes.Cellular therapies supplement: the role of granulocyte macrophage colony-stimulating factor and dendritic cells in regulatory T-cell homeostasis and expansion.GM-CSF-neuroantigen fusion proteins reverse experimental autoimmune encephalomyelitis and mediate tolerogenic activity in adjuvant-primed environments: association with inflammation-dependent, inhibitory antigen presentation.Adaptive immune regulation of glial homeostasis as an immunization strategy for neurodegenerative diseasesGM-CSF-induced, bone-marrow-derived dendritic cells can expand natural Tregs and induce adaptive Tregs by different mechanisms.Natural regulatory T cells in autoimmunity.Role of cytokines in the pathogenesis and suppression of thyroid autoimmunity.GM-CSF-induced regulatory T cells selectively inhibit anti-acetylcholine receptor-specific immune responses in experimental myasthenia gravisModulation of dendritic cell function and cytokine production to prevent thyroid autoimmunity.A role for granulocyte-macrophage colony-stimulating factor in the regulation of CD8(+) T cell responses to rabies virus.Dual Role of GM-CSF as a Pro-Inflammatory and a Regulatory Cytokine: Implications for Immune Therapy.Cytokine-neuroantigen fusion proteins as a new class of tolerogenic, therapeutic vaccines for treatment of inflammatory demyelinating disease in rodent models of multiple sclerosisTolerance induction by viral in vivo gene transferThymic stromal lymphopoietin and thymic stromal lymphopoietin-conditioned dendritic cells induce regulatory T-cell differentiation and protection of NOD mice against diabetesRegulatory T cells induced by GM-CSF suppress ongoing experimental myasthenia gravisStrategies for treating autoimmunity: novel insights from experimental myasthenia gravisGM-CSF-induced CD11c+CD8a--dendritic cells facilitate Foxp3+ and IL-10+ regulatory T cell expansion resulting in suppression of autoimmune thyroiditisTumor necrosis factor-related apoptosis-inducing ligand inhibits experimental autoimmune thyroiditis by the expansion of CD4+CD25+ regulatory T cells.CD11c+CD11b+ dendritic cells play an important role in intravenous tolerance and the suppression of experimental autoimmune encephalomyelitisImmune modulation by melanoma-derived factors.Modulation of dendritic cells using granulocyte-macrophage colony-stimulating factor (GM-CSF) delays type 1 diabetes by enhancing CD4+CD25+ regulatory T cell functionInnate and adaptive immunity for the pathobiology of Parkinson's diseaseSoluble OX40L and JAG1 Induce Selective Proliferation of Functional Regulatory T-Cells Independent of canonical TCR signalingThe role of ancestim (recombinant human stem-cell factor, rhSCF) in hematopoietic stem cell mobilization and hematopoietic reconstitution.Novel agents and approaches for stem cell mobilization in normal donors and patients.Mechanisms of antitumor and immune-enhancing activities of MUC1/sec, a secreted form of mucin-1.Murine and Human Model Systems for the Study of Dendritic Cell Immunobiology.OX40L/Jagged1 cosignaling by GM-CSF-induced bone marrow-derived dendritic cells is required for the expansion of functional regulatory T cells.PKC-ѳ is dispensable for OX40L-induced TCR-independent Treg proliferation but contributes by enabling IL-2 production from effector T-cells.Age-dependent divergent effects of OX40L treatment on the development of diabetes in NOD mice.Depletion of CD4+ CD25+ regulatory T cells confers susceptibility to experimental autoimmune encephalomyelitis (EAE) in GM-CSF-deficient Csf2-/- mice.GM-CSF and IL-4 synergistically trigger dendritic cells to acquire retinoic acid-producing capacity.Systemic GM-CSF Recruits Effector T Cells into the Tumor Microenvironment in Localized Prostate Cancer.Tolerogenic bone marrow-derived dendritic cells induce neuroprotective regulatory T cells in a model of Parkinson's disease.Identification of a Novel OX40L Dendritic Cell Subset That Selectively Expands Regulatory T cellsReduced risk of acute GVHD following mobilization of HLA-identical sibling donors with GM-CSF alone
P2860
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P2860
Selective induction of dendritic cells using granulocyte macrophage-colony stimulating factor, but not fms-like tyrosine kinase receptor 3-ligand, activates thyroglobulin-specific CD4+/CD25+ T cells and suppresses experimental autoimmune thyroiditis
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Selective induction of dendrit ...... imental autoimmune thyroiditis
@en
Selective induction of dendrit ...... imental autoimmune thyroiditis
@nl
type
label
Selective induction of dendrit ...... imental autoimmune thyroiditis
@en
Selective induction of dendrit ...... imental autoimmune thyroiditis
@nl
prefLabel
Selective induction of dendrit ...... imental autoimmune thyroiditis
@en
Selective induction of dendrit ...... imental autoimmune thyroiditis
@nl
P2093
P1476
Selective induction of dendrit ...... imental autoimmune thyroiditis
@en
P2093
Bellur S Prabhakar
Mark J Holterman
Rukiye-Nazan E Dogan
P304
P356
10.4049/JIMMUNOL.170.11.5511
P407
P577
2003-06-01T00:00:00Z