Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos.
about
Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5Relief of profound feedback inhibition of mitogenic signaling by RAF inhibitors attenuates their activity in BRAFV600E melanomasThe RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cellsExtracellular signal-regulated kinases phosphorylate mitogen-activated protein kinase phosphatase 3/DUSP6 at serines 159 and 197, two sites critical for its proteasomal degradationThe regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs)MEK inhibitors and their potential in the treatment of advanced melanoma: the advantages of combination therapyThe fin-to-limb transition as the re-organization of a Turing patternCellular signaling by fibroblast growth factors (FGFs) and their receptors (FGFRs) in male reproduction.Generation of FGF reporter transgenic zebrafish and their utility in chemical screens.A distinct role for secreted fibroblast growth factor-binding proteins in development.FGF signaling controls caudal hindbrain specification through Ras-ERK1/2 pathway.Enhanced inhibition of ERK signaling by a novel allosteric MEK inhibitor, CH5126766, that suppresses feedback reactivation of RAF activity.The dual-specificity protein phosphatase DUSP9/MKP-4 is essential for placental function but is not required for normal embryonic developmentMajor transcriptome re-organisation and abrupt changes in signalling, cell cycle and chromatin regulation at neural differentiation in vivo.The Fibroblast Growth Factor signaling pathwayGeneration and characterization of a novel mouse embryonic stem cell line with a dynamic reporter of Nanog expression.HMGB factors are required for posterior digit development through integrating signaling pathway activitiesSprouty2 mediated tuning of signalling is essential for somite myogenesis.Exogenous fibroblast growth factor-10 induces cystic lung development with altered target gene expression in the presence of heparin in cultures of embryonic rat lung.Ubiquitin pathway and ovarian cancer.Role of Epiprofin, a zinc-finger transcription factor, in limb development.Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development.Genetic complementation screen identifies a mitogen-activated protein kinase phosphatase, MKP3, as a regulator of dopamine transporter traffickingInhibition of mitogen-activated protein kinase phosphatase 3 activity by interdomain bindingThe dual-specificity MAP kinase phosphatases: critical roles in development and cancer.Post-transcriptional regulation of the Ras-ERK/MAPK signaling pathway.Specification and regionalisation of the neural plate border.Pleiotropic functions of fibroblast growth factor signaling in embryonic mammary gland development.Receptor tyrosine kinase (RTK) signalling in the control of neural stem and progenitor cell (NSPC) development.A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts.DUSP6 regulates drug sensitivity by modulating DNA damage response.Molecular Pathways: Maintaining MAPK Inhibitor Sensitivity by Targeting Nonmutational Tolerance.Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter.Follicle-Stimulating Hormone (FSH)-dependent Regulation of Extracellular Regulated Kinase (ERK) Phosphorylation by the Mitogen-activated Protein (MAP) Kinase Phosphatase MKP3.Induction of MAP kinase phosphatase 3 through Erk/MAP kinase activation in three oncogenic Ras (H-, K- and N-Ras)-expressing NIH/3T3 mouse embryonic fibroblast cell lines.Wnt and FGF signals interact to coordinate growth with cell fate specification during limb developmentDUSP6, a tumor suppressor, is involved in differentiation and apoptosis in esophageal squamous cell carcinomaCompensatory regulation of the size of the inner ear in response to excess induction of otic progenitors by fibroblast growth factor signalingThe emergence of ectomesenchymeA SHH-responsive signaling center in the forebrain regulates craniofacial morphogenesis via the facial ectoderm.
P2860
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P2860
Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos.
@en
Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos.
@nl
type
label
Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos.
@en
Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos.
@nl
prefLabel
Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos.
@en
Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos.
@nl
P2093
P50
P1433
P1476
Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos
@en
P2093
Elizabeth R Farrell
J Simon Lunn
Joanne Mathers
Maxwell C Eblaghie
Robin J Dickinson
P304
P356
10.1016/S0960-9822(03)00381-6
P407
P577
2003-06-01T00:00:00Z