Protein phosphatase 2A-linked and -unlinked caspase-dependent pathways for downregulation of Akt kinase triggered by 4-hydroxynonenal. - Wikidata - wikimedia - TriplyDB

Protein phosphatase 2A-linked and -unlinked caspase-dependent pathways for downregulation of Akt kinase triggered by 4-hydroxynonenal.

Protein phosphatase 2A-linked and -unlinked caspase-dependent pathways for downregulation of Akt kinase triggered by 4-hydroxynonenal.

http://www.wikidata.org/entity/Q44483591

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Phosphoprotein phosphatase 2A: a novel druggable target for Alzheimer's disease BIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cells Src kinase up-regulates the ERK cascade through inactivation of protein phosphatase 2A following cerebral ischemia.Physiological regulation of Akt activity and stability.Identification of 5' AMP-activated kinase as a target of reactive aldehydes during chronic ingestion of high concentrations of ethanol.3,3'-Diindolylmethane exhibits antileukemic activity in vitro and in vivo through a Akt-dependent process.Ceramide-activated phosphatase mediates fatty acid-induced endothelial VEGF resistance and impaired angiogenesis Stereoselective effects of 4-hydroxynonenal in cultured mouse hepatocytes.DNA damage signaling guards against perturbation of cyclin D1 expression triggered by low-dose long-term fractionated radiation Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibition by 4-hydroxynonenal leads to increased Akt activation in hepatocytes.Cigarette smoke induces Akt protein degradation by the ubiquitin-proteasome system 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells Aldehyde dehydrogenase-2 deficiency aggravates cardiac dysfunction elicited by endoplasmic reticulum stress induction.Constitutively activated CK2 potentially plays a pivotal role in Theileria-induced lymphocyte transformation.Resistin, a fat-derived secretory factor, promotes metastasis of MDA-MB-231 human breast cancer cells through ERM activation.Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia.Oxidative stress contributes to the tamoxifen-induced killing of breast cancer cells: implications for tamoxifen therapy and resistance.Role of 4-hydroxynonenal and its metabolites in signaling.Mitochondrial reactive oxygen species perturb AKT/cyclin D1 cell cycle signaling via oxidative inactivation of PP2A in lowdose irradiated human fibroblasts.Mitochondrial reactive oxygen species-mediated genomic instability in low-dose irradiated human cells through nuclear retention of cyclin D1.Self-regulatory role of 4-hydroxynonenal in signaling for stress-induced programmed cell death.Novel Ser/Thr protein phosphatases in cell death regulation Acrolein, a ubiquitous pollutant and lipid hydroperoxide product, inhibits antiviral activity of interferon-alpha: relevance to hepatitis C.Protein Phosphatase 1-α Regulates AS160 Ser588 and Thr642 Dephosphorylation in Skeletal Muscle.4-Hydroxynonenal activates Src through a non-canonical pathway that involves EGFR/PTP1B.4-hydroxynonenal-mediated signaling and aging.Lipid rafts couple store-operated Ca2+ entry to constitutive activation of PKB/Akt in a Ca2+/calmodulin-, Src- and PP2A-mediated pathway and promote melanoma tumor growth.A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes.Novel 2'-substituted, 3'-deoxy-phosphatidyl-myo-inositol analogues reduce drug resistance in human leukaemia cell lines with an activated phosphoinositide 3-kinase/Akt pathway.Antiapoptotic activity of Akt is down-regulated by Ca2+ in myocardiac H9c2 cells. Evidence of Ca(2+)-dependent regulation of protein phosphatase 2Ac.4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase Aldehyde dehydrogenase 2 (ALDH2) rescues myocardial ischaemia/reperfusion injury: role of autophagy paradox and toxic aldehyde.GADD45β mediates p53 protein degradation via Src/PP2A/MDM2 pathway upon arsenite treatment.Activation of adenovirus type 2 early region 4 ORF4 cytoplasmic death function by direct binding to Src kinase domain.Hyperosmotic stress contributes to mouse colonic inflammation through the methylation of protein phosphatase 2A.PP2A mediates apoptosis or autophagic cell death in multiple myeloma cell lines.Caspase-3 inhibition prevents the development of hepatopulmonary syndrome in common bile duct ligation rats by alleviating pulmonary injury.A pro-survival effect of polyamine depletion on norepinephrine-mediated apoptosis in cardiac cells: role of signaling enzymes.

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Protein phosphatase 2A-linked and -unlinked caspase-dependent pathways for downregulation of Akt kinase triggered by 4-hydroxynonenal.

http://www.wikidata.org/entity/Q44483591

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2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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2003年學術文章

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name

Protein phosphatase 2A-linked ...... triggered by 4-hydroxynonenal.

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Protein phosphatase 2A-linked ...... triggered by 4-hydroxynonenal.

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type

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Protein phosphatase 2A-linked ...... triggered by 4-hydroxynonenal.

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Protein phosphatase 2A-linked ...... triggered by 4-hydroxynonenal.

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Protein phosphatase 2A-linked ...... triggered by 4-hydroxynonenal.

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Protein phosphatase 2A-linked ...... triggered by 4-hydroxynonenal.

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Protein phosphatase 2A-linked ...... triggered by 4-hydroxynonenal.

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A A Akhand

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H Suzuki

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I Nakashima

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K Takeda

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M Itoigawa

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W Liu

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Y Kawamoto

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P2860

The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

Direct control of the Forkhead transcription factor AFX by protein kinase B

Purification of porcine brain protein phosphatase 2A leucine carboxyl methyltransferase and cloning of the human homologue

Integrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta.

Carboxyl methylation regulates phosphoprotein phosphatase 2A by controlling the association of regulatory B subunits

Carboxyl methylation of the phosphoprotein phosphatase 2A catalytic subunit promotes its functional association with regulatory subunits in vivo

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta

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