Protein phosphatase 2A-linked and -unlinked caspase-dependent pathways for downregulation of Akt kinase triggered by 4-hydroxynonenal.
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Phosphoprotein phosphatase 2A: a novel druggable target for Alzheimer's diseaseBIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cellsSrc kinase up-regulates the ERK cascade through inactivation of protein phosphatase 2A following cerebral ischemia.Physiological regulation of Akt activity and stability.Identification of 5' AMP-activated kinase as a target of reactive aldehydes during chronic ingestion of high concentrations of ethanol.3,3'-Diindolylmethane exhibits antileukemic activity in vitro and in vivo through a Akt-dependent process.Ceramide-activated phosphatase mediates fatty acid-induced endothelial VEGF resistance and impaired angiogenesisStereoselective effects of 4-hydroxynonenal in cultured mouse hepatocytes.DNA damage signaling guards against perturbation of cyclin D1 expression triggered by low-dose long-term fractionated radiationPhosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibition by 4-hydroxynonenal leads to increased Akt activation in hepatocytes.Cigarette smoke induces Akt protein degradation by the ubiquitin-proteasome system8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cellsAldehyde dehydrogenase-2 deficiency aggravates cardiac dysfunction elicited by endoplasmic reticulum stress induction.Constitutively activated CK2 potentially plays a pivotal role in Theileria-induced lymphocyte transformation.Resistin, a fat-derived secretory factor, promotes metastasis of MDA-MB-231 human breast cancer cells through ERM activation.Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia.Oxidative stress contributes to the tamoxifen-induced killing of breast cancer cells: implications for tamoxifen therapy and resistance.Role of 4-hydroxynonenal and its metabolites in signaling.Mitochondrial reactive oxygen species perturb AKT/cyclin D1 cell cycle signaling via oxidative inactivation of PP2A in lowdose irradiated human fibroblasts.Mitochondrial reactive oxygen species-mediated genomic instability in low-dose irradiated human cells through nuclear retention of cyclin D1.Self-regulatory role of 4-hydroxynonenal in signaling for stress-induced programmed cell death.Novel Ser/Thr protein phosphatases in cell death regulationAcrolein, a ubiquitous pollutant and lipid hydroperoxide product, inhibits antiviral activity of interferon-alpha: relevance to hepatitis C.Protein Phosphatase 1-α Regulates AS160 Ser588 and Thr642 Dephosphorylation in Skeletal Muscle.4-Hydroxynonenal activates Src through a non-canonical pathway that involves EGFR/PTP1B.4-hydroxynonenal-mediated signaling and aging.Lipid rafts couple store-operated Ca2+ entry to constitutive activation of PKB/Akt in a Ca2+/calmodulin-, Src- and PP2A-mediated pathway and promote melanoma tumor growth.A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulationHistone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes.Novel 2'-substituted, 3'-deoxy-phosphatidyl-myo-inositol analogues reduce drug resistance in human leukaemia cell lines with an activated phosphoinositide 3-kinase/Akt pathway.Antiapoptotic activity of Akt is down-regulated by Ca2+ in myocardiac H9c2 cells. Evidence of Ca(2+)-dependent regulation of protein phosphatase 2Ac.4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferaseAldehyde dehydrogenase 2 (ALDH2) rescues myocardial ischaemia/reperfusion injury: role of autophagy paradox and toxic aldehyde.GADD45β mediates p53 protein degradation via Src/PP2A/MDM2 pathway upon arsenite treatment.Activation of adenovirus type 2 early region 4 ORF4 cytoplasmic death function by direct binding to Src kinase domain.Hyperosmotic stress contributes to mouse colonic inflammation through the methylation of protein phosphatase 2A.PP2A mediates apoptosis or autophagic cell death in multiple myeloma cell lines.Caspase-3 inhibition prevents the development of hepatopulmonary syndrome in common bile duct ligation rats by alleviating pulmonary injury.A pro-survival effect of polyamine depletion on norepinephrine-mediated apoptosis in cardiac cells: role of signaling enzymes.
P2860
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P2860
Protein phosphatase 2A-linked and -unlinked caspase-dependent pathways for downregulation of Akt kinase triggered by 4-hydroxynonenal.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Protein phosphatase 2A-linked ...... triggered by 4-hydroxynonenal.
@en
Protein phosphatase 2A-linked ...... triggered by 4-hydroxynonenal.
@nl
type
label
Protein phosphatase 2A-linked ...... triggered by 4-hydroxynonenal.
@en
Protein phosphatase 2A-linked ...... triggered by 4-hydroxynonenal.
@nl
prefLabel
Protein phosphatase 2A-linked ...... triggered by 4-hydroxynonenal.
@en
Protein phosphatase 2A-linked ...... triggered by 4-hydroxynonenal.
@nl
P2093
P2860
P356
P1476
Protein phosphatase 2A-linked ...... triggered by 4-hydroxynonenal.
@en
P2093
A A Akhand
I Nakashima
M Itoigawa
N Ishikawa
Y Kawamoto
P2860
P2888
P304
P356
10.1038/SJ.CDD.4401238
P577
2003-07-01T00:00:00Z