Beta-amyloid regulation of presynaptic nicotinic receptors in rat hippocampus and neocortex.
about
Allosteric modulator Desformylflustrabromine relieves the inhibition of α2β2 and α4β2 nicotinic acetylcholine receptors by β-amyloid(1-42) peptideThe toxicity of amyloid β oligomersMammalian nicotinic acetylcholine receptors: from structure to functionNicotinic ACh receptors in the hippocampal circuit; functional expression and role in synaptic plasticityNicotinic ACh receptors as therapeutic targets in CNS disordersAmyloid-β acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2Mossy fiber long-term potentiation deficits in BACE1 knock-outs can be rescued by activation of alpha7 nicotinic acetylcholine receptorsPicomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus.Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease.Amyloid oligomer neurotoxicity, calcium dysregulation, and lipid raftsCortical alpha7 nicotinic acetylcholine receptor and beta-amyloid levels in early Alzheimer disease.Positron emission tomography imaging and clinical progression in relation to molecular pathology in the first Pittsburgh Compound B positron emission tomography patient with Alzheimer's diseaseDeleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection.A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptidesAmyloid-beta-induced ion flux in artificial lipid bilayers and neuronal cells: resolving a controversyPicomolar amyloid-β peptides enhance spontaneous astrocyte calcium transientsEndogenous signaling through alpha7-containing nicotinic receptors promotes maturation and integration of adult-born neurons in the hippocampus.Dual effect of beta-amyloid on α7 and α4β2 nicotinic receptors controlling the release of glutamate, aspartate and GABA in rat hippocampus.Regulation of presynaptic Ca2+, synaptic plasticity and contextual fear conditioning by a N-terminal β-amyloid fragment.β-amyloid oligomers and prion protein: Fatal attraction?Amyloid-β as a modulator of synaptic plasticityRescue of amyloid-Beta-induced inhibition of nicotinic acetylcholine receptors by a peptide homologous to the nicotine binding domain of the alpha 7 subtype.α7 Nicotinic receptor-mediated astrocytic gliotransmitter release: Aβ effects in a preclinical Alzheimer's mouse model.Role of key aromatic residues in the ligand-binding domain of alpha7 nicotinic receptors in the agonist action of beta-amyloid.The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease.Subtype-specific actions of beta-amyloid peptides on recombinant human neuronal nicotinic acetylcholine receptors (alpha7, alpha4beta2, alpha3beta4) expressed in Xenopus laevis oocytes.Staying connected: synapses in Alzheimer disease.Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic miceThe keystone of Alzheimer pathogenesis might be sought in Aβ physiologyAnalyzing and Modeling the Dysfunction of Inhibitory Neurons in Alzheimer's Disease.Impact of sustained exposure to β-amyloid on calcium homeostasis and neuronal integrity in model nerve cell system expressing α4β2 nicotinic acetylcholine receptorsCholinergic receptors: functional role of nicotinic ACh receptors in brain circuits and disease.Neuronal calcium mishandling and the pathogenesis of Alzheimer's diseaseAmyloid-β peptide: Dr. Jekyll or Mr. Hyde?Long-lasting distortion of GABA signaling in MS/DB neurons after binge-like ethanol exposure during initial synaptogenesis.Inhibition of native and recombinant nicotinic acetylcholine receptors by the myristoylated alanine-rich C kinase substrate peptide.SUMO and Alzheimer's disease.The Role of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) in Cognition.Relationships between the amyloid precursor protein and its various proteolytic fragments and neuronal systems.
P2860
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P2860
Beta-amyloid regulation of presynaptic nicotinic receptors in rat hippocampus and neocortex.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Beta-amyloid regulation of pre ...... rat hippocampus and neocortex.
@en
Beta-amyloid regulation of pre ...... rat hippocampus and neocortex.
@nl
type
label
Beta-amyloid regulation of pre ...... rat hippocampus and neocortex.
@en
Beta-amyloid regulation of pre ...... rat hippocampus and neocortex.
@nl
prefLabel
Beta-amyloid regulation of pre ...... rat hippocampus and neocortex.
@en
Beta-amyloid regulation of pre ...... rat hippocampus and neocortex.
@nl
P2093
P1476
Beta-amyloid regulation of pre ...... rat hippocampus and neocortex
@en
P2093
Jianlin Wu
John J Dougherty
Robert A Nichols
P304
P356
10.1523/JNEUROSCI.23-17-06740.2003
P407
P577
2003-07-01T00:00:00Z