Ligand-independent activation of vascular endothelial growth factor receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase.
about
Unspliced X-box-binding protein 1 (XBP1) protects endothelial cells from oxidative stress through interaction with histone deacetylase 3Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesisAIP1 functions as an endogenous inhibitor of VEGFR2-mediated signaling and inflammatory angiogenesis in miceEarly VEGFR2 activation in response to flow is VEGF-dependent and mediated by MMP activityMolecular mechanisms of ghrelin-mediated endothelial nitric oxide synthase activationHigh shear stress induces atherosclerotic vulnerable plaque formation through angiogenesisMechanisms of neovascularization and resistance to anti-angiogenic therapies in glioblastoma multiformeStop the flow: a paradigm for cell signaling mediated by reactive oxygen species in the pulmonary endotheliumCanonical and noncanonical vascular endothelial growth factor pathways: new developments in biology and signal transduction.Venous congestion, endothelial and neurohormonal activation in acute decompensated heart failure: cause or effect?Etk/Bmx transactivates vascular endothelial growth factor 2 and recruits phosphatidylinositol 3-kinase to mediate the tumor necrosis factor-induced angiogenic pathwayPressure-induced maturation of endothelial cells on newborn mouse carotid arteriesInterference with the host haemostatic system by schistosomesFlow-dependent cellular mechanotransduction in atherosclerosis.Systems biology of vascular endothelial growth factorsMechanotransduction in vascular physiology and atherogenesis.Prediction of sphingosine 1-phosphate-stimulated endothelial cell migration rates using biochemical measurementsHIF-1alpha and HIF-2alpha play a central role in stretch-induced but not shear-stress-induced angiogenesis in rat skeletal muscle.A ligand-independent VEGFR2 signaling pathway limits angiogenic responses in diabetes.Opioids: Modulators of angiogenesis in wound healing and cancer.Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOSDecreased vascular lesion formation in mice with inducible endothelial-specific expression of protein kinase AktFlow shear stress stimulates Gab1 tyrosine phosphorylation to mediate protein kinase B and endothelial nitric-oxide synthase activation in endothelial cells.A novel role of vascular endothelial cadherin in modulating c-Src activation and downstream signaling of vascular endothelial growth factorProtein kinase C-dependent protein kinase D activation modulates ERK signal pathway and endothelial cell proliferation by vascular endothelial growth factorHistone deacetylase 5 interacts with Krüppel-like factor 2 and inhibits its transcriptional activity in endothelium.Acute mechanical stretch promotes eNOS activation in venous endothelial cells mainly via PKA and Akt pathways.The Krüppel-like factor 2 and Krüppel-like factor 4 genes interact to maintain endothelial integrity in mouse embryonic vasculogenesisIntramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex.Downstream exposure to growth factors causes elevated velocity and dilation in arteriolar networks.Coupling of Fcγ receptor I to Fcγ receptor IIb by SRC kinase mediates C-reactive protein impairment of endothelial function.Rap1 promotes endothelial mechanosensing complex formation, NO release and normal endothelial function.The Vital Role of Blood Flow-Induced Proliferation and Migration in Capillary Network Formation in a Multiscale Model of Angiogenesis.The relevance of cell type- and tumor zone-specific VEGFR-2 activation in locally advanced colon cancer.Fluid flows and forces in development: functions, features and biophysical principles.Role of reactive oxygen and nitrogen species in the vascular responses to inflammation.The role of shear stress in the pathogenesis of atherosclerosis.VEGF Receptor-2-Linked PI3K/Calpain/SIRT1 Activation Mediates Retinal Arteriolar Dilations to VEGF and Shear Stress.Passive heat therapy improves cutaneous microvascular function in sedentary humans via improved nitric oxide-dependent dilation.Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation.
P2860
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P2860
Ligand-independent activation of vascular endothelial growth factor receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Ligand-independent activation ...... thelial nitric oxide synthase.
@en
Ligand-independent activation ...... thelial nitric oxide synthase.
@nl
type
label
Ligand-independent activation ...... thelial nitric oxide synthase.
@en
Ligand-independent activation ...... thelial nitric oxide synthase.
@nl
prefLabel
Ligand-independent activation ...... thelial nitric oxide synthase.
@en
Ligand-independent activation ...... thelial nitric oxide synthase.
@nl
P2093
P1433
P1476
Ligand-independent activation ...... thelial nitric oxide synthase.
@en
P2093
Andreea O Lungu
Hiroto Ueba
Mary D Frame
Tatsuo Tanimoto
Zheng-Gen Jin
P304
P356
10.1161/01.RES.0000089257.94002.96
P577
2003-07-31T00:00:00Z