A novel role for FAK as a protease-targeting adaptor protein: regulation by p42 ERK and Src.
about
FAK promotes recruitment of talin to nascent adhesions to control cell motilityCAP interacts with cytoskeletal proteins and regulates adhesion-mediated ERK activation and motilityThe MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals.Paxillin comes of agePhosphorylation of actopaxin regulates cell spreading and migrationRACK1 targets the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway to link integrin engagement with focal adhesion disassembly and cell motilityCortactin as a target for FAK in the regulation of focal adhesion dynamicsMUC1 cytoplasmic tail: a potential therapeutic target for ovarian carcinomaFAK competes for Src to promote migration against invasion in melanoma cells.Rapid Discovery and Structure-Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL KinaseFAK and paxillin dynamics at focal adhesions in the protrusions of migrating cells.Integrins in cell migrationTyrosine phosphorylation of Rac1: a role in regulation of cell spreadingExtracellular signal-regulated kinase promotes Rho-dependent focal adhesion formation by suppressing p190A RhoGAP.Integrin signalling in directed cell migration.B-RAF regulation of Rnd3 participates in actin cytoskeletal and focal adhesion organizationSpatial localization of m-calpain to the plasma membrane by phosphoinositide biphosphate binding during epidermal growth factor receptor-mediated activationc-Src-mediated epithelial cell migration and invasion regulated by PDZ binding site.Membrane depolarization inhibits spiral ganglion neurite growth via activation of multiple types of voltage sensitive calcium channels and calpainRegulation of adhesion dynamics by calpain-mediated proteolysis of focal adhesion kinase (FAK).FAK phosphorylation at Tyr-925 regulates cross-talk between focal adhesion turnover and cell protrusion.Organization and post-transcriptional processing of focal adhesion kinase gene.Host-pathogen systems biology: logical modelling of hepatocyte growth factor and Helicobacter pylori induced c-Met signal transductionFocal adhesion kinase: a prominent determinant in breast cancer initiation, progression and metastasisDownregulation of Talin1 promotes hepatocellular carcinoma progression through activation of the ERK1/2 pathway.Trihydrophobin 1 phosphorylation by c-Src regulates MAPK/ERK signaling and cell migrationFilamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion.Calpain is required for normal osteoclast function and is down-regulated by calcitoninPrenylation inhibition-induced cell death in melanoma: reduced sensitivity in BRAF mutant/PTEN wild-type melanoma cellsFocal adhesions and Ras are functionally and spatially integrated to mediate IL-1 activation of ERK.Dasatinib-related chylothoraxA Potential Role for the Inhibition of PI3K Signaling in Glioblastoma Therapy.Transcriptional signature induced by a metastasis-promoting c-Src mutant in a human breast cell line.Protein kinase G and focal adhesion kinase converge on Src/Akt/β-catenin signaling module in osteoblast mechanotransductionIdentification of targets of c-Src tyrosine kinase by chemical complementation and phosphoproteomicsScaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective.ERK-ERF-EGR1, a novel switch underlying acquisition of a motile phenotype.Regulation of MAPKs by growth factors and receptor tyrosine kinasesSerine protease HtrA1 associates with microtubules and inhibits cell migration.Mechanotransduction at focal adhesions: integrating cytoskeletal mechanics in migrating cells.
P2860
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P2860
A novel role for FAK as a protease-targeting adaptor protein: regulation by p42 ERK and Src.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
A novel role for FAK as a prot ...... regulation by p42 ERK and Src.
@en
A novel role for FAK as a prot ...... regulation by p42 ERK and Src.
@nl
type
label
A novel role for FAK as a prot ...... regulation by p42 ERK and Src.
@en
A novel role for FAK as a prot ...... regulation by p42 ERK and Src.
@nl
prefLabel
A novel role for FAK as a prot ...... regulation by p42 ERK and Src.
@en
A novel role for FAK as a prot ...... regulation by p42 ERK and Src.
@nl
P2093
P1433
P1476
A novel role for FAK as a prot ...... regulation by p42 ERK and Src
@en
P2093
Margaret C Frame
Michael D Schaller
Valerie J Fincham
P304
P356
10.1016/S0960-9822(03)00544-X
P407
P577
2003-08-01T00:00:00Z