about
Killing me softly--future challenges in apoptosis researchPhosphoinositide 3-kinases upregulate system xc(-) via eukaryotic initiation factor 2α and activating transcription factor 4 - A pathway active in glioblastomas and epilepsySequential dosing in chemosensitization: targeting the PI3K/Akt/mTOR pathway in neuroblastoma.A Potential Role for the Inhibition of PI3K Signaling in Glioblastoma Therapy.Immune phenotypes predict survival in patients with glioblastoma multiforme.TIC10/ONC201 synergizes with Bcl-2/Bcl-xL inhibition in glioblastoma by suppression of Mcl-1 and its binding partners in vitro and in vivo.Inhibition of deubiquitinases primes glioblastoma cells to apoptosis in vitro and in vivo.Adhesion-mediated apoptosis resistance in cancer.Exogenous cathepsin G upregulates cell surface MHC class I molecules on immune and glioblastoma cells.Cerebral Microstructural Alterations after Radiation Therapy in High-Grade Glioma: A Diffusion Tensor Imaging-Based StudyCell Death Induction in Cancer Therapy - Past, Present, and Future.Cathepsin G-mediated proteolytic degradation of MHC class I molecules to facilitate immune detection of human glioblastoma cells.Simultaneous Interference with HER1/EGFR and RAC1 Signaling Drives Cytostasis and Suppression of Survivin in Human Glioma Cells in Vitro.Olanzapine inhibits proliferation, migration and anchorage-independent growth in human glioblastoma cell lines and enhances temozolomide's antiproliferative effect.Novel Approaches to Apoptosis-Inducing Therapies.RIST: a potent new combination therapy for glioblastoma.Artesunate enhances the antiproliferative effect of temozolomide on U87MG and A172 glioblastoma cell lines.Transitory dasatinib-resistant states in KIT(mut) t(8;21) acute myeloid leukemia cells correlate with altered KIT expression.Inhibition of NF-κB signaling ablates the invasive phenotype of glioblastoma.v-Src-induced modulation of the calpain-calpastatin proteolytic system regulates transformation.The pyridinylfuranopyrimidine inhibitor, PI-103, chemosensitizes glioblastoma cells for apoptosis by inhibiting DNA repair.Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin.Sensitization for gamma-irradiation-induced apoptosis by second mitochondria-derived activator of caspase.A paired comparison between glioblastoma "stem cells" and differentiated cells.Mitochondrial matrix chaperone and c-myc inhibition causes enhanced lethality in glioblastoma.BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma.KIT mutations in primary mediastinal B-cell lymphoma.Antiviral vaccines license T cell responses by suppressing granzyme B levels in human plasmacytoid dendritic cells.Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling.A novel role for FAK as a protease-targeting adaptor protein: regulation by p42 ERK and Src.Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- and drug-induced apoptosis.4-hydroperoxy-cyclophosphamide mediates caspase-independent T-cell apoptosis involving oxidative stress-induced nuclear relocation of mitochondrial apoptogenic factors AIF and EndoG.The effects of PI3K-mediated signalling on glioblastoma cell behaviour.Cell death-based treatment of childhood cancer.Blocking distinct interactions between Glioblastoma cells and their tissue microenvironment: A novel multi-targeted therapeutic approach.Inhibition of Bcl-2/Bcl-xL and c-MET causes synthetic lethality in model systems of glioblastoma.Radiation and Brain Tumors: An Overview.NF-kappaB-independent sensitization of glioblastoma cells for TRAIL-induced apoptosis by proteasome inhibition.Inhibition of PI3K signalling increases the efficiency of radiotherapy in glioblastoma cellsViability of glioblastoma stem cells is effectively reduced by diisothiocyanate-derived mercapturic acids
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P50
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researcher
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wetenschapper
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հետազոտող
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Mike-Andrew Westhoff
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Mike-Andrew Westhoff
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Mike-Andrew Westhoff
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Mike-Andrew Westhoff
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Mike-Andrew Westhoff
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Mike-Andrew Westhoff
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Mike-Andrew Westhoff
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Mike-Andrew Westhoff
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Mike-Andrew Westhoff
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Mike-Andrew Westhoff
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Mike-Andrew Westhoff
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Mike-Andrew Westhoff
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Mike-Andrew Westhoff
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Mike-Andrew Westhoff
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Mike-Andrew Westhoff
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P106
P1153
56354861500
P21
P31
P496
0000-0003-3256-7100