The expression of a high level of morphine antinociceptive tolerance in mice involves both PKC and PKA.
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Opioid modulation of GABA release in the rat inferior colliculus.Increased glutamate synaptic transmission in the nucleus raphe magnus neurons from morphine-tolerant ratsAgonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization.The effect of protein kinase C and G protein-coupled receptor kinase inhibition on tolerance induced by mu-opioid agonists of different efficacyFunctional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance.Region-dependent attenuation of mu opioid receptor-mediated G-protein activation in mouse CNS as a function of morphine tolerance.Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.Protein kinase C in pain: involvement of multiple isoformsMorphine tolerance in the mouse ileum and colonContribution of acid sphingomyelinase in the periaqueductal gray region to morphine-induced analgesia in mice.Evidence for an important role of protein phosphatases in the mechanism of morphine tolerancePre-treatment with a PKC or PKA inhibitor prevents the development of morphine tolerance but not physical dependence in mice.Heterologous regulation of agonist-independent μ-opioid receptor phosphorylation by protein kinase CRole of protein kinase C and mu-opioid receptor (MOPr) desensitization in tolerance to morphine in rat locus coeruleus neurons.Sevoflurane inhibits the µ-opioid receptor function expressed in Xenopus oocytes.Ethanol Reversal of Oxycodone Tolerance in Dorsal Root Ganglia Neurons.
P2860
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P2860
The expression of a high level of morphine antinociceptive tolerance in mice involves both PKC and PKA.
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The expression of a high level ...... ice involves both PKC and PKA.
@en
The expression of a high level ...... ice involves both PKC and PKA.
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The expression of a high level ...... ice involves both PKC and PKA.
@en
The expression of a high level ...... ice involves both PKC and PKA.
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The expression of a high level ...... ice involves both PKC and PKA.
@en
The expression of a high level ...... ice involves both PKC and PKA.
@nl
P2093
P1433
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The expression of a high level ...... ice involves both PKC and PKA.
@en
P2093
Forrest L Smith
Mark J Elzey
Ruby R Javed
William L Dewey
P356
10.1016/S0006-8993(03)03170-6
P407
P577
2003-09-01T00:00:00Z