Biochemical evidence that glycine allosterically regulates an NMDA receptor-coupled ion channel.
about
Enantiomers of HA-966 (3-amino-1-hydroxypyrrolid-2-one) exhibit distinct central nervous system effects: (+)-HA-966 is a selective glycine/N-methyl-D-aspartate receptor antagonist, but (-)-HA-966 is a potent gamma-butyrolactone-like sedative7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complexModulation of seizure susceptibility in the mouse by the strychnine-insensitive glycine recognition site of the NMDA receptor/ion channel complex.Interaction of [3H]MK-801 with multiple states of the N-methyl-D-aspartate receptor complex of rat brainCycloleucine blocks NMDA responses in cultured hippocampal neurones under voltage clamp: antagonism at the strychnine-insensitive glycine receptorRegional variations in [3H]MK801 binding to rat brain N-methyl-D-aspartate receptors.6,7-Dichloroquinoxaline-2,3-dione is a competitive antagonist specific to strychnine-insensitive [3H]glycine binding sites on the N-methyl-D-aspartate receptor complex.[3H]N-[1-(2-thienyl)cyclohexyl]-3,4-piperidine ([3H]TCP) binding in human frontal cortex: decreases in Alzheimer-type dementia.Alteration of [3H]MK-801 binding associated with the N-methyl-D-Aspartate receptor complex by acute ethanol in rat cortex and hippocampus in vitro.Inhibition by calmodulin antagonists of [3H]MK-801 binding in brain synaptic membranes.Glycine binding to rat cortex and spinal cord: binding characteristics and pharmacology reveal distinct populations of sites.Characterization of a [3H]glycine recognition site as a modulatory site of the N-methyl-D-aspartate receptor complex.[3H]thienylcyclohexylpiperidine binding activity in brain synaptic membranes treated with Triton X-100.Support for radiolabeling of a glycine recognition domain on the N-methyl-D-aspartate receptor ionophore complex by 5,7-[3H]dichlorokynurenate in rat brain.Differential modulation by divalent cations of [3H]MK-801 binding in brain synaptic membranes.Characterisation of the glycine modulatory site of the N-methyl-D-aspartate receptor-ionophore complex in human brain.Solubilization of spermidine-sensitive (+)-[3H]5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine ([3H]MK-801) binding activity from rat brain.Interaction of strychnine-insensitive glycine binding with MK-801 binding in brain synaptic membranes.Polyamine binding sites in the rat brain hippocampus plasma membranes: MK 801 does not influence the binding process.Reduced glycine stimulation of [3H]MK-801 binding in Alzheimer's disease.Glycine potentiates the stimulation of inositol phospholipid hydrolysis by excitatory amino acids in primary cultures of cerebellar neurons.
P2860
Q24559913-9B81628B-AC9F-4160-A16A-9EEB5C1FD41DQ24649753-3C6EE5CD-E87B-4649-9789-09124786B67CQ30498832-1BEC4D56-CEE1-485C-BEF2-E5B52F81FCB8Q33833341-90B6313C-6874-4954-A393-6291927F2536Q35756891-9B6D0CCE-EC92-45B8-85BB-FB76F8553E82Q41152098-E7F9F632-50F3-420B-B55E-55F327C46969Q41841697-E82A83C5-1A3D-4E7D-8F16-CA551B4A83CAQ41893432-8FBDCF2B-8628-4A48-A87D-1013AFB56709Q42481022-954C4E63-49EB-4FF9-9EA3-B770867EE25AQ44188383-A4260FF3-9126-4080-B739-4D6B276EBDBDQ44775760-E5D154BE-EE89-45FA-BC1C-B1D153BFF36AQ44933835-67F4100C-F66D-4453-B127-A3AD40F27605Q46023723-983A0548-CC2A-40B9-ACEE-0F37EF146F2FQ48340520-DFD2E55C-E97D-40D5-B6E0-111C660C1745Q48451782-FA34990E-A7D8-407A-9E91-F933E778C33BQ48827287-F1B29BA3-918D-41C7-A564-3DD87CA0C118Q48874346-6F51D435-0BCE-4D80-A75E-A362795DE2A7Q48943495-3DFA0FCB-D095-43F6-A388-0282E7EF88F7Q48945398-7968E527-139A-4576-A956-103CFCADE2FEQ53187649-97E0359B-AD18-46AC-9B61-46FDC9D21413Q53855715-CC19749A-A6C2-4A94-8417-03A572BFBA8D
P2860
Biochemical evidence that glycine allosterically regulates an NMDA receptor-coupled ion channel.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
1987年學術文章
@zh-hant
name
Biochemical evidence that glyc ...... receptor-coupled ion channel.
@en
Biochemical evidence that glyc ...... receptor-coupled ion channel.
@nl
type
label
Biochemical evidence that glyc ...... receptor-coupled ion channel.
@en
Biochemical evidence that glyc ...... receptor-coupled ion channel.
@nl
prefLabel
Biochemical evidence that glyc ...... receptor-coupled ion channel.
@en
Biochemical evidence that glyc ...... receptor-coupled ion channel.
@nl
P2093
P1476
Biochemical evidence that glyc ...... receptor-coupled ion channel.
@en
P2093
P304
P356
10.1016/0014-2999(87)90096-3
P407
P577
1987-10-01T00:00:00Z