Docking studies on alphavbeta3 integrin ligands: pharmacophore refinement and implications for drug design.
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Calpha-H...O = C hydrogen bonds contribute to the specificity of RGD cell-adhesion interactionsHow the headpiece hinge angle is opened: New insights into the dynamics of integrin activation.High Affinity vs. Native Fibronectin in the Modulation of αvβ3 Integrin Conformational Dynamics: Insights from Computational Analyses and Implications for Molecular DesignRGD-avidin-biotin pretargeting to alpha v beta 3 integrin enhances the proapoptotic activity of TNF alpha related apoptosis inducing ligand (TRAIL).Integrin activation dynamics between the RGD-binding site and the headpiece hinge.Integrin targeted drug and gene delivery.N-methylation of peptides and proteins: an important element for modulating biological functions.Isocyanide-based multicomponent reactions towards cyclic constrained peptidomimetics.Integrin Ligands with α/β-Hybrid Peptide Structure: Design, Bioactivity, and Conformational Aspects.αvβ3- or α5β1-Integrin-Selective Peptidomimetics for Surface Coating.Amide-to-ester substitution allows fine-tuning of the cyclopeptide conformational ensemble.PAMAM-RGD conjugates enhance siRNA delivery through a multicellular spheroid model of malignant glioma.Structural basis for the interaction of isoDGR with the RGD-binding site of alphavbeta3 integrin.A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins.Domain-selective ligand-binding modes and atomic level pharmacophore refinement in angiotensin I converting enzyme (ACE) inhibitors.Spectroscopic Evidence of Phosphorous Heterocycle-DNA Interaction and its Verification by Docking Approach.High-Affinity "Click" RGD Peptidomimetics as Radiolabeled Probes for Imaging αv β3 Integrin.Recent Innovations in Peptide Based Targeted Drug Delivery to Cancer Cells.Conjugates of Cell Adhesion Peptides for Therapeutics and Diagnostics Against Cancer and Autoimmune Diseases.Cyclic RGD β-Lactam Peptidomimetics Induce Differential Gene Expression in Human Endothelial CellsAn insight of spirooxindole-annulated thiopyran – DNA interaction: spectroscopic and docking approach of these biological materials
P2860
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P2860
Docking studies on alphavbeta3 integrin ligands: pharmacophore refinement and implications for drug design.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
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2003年學術文章
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name
Docking studies on alphavbeta3 ...... implications for drug design.
@en
Docking studies on alphavbeta3 ...... implications for drug design.
@nl
type
label
Docking studies on alphavbeta3 ...... implications for drug design.
@en
Docking studies on alphavbeta3 ...... implications for drug design.
@nl
prefLabel
Docking studies on alphavbeta3 ...... implications for drug design.
@en
Docking studies on alphavbeta3 ...... implications for drug design.
@nl
P50
P356
P1476
Docking studies on alphavbeta3 ...... implications for drug design.
@en
P2093
Horst Kessler
Kay-E Gottschalk
P304
P356
10.1021/JM020577M
P407
P577
2003-10-01T00:00:00Z