Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B.
about
53BP2S, interacting with insulin receptor substrates, modulates insulin signalingKinetic mechanism of AKT/PKB enzyme familyClipR-59 interacts with Akt and regulates Akt cellular compartmentalizationVEGF stimulation of mitochondrial biogenesis: requirement of AKT3 kinaseExploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3Identification of filamin C as a new physiological substrate of PKBalpha using KESTRELAS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domainNuclear Akt interacts with B23/NPM and protects it from proteolytic cleavage, enhancing cell survivalLife with a single isoform of Akt: mice lacking Akt2 and Akt3 are viable but display impaired glucose homeostasis and growth deficienciesGlucose Transporters in Cardiac Metabolism and HypertrophyThe critical role of Akt in cardiovascular functionRole for Akt3/protein kinase Bgamma in attainment of normal brain sizeInsulin-modulated Akt subcellular localization determines Akt isoform-specific signaling.Molecular and genetic studies imply Akt-mediated signaling promotes protein kinase CbetaII alternative splicing via phosphorylation of serine/arginine-rich splicing factor SRp40Role of insulin-like growth factor-binding protein 5 (IGFBP5) in organismal and pancreatic beta-cell growthInsulin signaling diverges into Akt-dependent and -independent signals to regulate the recruitment/docking and the fusion of GLUT4 vesicles to the plasma membraneTropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling.Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells.Maternal melatonin programs the daily pattern of energy metabolism in adult offspring.Targeting the PI3K/AKT/mTOR signaling network in acute myelogenous leukemia.Differential effects of protein kinase B/Akt isoforms on glucose homeostasis and islet mass.Serum- and glucocorticoid-inducible kinase 1 (SGK1) regulates adipocyte differentiation via forkhead box O1.The GLUT4 codeRictor/mTORC2 facilitates central regulation of energy and glucose homeostasis.Signaling specificity in the Akt pathway in biology and disease.The critical role of AKT2 in hepatic steatosis induced by PTEN loss.Akt2 knockout alleviates prolonged caloric restriction-induced change in cardiac contractile function through regulation of autophagy.The ontogeny of insulin signaling in the preterm baboon model.Insulin resistance for glucose uptake and Akt2 phosphorylation in the soleus, but not epitrochlearis, muscles of old vs. adult ratsA phase I study of nelfinavir concurrent with temozolomide and radiotherapy in patients with glioblastoma multiforme.The phosphatidylinositol 3-kinase/Akt/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients.Metabolic syndrome and insulin resistance: underlying causes and modification by exercise training.Knockdown of the fat mass and obesity gene disrupts cellular energy balance in a cell-type specific manner.EGFR-mutated lung cancer: a paradigm of molecular oncology.Insulin signaling and insulin sensitizing in muscle and liver of obese monkeys: peroxisome proliferator-activated receptor gamma agonist improves defective activation of atypical protein kinase C.Impact of GLO1 knock down on GLUT4 trafficking and glucose uptake in L6 myoblasts.An early response transcription factor, Egr-1, enhances insulin resistance in type 2 diabetes with chronic hyperinsulinismHematopoietic Akt2 deficiency attenuates the progression of atherosclerosis.Mechanisms for increased insulin-stimulated Akt phosphorylation and glucose uptake in fast- and slow-twitch skeletal muscles of calorie-restricted ratsHyperinsulinemia leads to uncoupled insulin regulation of the GLUT4 glucose transporter and the FoxO1 transcription factor
P2860
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P2860
Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B.
@en
Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B.
@nl
type
label
Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B.
@en
Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B.
@nl
prefLabel
Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B.
@en
Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B.
@nl
P356
P1476
Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B
@en
P2093
P304
49530-49536
P356
10.1074/JBC.M306782200
P407
P577
2003-09-30T00:00:00Z