RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity.
about
MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survivalJNK Signaling: Regulation and Functions Based on Complex Protein-Protein PartnershipsA RING to rule them all? Insights into the Map3k1 PHD motif provide a new mechanistic understanding into the diverse roles of Map3k1Apoptosis induced by cytoskeletal disruption requires distinct domains of MEKK1Inhibition of MLC phosphorylation restricts replication of influenza virus--a mechanism of action for anti-influenza agentsEpithelial sheet movement requires the cooperation of c-Jun and MAP3K1CCR7-mediated c-Jun N-terminal kinase activation regulates cell migration in mature dendritic cellsRhoA regulation of NF-kappaB activation is mediated by COX-2-dependent feedback inhibition of IKK in kidney epithelial cellsGene-Environment Interactions Target Mitogen-activated Protein 3 Kinase 1 (MAP3K1) Signaling in Eyelid MorphogenesisMyosin-II negatively regulates minor process extension and the temporal development of neuronal polarity.The c-jun kinase/stress-activated pathway: regulation, function and role in human disease.Deltex regulates T-cell activation by targeted degradation of active MEKK1.Mutations in MAP3K1 cause 46,XY disorders of sex development and implicate a common signal transduction pathway in human testis determinationMitogen-activated protein kinase kinase kinase 1 (MAP3K1) integrates developmental signals for eyelid closureWiring diagrams of MAPK regulation by MEKK1, 2, and 3.Oncogenic Ras in tumour progression and metastasis.Minireview: Mouse Models of Rho GTPase Function in Mammary Gland Development, Tumorigenesis, and MetastasisRole of mitogen-activated protein kinase kinase kinases in signal integration.Rho GTPase-activating bacterial toxins: from bacterial virulence regulation to eukaryotic cell biology.RhoA modulates functional and physical interaction between ROCK1 and Erk1/2 in selenite-induced apoptosis of leukaemia cells.The small GTPase RhoA is crucial for MC3T3-E1 osteoblastic cell survival.Proteinase-activated receptor 2 expression in breast cancer and its role in breast cancer cell migration.JNK: a stress-activated protein kinase therapeutic strategies and involvement in Alzheimer's and various neurodegenerative abnormalities.c-Jun, at the crossroad of the signaling network.Inhibition and termination of physiological responses by GTPase activating proteins.RhoA inhibits the hypoxia-induced apoptosis and mitochondrial dysfunction in chondrocytes via positively regulating the CREB phosphorylation.Mutations in MAP3K1 tilt the balance from SOX9/FGF9 to WNT/β-catenin signaling.Active stress kinases in proliferating endothelial cells associated with cytoskeletal structures.MEKK1 transduces activin signals in keratinocytes to induce actin stress fiber formation and migration.MAP3K1: Genomic Alterations in Cancer and Function in Promoting Cell Survival or Apoptosis.Contributions of the RhoGEF activity of p210 BCR/ABL to disease progression.Hyperosmotically induced accumulation of a phosphorylated p38-like MAPK involved in protoplast volume regulation of plasmolyzed wheat root cells.G alpha 13 signals via p115RhoGEF cascades regulating JNK1 and primitive endoderm formation.Simulation of the regulation of EGFR endocytosis and EGFR-ERK signaling by endophilin-mediated RhoA-EGFR crosstalk.Rapidly screening variants of uncertain significance in the MAP3K1 gene for phenotypic effects.
P2860
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P2860
RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity.
@en
RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity.
@nl
type
label
RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity.
@en
RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity.
@nl
prefLabel
RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity.
@en
RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity.
@nl
P2093
P2860
P356
P1476
RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity.
@en
P2093
Ewen D Gallagher
Paul C Sternweis
Stephen Gutowski
P2860
P304
P356
10.1074/JBC.M309525200
P407
P577
2003-10-27T00:00:00Z