Alpha-conotoxins EpI and AuIB switch subtype selectivity and activity in native versus recombinant nicotinic acetylcholine receptors.
about
Alpha-conotoxins as pharmacological probes of nicotinic acetylcholine receptors.Alpha-conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of alpha3beta4 nicotinic acetylcholine receptors.Chemical synthesis and characterization of two α4/7-conotoxinsPhysico-chemical characterization and synthesis of neuronally active alpha-conotoxins.Modulation of conotoxin structure and function is achieved through a multienzyme complex in the venom glands of cone snails.Number and locations of agonist binding sites required to activate homomeric Cys-loop receptorsSynthetic α-conotoxin mutants as probes for studying nicotinic acetylcholine receptors and in the development of novel drug leads.From toxins targeting ligand gated ion channels to therapeutic molecules.Conotoxin therapeutics: a pipeline for success?
P2860
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P2860
Alpha-conotoxins EpI and AuIB switch subtype selectivity and activity in native versus recombinant nicotinic acetylcholine receptors.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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name
Alpha-conotoxins EpI and AuIB ...... tinic acetylcholine receptors.
@en
Alpha-conotoxins EpI and AuIB ...... tinic acetylcholine receptors.
@nl
type
label
Alpha-conotoxins EpI and AuIB ...... tinic acetylcholine receptors.
@en
Alpha-conotoxins EpI and AuIB ...... tinic acetylcholine receptors.
@nl
prefLabel
Alpha-conotoxins EpI and AuIB ...... tinic acetylcholine receptors.
@en
Alpha-conotoxins EpI and AuIB ...... tinic acetylcholine receptors.
@nl
P2093
P2860
P1433
P1476
Alpha-conotoxins EpI and AuIB ...... tinic acetylcholine receptors.
@en
P2093
Alfred Maelicke
Annette Nicke
Marek Samochocki
Marion L Loughnan
Paramjit S Bansal
P2860
P304
P356
10.1016/S0014-5793(03)01161-X
P407
P577
2003-11-01T00:00:00Z