2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo.
about
Targeting cellular metabolism to improve cancer therapeuticsChronic ingestion of 2-deoxy-D-glucose induces cardiac vacuolization and increases mortality in ratsRedox-directed cancer therapeutics: molecular mechanisms and opportunitiesA new view of carcinogenesis and an alternative approach to cancer therapyJasmonates induce nonapoptotic death in high-resistance mutant p53-expressing B-lymphoma cellsThe sweet trap in tumors: aerobic glycolysis and potential targets for therapyMitochondrial targets for pharmacological intervention in human diseaseNovel therapeutic targets of tumor metabolismCancer cell metabolism: implications for therapeutic targetsAppetite for destruction: the inhibition of glycolysis as a therapy for tuberous sclerosis complex-related tumorsTargeting glycogen metabolism in bladder cancerSynergism of ursolic acid derivative US597 with 2-deoxy-D-glucose to preferentially induce tumor cell death by dual-targeting of apoptosis and glycolysis.HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epitheliumCombined inhibition of glycolysis and AMPK induces synergistic breast cancer cell killing.Heterogeneity of glycolysis in cancers and therapeutic opportunities.Molecular Connections between Cancer Cell Metabolism and the Tumor MicroenvironmentA phase I dose-escalation trial of 2-deoxy-D-glucose alone or combined with docetaxel in patients with advanced solid tumorsEfficient elimination of cancer cells by deoxyglucose-ABT-263/737 combination therapyInhibition of lipolysis by mercaptoacetate and etomoxir specifically sensitize drug-resistant lung adenocarcinoma cell to paclitaxelAscorbic acid and a cytostatic inhibitor of glycolysis synergistically induce apoptosis in non-small cell lung cancer cellsNew aspects of an old drug--diclofenac targets MYC and glucose metabolism in tumor cellsDichloroacetate enhances adriamycin-induced hepatoma cell toxicity in vitro and in vivo by increasing reactive oxygen species levelsThe ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant gliomaCombining 2-deoxy-D-glucose with fenofibrate leads to tumor cell death mediated by simultaneous induction of energy and ER stress2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human melanoma cells through XBP-1-mediated up-regulation of TRAIL-R2Bioenergetic properties of human sarcoma cells help define sensitivity to metabolic inhibitors.p53 is an important factor for the radiosensitization effect of 2-deoxy-D-glucoseAntiangiogenic activity of 2-deoxy-D-glucose.Paclitaxel combined with inhibitors of glucose and hydroperoxide metabolism enhances breast cancer cell killing via H2O2-mediated oxidative stress.Akt and c-Myc differentially activate cellular metabolic programs and prime cells to bioenergetic inhibition.Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomasProfiling and targeting of cellular bioenergetics: inhibition of pancreatic cancer cell proliferation.Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment.A validated bioanalytical HPLC method for pharmacokinetic evaluation of 2-deoxyglucose in human plasma.Anticancer targets in the glycolytic metabolism of tumors: a comprehensive reviewTargeting tumor metabolism with 2-deoxyglucose in patients with castrate-resistant prostate cancer and advanced malignancies.Phosphorylation of eIF2α at serine 51 is an important determinant of cell survival and adaptation to glucose deficiency.Can short-term fasting protect against doxorubicin-induced cardiotoxicity?JC virus T-antigen regulates glucose metabolic pathways in brain tumor cells.On-target inhibition of tumor fermentative glycolysis as visualized by hyperpolarized pyruvate.
P2860
Q24596727-5CFABC16-C4CD-4EC1-9A8A-2923881A5D47Q24634601-478F3361-64BB-4353-AA57-F779335EFEF8Q24645584-23B16A34-6149-432D-9B0F-AF8A1AD32F6EQ24650249-7F7AA871-0F9B-4541-BF01-91B5FF74C96AQ24676240-C4A136A2-024E-4980-8418-15FBBB24F016Q26766079-2F8AF550-6C83-4D3F-B531-55F56E279B63Q26824514-220292D9-3B3E-4419-876F-BBAEB43C8F59Q27005930-45ACA544-9A36-45BE-9AE2-B0BD4C8A6577Q27013632-6F82E632-E0C9-4511-87C1-6A56FBEA31D4Q27015394-F8816B44-859F-4E33-8BFA-715A4D579FE2Q27025144-7FBCE958-D7BC-4D54-8BB0-91A611BD4F74Q27309197-F8BD0CF6-96F9-4486-AC76-B1B705D7E0EBQ27316863-FEF65F95-7B54-443B-87D5-13381BEA4B77Q27317158-6AFBE178-C983-4FDF-BE01-263A94CB27D6Q27693375-3204A729-4E7B-4652-91D1-E757A5DAAB1BQ28081657-03B9918E-E92F-4EA5-99FA-F80A0CED7FE9Q28281237-C9162DB9-2A73-4FC4-B770-500ECC18AB14Q28477131-06128620-F275-4966-B8CE-60C0B3C55908Q28533247-5233760F-D916-4BBE-8780-866112E562D3Q28533798-AFC6CB24-E40F-4006-A60C-6821A13B4CBAQ28534587-E1E2D429-1107-4F29-9748-1D142E5466C2Q28537767-939A0C82-DF08-47BC-B2DA-0A13C3D6E383Q28730187-80DAE208-34D6-49F4-B959-C883572D8DB8Q30054496-32265E6E-33AB-410A-AC57-94E8E8F3F2AFQ33578562-7F4B91A3-8F4A-41F2-B6C5-90C2FAC48243Q33578594-E2ABF07A-3D6B-468D-939D-5664276F9E30Q33586467-43755CB3-19BA-4352-BF33-3FB852378005Q33742196-3D9AEF2F-8C1A-4CD1-B06D-90F793BE1D5AQ33746588-C0DC4807-749A-4443-9F1A-72A7F4F08F20Q33748081-694AB5DC-619D-476A-855E-C3FE0EFDA300Q33759272-3045C9B1-DCC2-4A80-974C-9A55B48DDBAFQ33877459-DE69EC26-A068-4F4F-8896-2A90BA62D227Q34007740-166229DB-AE3B-483E-8D27-D8BB9BBC4237Q34024304-5601BC0A-A3DF-45AA-A032-2C15399D9764Q34028478-FD6202C0-E45E-46D7-A211-FA75707A93C6Q34081705-41EDB698-A875-4513-8CB1-82DC147231A8Q34123406-953CE904-F620-4A43-A923-E7A447A83E09Q34161559-C59DBFA7-7ECB-4164-9E2B-7332A8DAE05EQ34230468-D532C887-2CFC-4ED8-B8CF-CB145973B6C3Q34498003-DEF5B374-2505-4068-B05F-E3A8E92EA446
P2860
2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
2-deoxy-D-glucose increases th ...... all cell lung cancers in vivo.
@en
2-deoxy-D-glucose increases th ...... all cell lung cancers in vivo.
@nl
type
label
2-deoxy-D-glucose increases th ...... all cell lung cancers in vivo.
@en
2-deoxy-D-glucose increases th ...... all cell lung cancers in vivo.
@nl
prefLabel
2-deoxy-D-glucose increases th ...... all cell lung cancers in vivo.
@en
2-deoxy-D-glucose increases th ...... all cell lung cancers in vivo.
@nl
P2093
P1433
P1476
2-deoxy-D-glucose increases th ...... all cell lung cancers in vivo.
@en
P2093
George F Tidmarsh
Gregory Maschek
Kara Hamilton
Linda R De Young
Niramol Savaraj
Paul Braunschweiger
Theodore J Lampidis
Waldemar Priebe
P356
10.1158/0008-5472.CAN-03-3294
P407
P577
2004-01-01T00:00:00Z