2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo. - Wikidata - wikimedia - TriplyDB

2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo.

2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo.

http://www.wikidata.org/entity/Q44732835

about

Targeting cellular metabolism to improve cancer therapeutics Chronic ingestion of 2-deoxy-D-glucose induces cardiac vacuolization and increases mortality in rats Redox-directed cancer therapeutics: molecular mechanisms and opportunities A new view of carcinogenesis and an alternative approach to cancer therapy Jasmonates induce nonapoptotic death in high-resistance mutant p53-expressing B-lymphoma cells The sweet trap in tumors: aerobic glycolysis and potential targets for therapy Mitochondrial targets for pharmacological intervention in human disease Novel therapeutic targets of tumor metabolism Cancer cell metabolism: implications for therapeutic targets Appetite for destruction: the inhibition of glycolysis as a therapy for tuberous sclerosis complex-related tumors Targeting glycogen metabolism in bladder cancer Synergism of ursolic acid derivative US597 with 2-deoxy-D-glucose to preferentially induce tumor cell death by dual-targeting of apoptosis and glycolysis.HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium Combined inhibition of glycolysis and AMPK induces synergistic breast cancer cell killing.Heterogeneity of glycolysis in cancers and therapeutic opportunities.Molecular Connections between Cancer Cell Metabolism and the Tumor Microenvironment A phase I dose-escalation trial of 2-deoxy-D-glucose alone or combined with docetaxel in patients with advanced solid tumors Efficient elimination of cancer cells by deoxyglucose-ABT-263/737 combination therapy Inhibition of lipolysis by mercaptoacetate and etomoxir specifically sensitize drug-resistant lung adenocarcinoma cell to paclitaxel Ascorbic acid and a cytostatic inhibitor of glycolysis synergistically induce apoptosis in non-small cell lung cancer cells New aspects of an old drug--diclofenac targets MYC and glucose metabolism in tumor cells Dichloroacetate enhances adriamycin-induced hepatoma cell toxicity in vitro and in vivo by increasing reactive oxygen species levels The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma Combining 2-deoxy-D-glucose with fenofibrate leads to tumor cell death mediated by simultaneous induction of energy and ER stress 2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human melanoma cells through XBP-1-mediated up-regulation of TRAIL-R2 Bioenergetic properties of human sarcoma cells help define sensitivity to metabolic inhibitors.p53 is an important factor for the radiosensitization effect of 2-deoxy-D-glucose Antiangiogenic activity of 2-deoxy-D-glucose.Paclitaxel combined with inhibitors of glucose and hydroperoxide metabolism enhances breast cancer cell killing via H2O2-mediated oxidative stress.Akt and c-Myc differentially activate cellular metabolic programs and prime cells to bioenergetic inhibition.Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomas Profiling and targeting of cellular bioenergetics: inhibition of pancreatic cancer cell proliferation.Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment.A validated bioanalytical HPLC method for pharmacokinetic evaluation of 2-deoxyglucose in human plasma.Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review Targeting tumor metabolism with 2-deoxyglucose in patients with castrate-resistant prostate cancer and advanced malignancies.Phosphorylation of eIF2α at serine 51 is an important determinant of cell survival and adaptation to glucose deficiency.Can short-term fasting protect against doxorubicin-induced cardiotoxicity?JC virus T-antigen regulates glucose metabolic pathways in brain tumor cells.On-target inhibition of tumor fermentative glycolysis as visualized by hyperpolarized pyruvate.

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2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo.

http://www.wikidata.org/entity/Q44732835

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2004 nî lūn-bûn

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2-deoxy-D-glucose increases th ...... all cell lung cancers in vivo.

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2-deoxy-D-glucose increases th ...... all cell lung cancers in vivo.

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2-deoxy-D-glucose increases th ...... all cell lung cancers in vivo.

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2-deoxy-D-glucose increases th ...... all cell lung cancers in vivo.

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0008-5472.CAN-03-3294

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Cancer Research

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George F Tidmarsh

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Gregory Maschek

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Kara Hamilton

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Linda R De Young

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Niramol Savaraj

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31-34

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10.1158/0008-5472.CAN-03-3294

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1

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