Targeting modular polyketide synthases with iteratively acting acyltransferases from metagenomes of uncultured bacterial consortia.
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Discovery Strategies of Bioactive Compounds Synthesized by Nonribosomal Peptide Synthetases and Type-I Polyketide Synthases Derived from Marine Microbiomes.Bioprospecting Sponge-Associated Microbes for Antimicrobial CompoundsTargeted metagenomics as a tool to tap into marine natural product diversity for the discovery and production of drug candidatesStructure and Mechanism of the trans -Acting Acyltransferase from the Disorazole SynthaseEvolutionary implications of bacterial polyketide synthasesPathogenic fungus harbours endosymbiotic bacteria for toxin productionStrategies for discovery and improvement of enzyme function: state of the art and opportunitiesSponge-associated microorganisms: evolution, ecology, and biotechnological potential.Widespread occurrence and genomic context of unusually small polyketide synthase genes in microbial consortia associated with marine spongesMetagenomic analysis reveals diverse polyketide synthase gene clusters in microorganisms associated with the marine sponge Discodermia dissoluta.Natural products from marine organisms and their associated microbes.Characterization of a forest soil metagenome clone that confers indirubin and indigo production on Escherichia coliDiversity of microbes associated with the marine sponge, Haliclona simulans, isolated from Irish waters and identification of polyketide synthase genes from the sponge metagenome.Enriching plant microbiota for a metagenomic library construction.From bacterial genomics to metagenomics: concept, tools and recent advances.Deep sequencing of non-ribosomal peptide synthetases and polyketide synthases from the microbiomes of Australian marine sponges.Diversity and biotechnological potential of microorganisms associated with marine sponges.Polyketide synthases in the microbiome of the marine sponge Plakortis halichondrioides: a metagenomic updateType I polyketide synthases that require discrete acyltransferases.Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthasesMultimodular type I polyketide synthases in algae evolve by module duplications and displacement of AT domains in trans.Metagenomic Analysis of the Sponge Discodermia Reveals the Production of the Cyanobacterial Natural Product Kasumigamide by 'Entotheonella'.Polyketides in insects: ecological role of these widespread chemicals and evolutionary aspects of their biogenesis.Structural analysis of protein-protein interactions in type I polyketide synthasesMetabolites from symbiotic bacteria.iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.Polyketide genes in the marine sponge Plakortis simplex: a new group of mono-modular type I polyketide synthases from sponge symbionts.Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei.Engineering the acyltransferase substrate specificity of assembly line polyketide synthases.Polyketide synthase gene diversity within the microbiome of the sponge Arenosclera brasiliensis, endemic to the Southern Atlantic Ocean.Insights into the evolution of macrolactam biosynthesis through cloning and comparative analysis of the biosynthetic gene cluster for a novel macrocyclic lactam, ML-449Antibacterial aryl-crowned polyketide from Bacillus subtilis associated with seaweed Anthophycus longifolius.O-heterocyclic derivatives with antibacterial properties from marine bacterium Bacillus subtilis associated with seaweed, Sargassum myriocystum.Phylogenetically diverse cultivable fungal community and polyketide synthase (PKS), non-ribosomal peptide synthase (NRPS) genes associated with the South China Sea sponges.Co-cultures of Pseudomonas aeruginosa and Roseobacter denitrificans reveal shifts in gene expression levels compared to solo cultures.Introduction to the Global Scenario of Marine Sponge Research
P2860
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P2860
Targeting modular polyketide synthases with iteratively acting acyltransferases from metagenomes of uncultured bacterial consortia.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Targeting modular polyketide s ...... ncultured bacterial consortia.
@en
Targeting modular polyketide s ...... ncultured bacterial consortia.
@nl
type
label
Targeting modular polyketide s ...... ncultured bacterial consortia.
@en
Targeting modular polyketide s ...... ncultured bacterial consortia.
@nl
prefLabel
Targeting modular polyketide s ...... ncultured bacterial consortia.
@en
Targeting modular polyketide s ...... ncultured bacterial consortia.
@nl
P2093
P2860
P1476
Targeting modular polyketide s ...... ncultured bacterial consortia.
@en
P2093
Dequan Hui
Nobuhiro Fusetani
Shigeki Matsunaga
P2860
P304
P356
10.1111/J.1462-2920.2004.00531.X
P577
2004-09-01T00:00:00Z