Lilly lecture 2003: the struggle for mastery in insulin action: from triumvirate to republic.
about
FoxO1 haploinsufficiency protects against high-fat diet-induced insulin resistance with enhanced peroxisome proliferator-activated receptor gamma activation in adipose tissueA Foxo/Notch pathway controls myogenic differentiation and fiber type specificationAndrogen receptor (AR) pathophysiological roles in androgen-related diseases in skin, bone/muscle, metabolic syndrome and neuron/immune systems: lessons learned from mice lacking AR in specific cellsHepatocyte growth factor family negatively regulates hepatic gluconeogenesis via induction of orphan nuclear receptor small heterodimer partner in primary hepatocytesSoyasaponins can blunt inflammation by inhibiting the reactive oxygen species-mediated activation of PI3K/Akt/NF-kB pathwayA small amount of dietary carbohydrate can promote the HFD-induced insulin resistance to a maximal levelExposure to excess insulin (glargine) induces type 2 diabetes mellitus in mice fed on a chow diet.Prolonged exposure to insulin induces mitochondrion-derived oxidative stress through increasing mitochondrial cholesterol content in hepatocytes.Insulin and insulin signaling play a critical role in fat induction of insulin resistance in mouse.Constitutive role for IRE1α-XBP1 signaling pathway in the insulin-mediated hepatic lipogenic programFine-tuned regulation of the PGC-1α gene transcription by different intracellular signaling pathways.Hepatic autophagy is suppressed in the presence of insulin resistance and hyperinsulinemia: inhibition of FoxO1-dependent expression of key autophagy genes by insulin.Insulin is a stronger inducer of insulin resistance than hyperglycemia in mice with type 1 diabetes mellitus (T1DM).Increased basal level of Akt-dependent insulin signaling may be responsible for the development of insulin resistanceProlonged exposure to insulin suppresses mitochondrial production in primary hepatocytesInhibition of gluconeogenesis in primary hepatocytes by stromal cell-derived factor-1 (SDF-1) through a c-Src/Akt-dependent signaling pathwayp38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.FoxO1 expression in osteoblasts regulates glucose homeostasis through regulation of osteocalcin in miceMeaning of upper limit of normal range of post-load 1-h plasma glucose level defined by oral glucose tolerance test in Japanese subjects.Current views on type 2 diabetes.Insulin enhances glucose-stimulated insulin secretion in healthy humansSpatholobus suberectus Exhibits Antidiabetic Activity In Vitro and In Vivo through Activation of AKT-AMPK PathwayCyclin D2 is essential for the compensatory beta-cell hyperplastic response to insulin resistance in rodentsGlut4 expression defines an insulin-sensitive hypothalamic neuronal populationRestoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action.Impaired glucose tolerance and predisposition to the fasted state in liver glycogen synthase knock-out miceConsistency of the disposition index in the face of diet induced insulin resistance: potential role of FFA.The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells.Altered insulin receptor signalling and β-cell cycle dynamics in type 2 diabetes mellitusInhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner.Androgen receptor roles in insulin resistance and obesity in males: the linkage of androgen-deprivation therapy to metabolic syndromeIrs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growthGenetic analysis of type-1 insulin-like growth factor receptor signaling through insulin receptor substrate-1 and -2 in pancreatic beta cells.Diabetes in mice with selective impairment of insulin action in Glut4-expressing tissues.Reconstitution of insulin action in muscle, white adipose tissue, and brain of insulin receptor knock-out mice fails to rescue diabetes.Δ40 Isoform of p53 controls β-cell proliferation and glucose homeostasis in mice.Surrogate markers of insulin resistance: A review.Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism.Anorexia and impaired glucose metabolism in mice with hypothalamic ablation of Glut4 neurons.Homeostastic and non-homeostatic functions of melanocortin-3 receptors in the control of energy balance and metabolism.
P2860
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P2860
Lilly lecture 2003: the struggle for mastery in insulin action: from triumvirate to republic.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
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2004年學術文章
@zh-hant
name
Lilly lecture 2003: the strugg ...... from triumvirate to republic.
@en
Lilly lecture 2003: the strugg ...... from triumvirate to republic.
@nl
type
label
Lilly lecture 2003: the strugg ...... from triumvirate to republic.
@en
Lilly lecture 2003: the strugg ...... from triumvirate to republic.
@nl
prefLabel
Lilly lecture 2003: the strugg ...... from triumvirate to republic.
@en
Lilly lecture 2003: the strugg ...... from triumvirate to republic.
@nl
P1433
P1476
Lilly lecture 2003: the strugg ...... from triumvirate to republic.
@en
P304
P356
10.2337/DIABETES.53.7.1633
P407
P577
2004-07-01T00:00:00Z