Adenylyl cyclase type VI corrects cardiac sarcoplasmic reticulum calcium uptake defects in cardiomyopathy.
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Prospects for gene transfer for clinical heart failureRandomized Clinical Trials of Gene Transfer for Heart Failure with Reduced Ejection Fraction.Cardiac-Directed Expression of Adenylyl Cyclase Catalytic Domain Reverses Cardiac Dysfunction Caused by Sustained Beta-Adrenergic Receptor Stimulation.Effects of cardiac overexpression of type 6 adenylyl cyclase affects on the response to chronic pressure overload.Beneficial effects of adenylyl cyclase type 6 (AC6) expression persist using a catalytically inactive AC6 mutant.Adenylyl cyclase 6 improves calcium uptake and left ventricular function in aged heartsActivation of cardiac adenylyl cyclase expression increases function of the failing ischemic heart in mice.Increased ubiquitination and the crosstalk of G protein signaling in cardiac myocytes: involvement of Ric-8B in Gs suppression by Gq signal.Preserved cardiac function despite marked impairment of cAMP generation.Activated expression of cardiac adenylyl cyclase 6 reduces dilation and dysfunction of the pressure-overloaded heart.New signaling pathways associated with increased cardiac adenylyl cyclase 6 expression: implications for possible congestive heart failure therapy.Gene transfer for congestive heart failure: update 2013.cAMP signal transduction in the heart: understanding spatial control for the development of novel therapeutic strategies.Adenylyl cyclase 6 deletion increases mortality during sustained β-adrenergic receptor stimulation.Unanticipated signaling events associated with cardiac adenylyl cyclase gene transfer.Calcium handling in human heart failure--abnormalities and target for therapy.Intracoronary Gene Transfer of Adenylyl Cyclase 6 in Patients With Heart Failure: A Randomized Clinical TrialConcise Review: Mending a Broken Heart: The Evolution of Biological Therapeutics.Adenylyl cyclase type VI increases Akt activity and phospholamban phosphorylation in cardiac myocytes.Galphaq reduces cAMP production by decreasing Galphas protein abundance.
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Adenylyl cyclase type VI corrects cardiac sarcoplasmic reticulum calcium uptake defects in cardiomyopathy.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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name
Adenylyl cyclase type VI corre ...... ake defects in cardiomyopathy.
@en
Adenylyl cyclase type VI corre ...... ake defects in cardiomyopathy.
@nl
type
label
Adenylyl cyclase type VI corre ...... ake defects in cardiomyopathy.
@en
Adenylyl cyclase type VI corre ...... ake defects in cardiomyopathy.
@nl
prefLabel
Adenylyl cyclase type VI corre ...... ake defects in cardiomyopathy.
@en
Adenylyl cyclase type VI corre ...... ake defects in cardiomyopathy.
@nl
P2093
P2860
P1476
Adenylyl cyclase type VI corre ...... ake defects in cardiomyopathy.
@en
P2093
David M Roth
H Kirk Hammond
Mei Hua Gao
P2860
P304
P356
10.1152/AJPHEART.00356.2004
P577
2004-07-08T00:00:00Z