Protein kinase Calpha negatively regulates systolic and diastolic function in pathological hypertrophy
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Protein kinase cascades in the regulation of cardiac hypertrophyPKC translocation and ERK1/2 activation in compensated right ventricular hypertrophy secondary to chronic emphysemaDiacylglycerol Kinase-ε: Properties and Biological RolesThe MLCK-mediated alpha1-adrenergic inotropic effect in atrial myocardium is negatively modulated by PKCepsilon signalingProtein kinase C alpha and epsilon phosphorylation of troponin and myosin binding protein C reduce Ca2+ sensitivity in human myocardiumNuclear localization of protein kinase C-alpha induces thyroid hormone receptor-alpha1 expression in the cardiomyocyteCardiac myosin-binding protein-C phosphorylation and cardiac functionEffects of triiodo-thyronine on angiotensin-induced cardiomyocyte hypertrophy: reversal of increased beta-myosin heavy chain gene expressionMammalian target of rapamycin is a critical regulator of cardiac hypertrophy in spontaneously hypertensive rats.Protein Kinases as Drug Development Targets for Heart Disease TherapyRegulation of cardiac contractility by Rab4-modulated beta2-adrenergic receptor recycling.G alpha(q)-mediated activation of GRK2 by mechanical stretch in cardiac myocytes: the role of protein kinase C.Receptor-independent cardiac protein kinase Calpha activation by calpain-mediated truncation of regulatory domains.Cardiomyocyte-specific loss of diacylglycerol acyltransferase 1 (DGAT1) reproduces the abnormalities in lipids found in severe heart failure.PKCα-specific phosphorylation of the troponin complex in human myocardium: a functional and proteomics analysis.Receptor-independent protein kinase C alpha (PKCalpha) signaling by calpain-generated free catalytic domains induces HDAC5 nuclear export and regulates cardiac transcription.Protein kinase Cα as a heart failure therapeutic targetInhibition of PKCα/β with ruboxistaurin antagonizes heart failure in pigs after myocardial infarction injury.Cardiac GPCRs: GPCR signaling in healthy and failing hearts.AZT-induced mitochondrial toxicity: an epigenetic paradigm for dysregulation of gene expression through mitochondrial oxidative stressPharmacological inhibition of βIIPKC is cardioprotective in late-stage hypertrophy.Cell signalling in the cardiovascular system: an overview.Combined cardiomyocyte PKCδ and PKCε gene deletion uncovers their central role in restraining developmental and reactive heart growthObesity-related alterations in cardiac lipid profile and nondipping blood pressure pattern during transition to diastolic dysfunction in male db/db miceProtein kinase C depresses cardiac myocyte power output and attenuates myofilament responses induced by protein kinase AMLP and CARP are linked to chronic PKCα signalling in dilated cardiomyopathy.With great power comes great responsibility: using mouse genetics to study cardiac hypertrophy and failure.Inducible and myocyte-specific inhibition of PKCalpha enhances cardiac contractility and protects against infarction-induced heart failure.Pharmacological- and gene therapy-based inhibition of protein kinase Calpha/beta enhances cardiac contractility and attenuates heart failure.Myocardial Hsp70 phosphorylation and PKC-mediated cardioprotection following exercise.Disruption of ROCK1 gene attenuates cardiac dilation and improves contractile function in pathological cardiac hypertrophy.Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approachThe role of mid-chain hydroxyeicosatetraenoic acids in the pathogenesis of hypertension and cardiac hypertrophy.Breviscapine ameliorates hypertrophy of cardiomyocytes induced by high glucose in diabetic rats via the PKC signaling pathway.Protein kinase C and cardiac dysfunction: a review.Protein kinase C (PKC) activity regulates functional effects of Kvβ1.3 subunit on KV1.5 channels: identification of a cardiac Kv1.5 channelosomeDistinct pathways regulate proapoptotic Nix and BNip3 in cardiac stress.Characterizing genetic variation of adrenergic signalling pathways in Takotsubo (stress) cardiomyopathy exomes.PKC inhibition results in a Kv 1.5 + Kv β1.3 pharmacology closer to Kv 1.5 channels.Adenylyl cyclase type VI corrects cardiac sarcoplasmic reticulum calcium uptake defects in cardiomyopathy.
P2860
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P2860
Protein kinase Calpha negatively regulates systolic and diastolic function in pathological hypertrophy
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Protein kinase Calpha negative ...... on in pathological hypertrophy
@ast
Protein kinase Calpha negative ...... on in pathological hypertrophy
@en
Protein kinase Calpha negative ...... on in pathological hypertrophy
@en-gb
Protein kinase Calpha negative ...... on in pathological hypertrophy
@nl
type
label
Protein kinase Calpha negative ...... on in pathological hypertrophy
@ast
Protein kinase Calpha negative ...... on in pathological hypertrophy
@en
Protein kinase Calpha negative ...... on in pathological hypertrophy
@en-gb
Protein kinase Calpha negative ...... on in pathological hypertrophy
@nl
prefLabel
Protein kinase Calpha negative ...... on in pathological hypertrophy
@ast
Protein kinase Calpha negative ...... on in pathological hypertrophy
@en
Protein kinase Calpha negative ...... on in pathological hypertrophy
@en-gb
Protein kinase Calpha negative ...... on in pathological hypertrophy
@nl
P921
P3181
P1433
P1476
Protein kinase Calpha negative ...... on in pathological hypertrophy
@en
P2093
H. S. Hahn
P2880
P304
P3181
P356
10.1161/01.RES.0000105087.79373.17
P407
P577
2003-11-28T00:00:00Z