Identification of small molecule synthetic inhibitors of DNA polymerase beta by NMR chemical shift mapping. - Wikidata - wikimedia - TriplyDB

Identification of small molecule synthetic inhibitors of DNA polymerase beta by NMR chemical shift mapping.

Identification of small molecule synthetic inhibitors of DNA polymerase beta by NMR chemical shift mapping.

http://www.wikidata.org/entity/Q44982151

about

Solution structure of GOPC PDZ domain and its interaction with the C-terminal motif of neuroligin Differential ubiquitin binding of the UBA domains from human c-Cbl and Cbl-b: NMR structural and biochemical insights Structural Basis for Ubiquitin Recognition by a Novel Domain from Human Phospholipase A2-activating Protein Solution structure of the N-terminal domain of DC-UbP/UBTD2 and its interaction with ubiquitin Structural insights on the pamoic acid and the 8 kDa domain of DNA polymerase beta complex: towards the design of higher-affinity inhibitors.Biomolecular NMR data analysis Structural transformation of the tandem ubiquitin-interacting motifs in ataxin-3 and their cooperative interactions with ubiquitin chains.DNA polymerases as potential therapeutic targets for cancers deficient in the DNA mismatch repair proteins MSH2 or MLH1 Hyperactivation of PARP triggers nonhomologous end-joining in repair-deficient mouse fibroblasts.Interaction between DNA Polymerase β and BRCA1 Two novel determinants of etoposide resistance in small cell lung cancer.Hypersensitivity phenotypes associated with genetic and synthetic inhibitor-induced base excision repair deficiency Base excision repair and design of small molecule inhibitors of human DNA polymerase β.Base excision repair: contribution to tumorigenesis and target in anticancer treatment paradigms Molecular mechanism of adenomatous polyposis coli-induced blockade of base excision repair pathway in colorectal carcinogenesis.XRCC1 and DNA polymerase beta in cellular protection against cytotoxic DNA single-strand breaks.Balancing repair and tolerance of DNA damage caused by alkylating agents Evidence for base excision repair processing of DNA interstrand crosslinks.DNA repair proteins as molecular targets for cancer therapeutics.A real-time fluorescence method for enzymatic characterization of specialized human DNA polymerases.Amino acid Asp181 of 5'-flap endonuclease 1 is a useful target for chemotherapeutic development.A novel inhibitor of DNA polymerase beta enhances the ability of temozolomide to impair the growth of colon cancer cells.Targeting DNA polymerase ß for therapeutic intervention.Non-clinical toxicological considerations for pharmaceutical salt selection.Amplification of unscheduled DNA synthesis signal enables fluorescence-based single cell quantification of transcription-coupled nucleotide excision repair.Honokiol Inhibits DNA Polymerases β and λ and Increases Bleomycin Sensitivity of Human Cancer Cells.1,3-Bis(2-chloroethyl)-1-nitrosourea enhances the inhibitory effect of resveratrol on 5-fluorouracil sensitive/resistant colon cancer cells.The primary DNA-binding subsite of the rat pol β. Energetics of interactions of the 8-kDa domain of the enzyme with the ssDNA

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P2860

Identification of small molecule synthetic inhibitors of DNA polymerase beta by NMR chemical shift mapping.

http://www.wikidata.org/entity/Q44982151

description

2004 nî lūn-bûn

@nan

2004年の論文

@ja

2004年学术文章

@wuu

2004年学术文章

@zh

2004年学术文章

@zh-cn

2004年学术文章

@zh-hans

2004年学术文章

@zh-my

2004年学术文章

@zh-sg

2004年學術文章

@yue

2004年學術文章

@zh-hant

name

Identification of small molecu ...... by NMR chemical shift mapping.

@en

Identification of small molecu ...... by NMR chemical shift mapping.

@nl

type

label

Identification of small molecu ...... by NMR chemical shift mapping.

@en

Identification of small molecu ...... by NMR chemical shift mapping.

@nl

prefLabel

Identification of small molecu ...... by NMR chemical shift mapping.

@en

Identification of small molecu ...... by NMR chemical shift mapping.

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

Identification of small molecu ...... by NMR chemical shift mapping

@en

P2093

Di-An Sun

http://www.w3.org/2001/XMLSchema#string

Gregory P Mullen

http://www.w3.org/2001/XMLSchema#string

Hong-Yu Hu

http://www.w3.org/2001/XMLSchema#string

Jana M Naron

http://www.w3.org/2001/XMLSchema#string

Julie K Horton

http://www.w3.org/2001/XMLSchema#string

Michael R Gryk

http://www.w3.org/2001/XMLSchema#string

Rajendra Prasad

http://www.w3.org/2001/XMLSchema#string

Sidney M Hecht

http://www.w3.org/2001/XMLSchema#string

P2860

Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs

Backbone dynamics and refined solution structure of the N-terminal domain of DNA polymerase beta. Correlation with DNA binding and dRP lyase activity

Three-dimensional solution structure of the N-terminal domain of DNA polymerase beta and mapping of the ssDNA interaction interface

Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism

bis-5-Alkylresorcinols from Panopsis rubescens that inhibit DNA polymerase beta.

DNA polymerase beta inhibitors from Sandoricum koetjape.

DNA polymerase beta inhibitors from Tetracera boiviniana.

Pentacyclic triterpenoids from Freziera sp. that inhibit DNA polymerase beta.

A new 7,8-euphadien-type triterpenoid from Brackenridgea nitida and Bleasdalea bleasdalei that inhibits DNA polymerase beta.

Interactions of the products, 8-oxo-dGMP, dGMP, and pyrophosphate with the MutT nucleoside triphosphate pyrophosphohydrolase.

P304

39736-39744

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scholarly article

P356

10.1074/JBC.M402842200

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P433

38

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P478

279

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P50

Samuel H. Wilson

P577

2004-07-15T00:00:00Z

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P698

15258144

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