Cytokine production, glutamate release and cell death in rat cultured astrocytes treated with unconjugated bilirubin and LPS.
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Rat cerebellar slice cultures exposed to bilirubin evidence reactive gliosis, excitotoxicity and impaired myelinogenesis that is prevented by AMPA and TNF-α inhibitorsMicroglia change from a reactive to an age-like phenotype with the time in cultureN-methyl-aspartate receptor and neuronal nitric oxide synthase activation mediate bilirubin-induced neurotoxicityExposure to lipopolysaccharide and/or unconjugated bilirubin impair the integrity and function of brain microvascular endothelial cellsEx vivo (1)H nuclear magnetic resonance spectroscopy reveals systematic alterations in cerebral metabolites as the key pathogenetic mechanism of bilirubin encephalopathy.The evolving landscape of neurotoxicity by unconjugated bilirubin: role of glial cells and inflammation.Biological risks for neurological abnormalities associated with hyperbilirubinemia.Inflammatory signature of cerebellar neurodegeneration during neonatal hyperbilirubinemia in Ugt1 -/- mouse model.Risk factors of organ failure in patients with bacteremic cholangitis.Brain Barrier Breakdown as a Cause and Consequence of Neuroinflammation in Sepsis.Protective effect of melatonin on methamphetamine-induced apoptosis in glioma cell line.Nuclear factor κB down-regulates human UDP-glucuronosyltransferase 1A1: a novel mechanism involved in inflammation-associated hyperbilirubinaemia.Unconjugated bilirubin modulates the intestinal epithelial barrier function in a human-derived in vitro model.Effects of bilirubin on neutrophil responses in newborn infants.Cadmium and arsenic override NF-κB developmental regulation of the intestinal UGT1A1 gene and control of hyperbilirubinemia.A Hypothesis for Using Pathway Genetic Load Analysis for Understanding Complex Outcomes in Bilirubin EncephalopathyBilirubin as a determinant for altered neurogenesis, neuritogenesis, and synaptogenesis.Trazodone regulates neurotrophic/growth factors, mitogen-activated protein kinases and lactate release in human primary astrocytes.Time-dependent dual effects of high levels of unconjugated bilirubin on the human blood-brain barrier lining.Tumor necrosis factor-alpha modulates glutamate transport in the CNS and is a critical determinant of outcome from viral encephalomyelitisA novel brain injury mechanism after intracerebral hemorrhage: the interaction between heme products and the immune system.Cerebellar axon/myelin loss, angiogenic sprouting, and neuronal increase of vascular endothelial growth factor in a preterm infant with kernicterus.Cross-talk between neurons and astrocytes in response to bilirubin: adverse secondary impacts.Dynamics of neuron-glia interplay upon exposure to unconjugated bilirubin.Tet1-mediated DNA demethylation involves in neuron damage induced by bilirubin in vitro.Kernicterus in a neonatal foal.Neuroprotective Effect of Erythropoietin on Phenylhydrazine-Induced Hemolytic Hyperbilirubinemia in Neonatal Rats.ER stress, mitochondrial dysfunction and calpain/JNK activation are involved in oligodendrocyte precursor cell death by unconjugated bilirubin.Inflammatory signalling pathways involved in astroglial activation by unconjugated bilirubin.Neuro-inflammatory effects of photodegradative products of bilirubin.
P2860
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P2860
Cytokine production, glutamate release and cell death in rat cultured astrocytes treated with unconjugated bilirubin and LPS.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Cytokine production, glutamate ...... nconjugated bilirubin and LPS.
@en
Cytokine production, glutamate ...... nconjugated bilirubin and LPS.
@nl
type
label
Cytokine production, glutamate ...... nconjugated bilirubin and LPS.
@en
Cytokine production, glutamate ...... nconjugated bilirubin and LPS.
@nl
prefLabel
Cytokine production, glutamate ...... nconjugated bilirubin and LPS.
@en
Cytokine production, glutamate ...... nconjugated bilirubin and LPS.
@nl
P50
P1476
Cytokine production, glutamate ...... nconjugated bilirubin and LPS.
@en
P2093
Rui F M Silva
P356
10.1016/J.JNEUROIM.2004.04.007
P577
2004-08-01T00:00:00Z