Low-density lipoprotein receptor gene therapy using helper-dependent adenovirus produces long-term protection against atherosclerosis in a mouse model of familial hypercholesterolemia.
about
Identification and functional characterization in vivo of a novel splice variant of LDLR in rhesus macaquesGene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosisLong-term physiologically regulated expression of the low-density lipoprotein receptor in vivo using genomic DNA mini-gene constructsGene therapy for monogenic liver diseases: clinical successes, current challenges and future prospects.Inhibition and regression of atherosclerotic lesions.LDLR-Gene therapy for familial hypercholesterolaemia: problems, progress, and perspectivesGene therapy for rhesus monkeys heterozygous for LDL receptor deficiency by balloon catheter hepatic delivery of helper-dependent adenoviral vector.Helper-dependent adenoviral vectors for liver-directed gene therapy.Aggressive very low-density lipoprotein (VLDL) and LDL lowering by gene transfer of the VLDL receptor combined with a low-fat diet regimen induces regression and reduces macrophage content in advanced atherosclerotic lesions in LDL receptor-deficienCloning and expression profiling of the VLDLR gene associated with egg performance in duck (Anas platyrhynchos).Sustained phenotypic correction in a mouse model of hypoalphalipoproteinemia with a helper-dependent adenovirus vector.Effects of High Fat Feeding and Diabetes on Regression of Atherosclerosis Induced by Low-Density Lipoprotein Receptor Gene Therapy in LDL Receptor-Deficient MiceGene therapy for dyslipidemia: a review of gene replacement and gene inhibition strategiesGene therapy for lipoprotein disorders.Helper-dependent adenoviral vectors in experimental gene therapy.Gene Therapy Targeting LDL Cholesterol but not HDL Cholesterol Induces Regression of Advanced Atherosclerosis in a Mouse Model of Familial HypercholesterolemiaProgress and prospects: gene therapy for genetic diseases with helper-dependent adenoviral vectors.Episomal Nonviral Gene Therapy Vectors Slow Progression of Atherosclerosis in a Model of Familial Hypercholesterolemia.AAV-mediated gene therapy for liver diseases: the prime candidate for clinical application?RNAi-mediated knockdown of HMG CoA reductase enhances gene expression from physiologically regulated low-density lipoprotein receptor therapeutic vectors in vivo.A rapid protocol for construction and production of high-capacity adenoviral vectors.Neo-islet formation in liver of diabetic mice by helper-dependent adenoviral vector-mediated gene transfer.Construction and application of a novel hepatocyte-directed vector to simultaneous knockdown and overexpression of multiple genes.Rescue administration of a helper-dependent adenovirus vector with long-term efficacy in dogs with glycogen storage disease type Ia.Insights From Pre-Clinical and Clinical Studies on the Role of Innate Inflammation in Atherosclerosis Regression.
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P2860
Low-density lipoprotein receptor gene therapy using helper-dependent adenovirus produces long-term protection against atherosclerosis in a mouse model of familial hypercholesterolemia.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Low-density lipoprotein recept ...... familial hypercholesterolemia.
@en
Low-density lipoprotein recept ...... familial hypercholesterolemia.
@nl
type
label
Low-density lipoprotein recept ...... familial hypercholesterolemia.
@en
Low-density lipoprotein recept ...... familial hypercholesterolemia.
@nl
prefLabel
Low-density lipoprotein recept ...... familial hypercholesterolemia.
@en
Low-density lipoprotein recept ...... familial hypercholesterolemia.
@nl
P2093
P2860
P921
P356
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P1476
Low-density lipoprotein recept ...... familial hypercholesterolemia.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.GT.3302310
P577
2004-10-01T00:00:00Z
P5875
P6179
1033960591