P2X7 receptor polymorphism impairs extracellular adenosine 5'-triphosphate-induced interleukin-18 release from human monocytes.
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Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal womenThe P2X7 receptor is a candidate product of murine and human lupus susceptibility loci: a hypothesis and comparison of murine allelic productsPurinergic receptors P2RX4 and P2RX7 in familial multiple sclerosis.High expression of the ectonucleotidase CD39 on T cells from the inflamed site identifies two distinct populations, one regulatory and one memory T cell populationP2X7 receptor-mediated killing of an intracellular parasite, Toxoplasma gondii, by human and murine macrophages.Non-synonymous single nucleotide polymorphisms in the P2X receptor genes: association with diseases, impact on receptor functions and potential use as diagnosis biomarkersThe P2X(7) loss-of-function Glu496Ala polymorphism affects ex vivo cytokine release and protects against the cytotoxic effects of high ATP-levels.The role of nucleotides and purinergic signaling in apoptotic cell clearance - implications for chronic inflammatory diseases.Probenecid blocks human P2X7 receptor-induced dye uptake via a pannexin-1 independent mechanism.Bone marrow-derived mesenchymal stromal cells harness purinergenic signaling to tolerize human Th1 cells in vivo.Lack of a Functioning P2X7 Receptor Leads to Increased Susceptibility to Toxoplasmic Ileitis.CpG-induced IFNgamma expands TLR4-specific IL-18 responses in vivo.Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fracturesP2X receptor characterization and IL-1/IL-1Ra release from human endothelial cellsP2 purinergic receptor modulation of cytokine production.Expression, signaling, and function of P2X7 receptors in bone.The P2X(7) receptor and intracellular pathogens: a continuing struggle.Epistasis with HLA DR3 implicates the P2X7 receptor in the pathogenesis of primary Sjögren's syndrome.Inflammasomes in carcinogenesis and anticancer immune responses.Calcium Channels and Associated Receptors in Malignant Brain Tumor Therapy.Contribution of the P2X7 1513A/C loss-of-function polymorphism to extrapulmonary tuberculosis susceptibility in Tunisian populations.The ATP Receptors P2X7 and P2X4 Modulate High Glucose and Palmitate-Induced Inflammatory Responses in Endothelial Cells.A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis.C-terminal calmodulin-binding motif differentially controls human and rat P2X7 receptor current facilitation.Overexpression of ATP-activated P2X7 receptors in the intestinal mucosa is implicated in the pathogenesis of Crohn's disease.Residues 155 and 348 contribute to the determination of P2X7 receptor function via distinct mechanisms revealed by single-nucleotide polymorphisms.P2X7 and NRAMP1/SLC11 A1 gene polymorphisms in Mexican mestizo patients with pulmonary tuberculosis.Interleukin-18 secretion and Th1-like cytokine responses in human peripheral blood mononuclear cells under the influence of the toll-like receptor-5 ligand flagellin.A 5' intronic splice site polymorphism leads to a null allele of the P2X7 gene in 1-2% of the Caucasian population.
P2860
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P2860
P2X7 receptor polymorphism impairs extracellular adenosine 5'-triphosphate-induced interleukin-18 release from human monocytes.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
P2X7 receptor polymorphism imp ...... release from human monocytes.
@en
P2X7 receptor polymorphism imp ...... release from human monocytes.
@nl
type
label
P2X7 receptor polymorphism imp ...... release from human monocytes.
@en
P2X7 receptor polymorphism imp ...... release from human monocytes.
@nl
prefLabel
P2X7 receptor polymorphism imp ...... release from human monocytes.
@en
P2X7 receptor polymorphism imp ...... release from human monocytes.
@nl
P356
P1433
P1476
P2X7 receptor polymorphism imp ...... release from human monocytes.
@en
P2093
P2888
P304
P356
10.1038/SJ.GENE.6364127
P577
2004-11-01T00:00:00Z
P5875
P6179
1021781427