A 5' intronic splice site polymorphism leads to a null allele of the P2X7 gene in 1-2% of the Caucasian population.
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Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal womenExpression and function of P2 receptors in hematopoietic stem and progenitor cellsExpression of P2 receptors in human B cells and Epstein-Barr virus-transformed lymphoblastoid cell lines.The hyposensitive N187D P2X7 mutant promotes malignant progression in nude mice.Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fracturesP2X receptor characterization and IL-1/IL-1Ra release from human endothelial cellsThe specificity protein factor Sp1 mediates transcriptional regulation of P2X7 receptors in the nervous system.P2 purinergic receptor modulation of cytokine production.Cell signaling via the P2X(7) nucleotide receptor: linkage to ROS production, gene transcription, and receptor traffickingThe P2X(7) receptor and intracellular pathogens: a continuing struggle.Genetics of the P2X7 receptor and human disease.P2X(7) receptor at the heart of disease.Population- and individual-specific regulatory variation in Sardinia.Targeting P2X₇ receptor inhibits the metastasis of murine P388D1 lymphoid neoplasm cells to lymph nodes.Features of 5'-splice-site efficiency derived from disease-causing mutations and comparative genomics.Hyperthermia and associated changes in membrane fluidity potentiate P2X7 activation to promote tumor cell death.Characterisation of the R276A gain-of-function mutation in the ectodomain of murine P2X7The P2X7 receptor gene polymorphism 1513 A-->C has no effect on clinical prognostic markers and survival in multiple myeloma.The P2X7 Receptor in Inflammatory Diseases: Angel or Demon?The P2X7 Receptor.
P2860
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P2860
A 5' intronic splice site polymorphism leads to a null allele of the P2X7 gene in 1-2% of the Caucasian population.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
A 5' intronic splice site poly ...... % of the Caucasian population.
@en
A 5' intronic splice site poly ...... % of the Caucasian population.
@nl
type
label
A 5' intronic splice site poly ...... % of the Caucasian population.
@en
A 5' intronic splice site poly ...... % of the Caucasian population.
@nl
prefLabel
A 5' intronic splice site poly ...... % of the Caucasian population.
@en
A 5' intronic splice site poly ...... % of the Caucasian population.
@nl
P2093
P2860
P1433
P1476
A 5' intronic splice site poly ...... % of the Caucasian population.
@en
P2093
James S Wiley
Kristen K Skarratt
Lan-Phuong Dao-Ung
Stephen J Fuller
P2860
P304
P356
10.1016/J.FEBSLET.2005.03.091
P407
P577
2005-04-14T00:00:00Z