Pore formation by equinatoxin, a eukaryotic pore-forming toxin, requires a flexible N-terminal region and a stable beta-sandwich.
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The Rise and Fall of an Evolutionary Innovation: Contrasting Strategies of Venom Evolution in Ancient and Young AnimalsA common toxin fold mediates microbial attack and plant defenseMembrane damage by an α-helical pore-forming protein, Equinatoxin II, proceeds through a succession of ordered stepsCrystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunitStructural basis for self-assembly of a cytolytic pore lined by protein and lipidSolution NMR analysis of the interaction between the actinoporin sticholysin I and DHPC micelles--correlation with backbone dynamics.Imaging the lipid-phase-dependent pore formation of equinatoxin II in droplet interface bilayers.Characterization of the Lipid-Binding Site of Equinatoxin II by NMR and Molecular Dynamics SimulationInfrared spectroscopy study on the conformational changes leading to pore formation of the toxin sticholysin II.Oligomerization and pore formation by equinatoxin II inhibit endocytosis and lead to plasma membrane reorganization.Hct-a is a new actinoporin family from the heteractis crispa sea anemone.Equinatoxin II permeabilizing activity depends on the presence of sphingomyelin and lipid phase coexistenceA pore-forming toxin requires a specific residue for its activity in membranes with particular physicochemical properties.Evolution of an ancient venom: recognition of a novel family of cnidarian toxins and the common evolutionary origin of sodium and potassium neurotoxins in sea anemone.Mutagenesis and functional analysis of the pore-forming toxin HALT-1 from Hydra magnipapillata.Differential effect of solution conditions on the conformation of the actinoporins Sticholysin II and Equinatoxin II.Toxicity of an α-pore-forming toxin depends on the assembly mechanism on the target membrane as revealed by single molecule imaging.Selective permeabilization of the host cell membrane of Plasmodium falciparum-infected red blood cells with streptolysin O and equinatoxin IIA toxin-based probe reveals cytoplasmic exposure of Golgi sphingomyelinThe effect of cholesterol on the long-range network of interactions established among sea anemone Sticholysin II residues at the water-membrane interfaceMembrane binding of zebrafish actinoporin-like protein: AF domains, a novel superfamily of cell membrane binding domains.Interconversion between bound and free conformations of LexA orchestrates the bacterial SOS response.Photobleaching reveals heterogeneous stoichiometry for equinatoxin II oligomers.Biophysical and biochemical strategies to understand membrane binding and pore formation by sticholysins, pore-forming proteins from a sea anemone.Lysenin-His, a sphingomyelin-recognizing toxin, requires tryptophan 20 for cation-selective channel assembly but not for membrane binding.Self-homodimerization of an actinoporin by disulfide bridging reveals implications for their structure and pore formation.Multigene Family of Pore-Forming Toxins from Sea Anemone Heteractis crispa.The equinatoxin N-terminus is transferred across planar lipid membranes and helps to stabilize the transmembrane pore
P2860
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P2860
Pore formation by equinatoxin, a eukaryotic pore-forming toxin, requires a flexible N-terminal region and a stable beta-sandwich.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
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2004年學術文章
@zh-hant
name
Pore formation by equinatoxin, ...... on and a stable beta-sandwich.
@en
Pore formation by equinatoxin, ...... on and a stable beta-sandwich.
@nl
type
label
Pore formation by equinatoxin, ...... on and a stable beta-sandwich.
@en
Pore formation by equinatoxin, ...... on and a stable beta-sandwich.
@nl
prefLabel
Pore formation by equinatoxin, ...... on and a stable beta-sandwich.
@en
Pore formation by equinatoxin, ...... on and a stable beta-sandwich.
@nl
P2093
P2860
P50
P356
P1476
Pore formation by equinatoxin, ...... on and a stable beta-sandwich.
@en
P2093
Dusan Turk
Gregor Guncar
Ion Gutiérrez-Aguirre
Juan M González-Mañas
Katarina Kristan
Vesna Hojnik
Zdravko Podlesek
P2860
P304
46509-46517
P356
10.1074/JBC.M406193200
P407
P577
2004-08-20T00:00:00Z