Searching for silver bullets: an alternative strategy for crystallizing macromolecules.
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X-ray crystallography: Assessment and validation of protein-small molecule complexes for drug discovery.Protein crystallization screens developed at the MRC Laboratory of Molecular BiologyThe use of polyoxometalates in protein crystallography – An attempt to widen a well-known bottleneckA historical perspective on protein crystallization from 1840 to the present dayControlled in meso phase crystallization--a method for the structural investigation of membrane proteinsStructural basis of gate-DNA breakage and resealing by type II topoisomerasesStructural genomics and drug discovery for infectious diseasesA new crystal form of bovine pancreatic RNase A in complex with 2′-deoxyguanosine-5′-monophosphateDetermination of protein structures--a series of fortunate events.High-resolution structure of proteinase K cocrystallized with digalacturonic acidStructure of pig heart citrate synthase at 1.78 Å resolutionOperator-assisted harvesting of protein crystals using a universal micromanipulation robotFunction-biased choice of additives for optimization of protein crystallization - the case of the putative thioesterase PA5185 from Pseudomonas aeruginosa PAO1Structure of the GTPase and GDI domains of FeoB, the ferrous iron transporter of Legionella pneumophilaStructural Homology between the C-Terminal Domain of the PapC Usher and Its PlugStructure of bovine pancreatic ribonuclease complexed with uridine 5′-monophosphate at 1.60 Å resolutionAn improved strategy for the crystallization ofLeishmania mexicanapyruvate kinaseStructure of Estradiol Metal Chelate and Estrogen Receptor Complex: The Basis for Designing a New Class of Selective Estrogen Receptor ModulatorsThe use of trimethylamineN-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallographyStructure of an 'open' clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transportCocrystal Structures of Glycyl-tRNA Synthetase in Complex with tRNA Suggest Multiple Conformational States in GlycylationProtein stability: a crystallographer's perspectiveBenefits of structural genomics for drug discovery researchExploring the active site of the Streptococcus pneumoniae topoisomerase IV-DNA cleavage complex with novel 7,8-bridged fluoroquinolonesThe "Sticky Patch" Model of Crystallization and Modification of Proteins for Enhanced Crystallizability.Hen egg-white lysozyme crystallisation: protein stacking and structure stability enhanced by a Tellurium(VI)-centred polyoxotungstateThe MORPHEUS II protein crystallization screenCrystallization screening: the influence of history on current practice.To automate or not to automate: this is the question.The current approach to initial crystallization screening of proteins is under-sampled.Protein crystallization in drug design: towards a rational approach.Squeezing the most from every crystal: the fine details of data collection.FASTDXL: a generalized screen to trap disulfide-stabilized complexes for use in structural studiesTen Good Reasons for the Use of the Tellurium-Centered Anderson-Evans Polyoxotungstate in Protein CrystallographyCrystallization and preliminary X-ray analysis of the chemokine-binding protein from orf virus (Poxviridae)Optimization of crystallization conditions for biological macromolecules.Crystal cookery - using high-throughput technologies and the grocery store as a teaching tool.Enhancement of crystallization with nucleotide ligands identified by dye-ligand affinity chromatography.Large Conformational Changes of Insertion 3 in Human Glycyl-tRNA Synthetase (hGlyRS) during Catalysis.Lessons from high-throughput protein crystallization screening: 10 years of practical experience.
P2860
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P2860
Searching for silver bullets: an alternative strategy for crystallizing macromolecules.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Searching for silver bullets: an alternative strategy for crystallizing macromolecules.
@en
Searching for silver bullets: an alternative strategy for crystallizing macromolecules.
@nl
type
label
Searching for silver bullets: an alternative strategy for crystallizing macromolecules.
@en
Searching for silver bullets: an alternative strategy for crystallizing macromolecules.
@nl
prefLabel
Searching for silver bullets: an alternative strategy for crystallizing macromolecules.
@en
Searching for silver bullets: an alternative strategy for crystallizing macromolecules.
@nl
P1476
Searching for silver bullets: an alternative strategy for crystallizing macromolecules.
@en
P2093
Alexander McPherson
Bob Cudney
P304
P356
10.1016/J.JSB.2006.09.006
P577
2006-10-11T00:00:00Z