Structure-activity relationships in steroidal anaesthetics.

Structure-activity relationships in steroidal anaesthetics.

Item
http://www.wikidata.org/entity/Q45093844
In a mouse model relevant for post-traumatic stress disorder, selective brain steroidogenic stimulants (SBSS) improve behavioral deficits by normalizing allopregnanolone biosynthesis.Cyclodextrins sequester neuroactive steroids and differentiate mechanisms that rate limit steroid actionsNeurosteroid analogues. 17. Inverted binding orientations of androsterone enantiomers at the steroid potentiation site on γ-aminobutyric acid type A receptorsMechanisms of neurosteroid interactions with GABA(A) receptors.5α-reduced progestogens ameliorate mood-related behavioral pathology, neurotoxicity, and microgliosis associated with exposure to HIV-1 Tat.The role of neurosteroids in the pathophysiology and treatment of catamenial epilepsy.Catamenial epilepsy: hormonal aspects.The sticky issue of neurosteroids and GABA(A) receptors.Neurosteroid Analogues. 13. Synthetic methods for the preparation of 2beta-hydroxygonane derivatives as structural mimics of ent-3alpha-hydroxysteroid modulators of GABA(A) receptorsIn vivo studies identify 5 alpha-pregnan-3 alpha-ol-20-one as an active anesthetic agent.Neurosteroid analogues. 15. A comparative study of the anesthetic and GABAergic actions of alphaxalone, Δ16-alphaxalone and their corresponding 17-carbonitrile analogues.Abnormal Beckmann fragmentation/ring closing metathesis route for preparation of 18-nor-Delta-androgens and their 18-nor-13,17-epoxide derivativesGABAA and glycine receptor-mediated transmission in rat lamina II neurones: relevance to the analgesic actions of neuroactive steroids.The inhibitory effects of allopregnanolone and pregnanolone on the population spike, evoked in the rat hippocampal CA1 stratum pyramidale in vitro, can be blocked selectively by epiallopregnanolone.Effect of ganaxolone on flurothyl seizures in developing rats.
P2860

Structure-activity relationships in steroidal anaesthetics.

Item
http://www.wikidata.org/entity/Q45093844
description
1975 nî lūn-bûn
@nan
1975年の論文
@ja
1975年学术文章
@wuu
1975年学术文章
@zh
1975年学术文章
@zh-cn
1975年学术文章
@zh-hans
1975年学术文章
@zh-my
1975年学术文章
@zh-sg
1975年學術文章
@yue
1975年學術文章
@zh-hant
name
Structure-activity relationships in steroidal anaesthetics.
@en
Structure-activity relationships in steroidal anaesthetics.
@nl
type
label
Structure-activity relationships in steroidal anaesthetics.
@en
Structure-activity relationships in steroidal anaesthetics.
@nl
prefLabel
Structure-activity relationships in steroidal anaesthetics.
@en
Structure-activity relationships in steroidal anaesthetics.
@nl
P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
Structure-activity relationships in steroidal anaesthetics.
@en
P2093
P304
P31
P356
10.1016/0022-4731(75)90041-2
P433
P478
P577
P698